{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T13:28:28Z","timestamp":1775654908538,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,4,19]],"date-time":"2017-04-19T00:00:00Z","timestamp":1492560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Birth"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>After China's One\u2010child Policy was replaced with the Two\u2010child Policy in 2013, the rate of second pregnancies with a longer inter\u2010pregnancy interval (<jats:styled-content style=\"fixed-case\">IPI<\/jats:styled-content>) has suddenly increased in that country; however, the effect of long <jats:styled-content style=\"fixed-case\">IPI<\/jats:styled-content>s (\u226549\u00a0months) on perinatal outcomes remains unreported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective cohort study in China from July 2015 through June 2016. We used univariate and multivariate logistic regression models to test the associations among <jats:styled-content style=\"fixed-case\">IPI<\/jats:styled-content>, maternal age, and perinatal outcome (preterm delivery, term low birthweight, and small\u2010for\u2010gestational age). We included baseline factors and variables with biological plausibility as confounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our analytic sample included 3309\u00a0second pregnancies. The mean <jats:styled-content style=\"fixed-case\">IPI<\/jats:styled-content> was 75.36\u00a0months. Compared with second pregnancies with a short <jats:styled-content style=\"fixed-case\">IPI<\/jats:styled-content> of 7\u201024\u00a0months, those with long <jats:styled-content style=\"fixed-case\">IPI<\/jats:styled-content>s had higher adjusted odds ratios (ORs) of preterm delivery (1.70\u20102.00 [95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.20\u20103.33]) and term low birthweight (2.16\u20102.68 [1.10\u20106.17]), but not small\u2010for\u2010gestational age. The mean maternal age at current delivery was 32.0\u00a0years. Compared with the reference group (25\u201029\u00a0years), second pregnancies for the oldest maternal age group (\u226535\u00a0years) showed no statistically significant increased <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>s for adverse perinatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Long <jats:styled-content style=\"fixed-case\">IPI<\/jats:styled-content> is a significant contributor to preterm delivery and term low birthweight. Health care providers need to pay close attention to preterm delivery prevention and fetal growth during prenatal care for second pregnancies where the mothers have long <jats:styled-content style=\"fixed-case\">IPI<\/jats:styled-content>s.<\/jats:p><\/jats:sec>","DOI":"10.1111\/birt.12289","type":"journal-article","created":{"date-parts":[[2017,4,19]],"date-time":"2017-04-19T06:03:04Z","timestamp":1492581784000},"page":"230-237","source":"Crossref","is-referenced-by-count":30,"title":["A first look at the effects of long inter\u2010pregnancy interval and advanced maternal age on perinatal outcomes: A retrospective cohort study"],"prefix":"10.1111","volume":"44","author":[{"given":"Chunxiang","family":"Qin","sequence":"first","affiliation":[{"name":"Obstetrical Department The Third Xiangya Hospital Central South University  Changsha China"},{"name":"Xiangya School of Nursing Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunmei","family":"Mi","sequence":"additional","affiliation":[{"name":"Obstetrical Department The Third Xiangya Hospital Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aibin","family":"Xia","sequence":"additional","affiliation":[{"name":"Obstetrical Department The Third Xiangya Hospital Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei\u2010Ti","family":"Chen","sequence":"additional","affiliation":[{"name":"Yale School of Nursing, Yale University  New Haven CT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunxia","family":"Chen","sequence":"additional","affiliation":[{"name":"Obstetrical Department The Third Xiangya Hospital Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Li","sequence":"additional","affiliation":[{"name":"Neonatology Department The Third Xiangya Hospital Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao","family":"Li","sequence":"additional","affiliation":[{"name":"Xiangya School of Nursing Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenhui","family":"Bai","sequence":"additional","affiliation":[{"name":"Xiangya School of Nursing Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9940-5072","authenticated-orcid":false,"given":"Siyuan","family":"Tang","sequence":"additional","affiliation":[{"name":"Xiangya School of Nursing Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.12.008"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(15)30197-3"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000171118.79529.a3"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.06.042"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12783"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2009.06.006"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-016-0929-5"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13625"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2008.00808.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199902253400801"},{"key":"e_1_2_6_12_1","unstructured":"Wen Xin.The history of population planning in China. 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