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This large nationwide cohort study evaluates whether exposure to LP can influence obstetric outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed Austrian birth registry data on 717\u00a0113 cases between 2008 and 2016 and excluded cases involving day\u2010time delivery, &lt;23\u00a0+\u00a00 gestational weeks, and\/or birthweight &lt;500\u00a0g, induction of labor, elective cesarean, or cases with missing data. The independent variable, that is, degree of night\u2010time LP, was categorized as low (0.174 to &lt;0.688 mcd\/m<jats:sup>2<\/jats:sup>), medium (0.688 to &lt;3 mcd\/m<jats:sup>2<\/jats:sup>), or high (3 to &lt;10 mcd\/m<jats:sup>2<\/jats:sup>). Duration of labor and adverse neonatal outcomes served as outcome measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cases in regions with high LP (odds ratio [OR], 1.43; 95% confidence interval [CI], 1.30\u20101.57) and medium LP (OR, 1.22; 95% CI, 1.14\u20101.31) showed increased odds of prolonged labor (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001 each). Newborns born in regions with high LP (OR, 1.12; 95% CI, 1.07\u20101.16) and medium LP (OR, 1.07; 95% CI, 1.04\u20101.10) showed increased odds of experiencing adverse outcomes (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001 each). Preterm delivery &lt;28\u00a0+\u00a00\u00a0weeks was also associated with the degree of LP (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.04).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Night\u2010time LP negatively interferes with obstetric outcomes. The perceived influence of LP as an environmental agent needs to be re\u2010evaluated to minimize associated health risks.<\/jats:p><\/jats:sec>","DOI":"10.1111\/birt.12577","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T05:49:52Z","timestamp":1626068992000},"page":"87-96","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Exposure to night\u2010time light pollution and risk of prolonged duration of labor: A nationwide cohort study"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0739-3658","authenticated-orcid":false,"given":"Karin","family":"Windsperger","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Division of Obstetrics and Feto\u2010Maternal Medicine Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"Kiss","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Division of Obstetrics and Feto\u2010Maternal Medicine Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilhelm","family":"Oberaigner","sequence":"additional","affiliation":[{"name":"Department of Public Health, Health Services Research and Health Technology Assessment Institute of Public Health, Medical Decision Making and Health Technology Assessment UMIT University for Health Sciences Medical Informatics and Technology  Hall in Tirol Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermann","family":"Leitner","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology Tyrolean Federal Institute for Integrated Care Tirol Kliniken GmbH  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz","family":"Binder","sequence":"additional","affiliation":[{"name":"Department of Astrophysics University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8981-4817","authenticated-orcid":false,"given":"Dana A.","family":"Muin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Division of Obstetrics and Feto\u2010Maternal Medicine Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8409-1119","authenticated-orcid":false,"given":"Philipp","family":"Foessleitner","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Division of Obstetrics and Feto\u2010Maternal Medicine Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter W.","family":"Husslein","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Division of Obstetrics and Feto\u2010Maternal Medicine Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4628-9052","authenticated-orcid":false,"given":"Alex","family":"Farr","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Division of Obstetrics and Feto\u2010Maternal Medicine Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,11]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Evolutionary Medicine and Health: New Perspectives","author":"Trevathan W","year":"2008"},{"key":"e_1_2_8_3_1","volume-title":"Evolutionary Psychology: A Critical Introduction","author":"Badcock CR","year":"2000"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/07420528.2015.1072002"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1890\/1540-9295(2004)002[0191:ELP]2.0.CO;2"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.117-a20"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/h2020278"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2012.1326"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1600377"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.2164"},{"key":"e_1_2_8_11_1","doi-asserted-by":"crossref","unstructured":"ArgysL AverettYM.Light pollution sleep deprivation and infant health at birth. 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