{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T20:56:39Z","timestamp":1757451399248,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>It has been suggested that women admitted for delivery should have universal PCR testing for SARS\u2010CoV\u20102. Yet, the considerable difference in the incidence of COVID\u201019 between different geographic regions may affect screening strategies. Therefore, we aimed to compare questionnaire\u2010based testing versus universal PCR testing for SARS\u2010CoV\u20102 in women admitted for delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective cohort study of women admitted for delivery at a single center during a four\u2010week period (April 22\u2010May 25, 2020). All women completed a questionnaire about COVID\u201019 signs, symptoms, or risk factors, and a nasopharyngeal swab for PCR for SARS\u2010CoV\u20102. Women who were flagged as suspected COVID\u201019 by the questionnaire (questionnaire\u2010positive) were compared with women who were not flagged by the questionnaire (questionnaire\u2010negative).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 446 women were eligible for analysis, of which 54 (12.1%) were questionnaire\u2010positive. PCR swab detected SARS\u2010CoV\u20102 in four (0.9%) women: 3 of 392 (0.8%) in the questionnaire\u2010negative group, and 1 of 54 (1.9%) in the questionnaire\u2010positive group (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.43), yielding a number needed to screen of 92 (95% CI 62\u2010177). In 96% of the cases, the PCR results were obtained only in the postpartum period. No positive PCR results were obtained from neonatal testing for SARS\u2010CoV\u20102. The sensitivity of the questionnaire was 75.0%, and the negative predictive value was 99.7%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although the rate of positive PCR results was not significantly different between the groups, the number needed to screen is considerably high. The use of questionnaire\u2010based PCR testing in areas with low incidence of COVID\u201019 allows for a reasonable allocation of resources and is easy to implement.<\/jats:p><\/jats:sec>","DOI":"10.1111\/birt.12520","type":"journal-article","created":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T02:12:10Z","timestamp":1606875130000},"page":"96-103","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Questionnaire\u2010based vs universal PCR testing for SARS\u2010CoV\u20102 in women admitted for delivery"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4264-9495","authenticated-orcid":false,"given":"Elad","family":"Mei\u2010Dan","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, North York General Hospital University of Toronto  Toronto ON Canada"},{"name":"Division of Maternal\u2010Fetal Medicine Department of Obstetrics and Gynecology Sunnybrook Health Sciences Centre University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abheha","family":"Satkunaratnam","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, North York General Hospital University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tal","family":"Cahan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, North York General Hospital University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian","family":"Leung","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, North York General Hospital University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Katz","sequence":"additional","affiliation":[{"name":"Infection Prevention and Control North York General Hospital University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Aviram","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine Department of Obstetrics and Gynecology Sunnybrook Health Sciences Centre University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"volume-title":"Director\u2010General\u2019s opening remarks at the media briefing on COVID\u201019","author":"World Health Organization (WHO)","key":"e_1_2_6_3_1"},{"volume-title":"Coronavirus COVID\u201019 global cases by Johns Hopkins CSSE","author":"Johns Hopkins University","key":"e_1_2_6_4_1"},{"volume-title":"Rational use of personal protective equipment (PPE) for coronavirus disease (COVID\u201019). Interim Guidance","author":"World Health Organization","key":"e_1_2_6_5_1"},{"volume-title":"Coronavirus disease 2019 (COVID\u201019), Situation Report 73","author":"World Health Organization (WHO)","key":"e_1_2_6_6_1"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.04.024"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2009316"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13191"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.8904"},{"volume-title":"Government of Canada. Coronavirus disease (Covid\u201019): Outbreak update \u2013 current situation","key":"e_1_2_6_11_1"},{"volume-title":"NYSDOH COVID\u201019 Tracker, Department of Health, New\u2010York State","key":"e_1_2_6_12_1"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7154.307"},{"issue":"1","key":"e_1_2_6_14_1","first-page":"e1\u201091.e4","article-title":"Evidence for and against vertical transmission for SARS\u2010CoV\u20102 (COVID\u201019)","volume":"223","author":"Lamouroux A","year":"2020","journal-title":"Am J Obtet Gynecol"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003926"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2020.04.034"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-020-01730-4"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/mi11030306"},{"volume-title":"Coronavirus (COVID\u201019) and Pregnancy: What Maternal\u2010Fetal Medicine Subspecialists Need to Know","author":"Dotters\u2010Katz SK","key":"e_1_2_6_19_1"},{"key":"e_1_2_6_20_1","unstructured":"Centers for Disease Control and Prevention.Evaluating and Reporting Persons Under Investigation (PUI).Centers for Disease Control and Prevention.https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/hcp\/clinical-criteria.html#foot3. Published 2020. Accessed May 12 2020."}],"container-title":["Birth"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/birt.12520","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/birt.12520","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/birt.12520","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T05:28:52Z","timestamp":1693546132000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/birt.12520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/birt.12520"],"URL":"https:\/\/doi.org\/10.1111\/birt.12520","archive":["Portico"],"relation":{},"ISSN":["0730-7659","1523-536X"],"issn-type":[{"type":"print","value":"0730-7659"},{"type":"electronic","value":"1523-536X"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"2020-06-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}