{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T15:48:18Z","timestamp":1776872898490,"version":"3.51.2"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the epidemiology, clinical management, and outcomes of women with gestational breast cancer (GBC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A population\u2010based prospective cohort study was conducted in Australia and New Zealand between 2013 and 2014 using the Australasian Maternity Outcomes Surveillance System (AMOSS). Women who gave birth with a primary diagnosis of breast cancer during pregnancy were included. Data were collected on demographic and pregnancy factors, GBC diagnosis, obstetric and cancer management, and perinatal outcomes. The main outcome measures were preterm birth, maternal complications, breastfeeding, and death.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty women with GBC (incidence 7.5\/100\u2009000 women giving birth) gave birth to 40 live\u2010born babies. Thirty\u2010three (82.5%) women had breast symptoms at diagnosis. Of 27 women diagnosed before 30\u2009weeks' gestation, 85% had breast surgery and 67% had systemic therapy during pregnancy. In contrast, all 13 women diagnosed from 30\u2009weeks had their cancer management delayed until postdelivery. There were 17 preterm deliveries; 15 were planned. Postpartum complications included the following: hemorrhage (n\u00a0=\u00a04), laparotomy (n\u00a0=\u00a01), and thrombocytopenia (n\u00a0=\u00a01). There was one late maternal death. Eighteen (45.0%) women initiated breastfeeding, including 12 of 23 women who had antenatal breast surgery. There were no perinatal deaths or congenital malformations, but 42.5% of babies were preterm, and 32.5% were admitted for higher\u2010level neonatal care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Gestational breast cancer diagnosed before 30\u2009weeks' gestation was associated with surgical and systemic cancer care during pregnancy and planned preterm birth. In contrast, cancer treatment was deferred to postdelivery for women diagnosed from 30\u2009weeks, reflecting the complexity of managing expectant mothers with GBC in multidisciplinary care settings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/birt.12642","type":"journal-article","created":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T13:21:48Z","timestamp":1650979308000},"page":"763-773","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Perinatal outcomes of women with gestational breast cancer in Australia and New Zealand: A prospective population\u2010based study"],"prefix":"10.1111","volume":"49","author":[{"given":"Elizabeth","family":"Sullivan","sequence":"first","affiliation":[{"name":"College of Health, Medicine and Wellbeing University of Newcastle  Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8473-0980","authenticated-orcid":false,"given":"Nadom","family":"Safi","sequence":"additional","affiliation":[{"name":"College of Health, Medicine and Wellbeing University of Newcastle  Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuoyang","family":"Li","sequence":"additional","affiliation":[{"name":"College of Health, Medicine and Wellbeing University of Newcastle  Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Remond","sequence":"additional","affiliation":[{"name":"College of Health, Medicine and Wellbeing University of Newcastle  Newcastle New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tina Y. T.","family":"Chen","sequence":"additional","affiliation":[{"name":"Faculty of Health University of Technology Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasrin","family":"Javid","sequence":"additional","affiliation":[{"name":"Faculty of Health University of Technology Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan E.","family":"Dickinson","sequence":"additional","affiliation":[{"name":"Faculty of Health and Medical Sciences The University of Western Australia  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Ives","sequence":"additional","affiliation":[{"name":"Faculty of Health and Medical Sciences, Medical School The University of Western Australia  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Hammarberg","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoinette","family":"Anazodo","sequence":"additional","affiliation":[{"name":"School of Women and Children University of New South Wales  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frances","family":"Boyle","sequence":"additional","affiliation":[{"name":"Patricia Ritchie Centre for Cancer Care and Research Mater Hospital Sydney, and University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Fisher","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lesley","family":"Halliday","sequence":"additional","affiliation":[{"name":"School of Public Health and Community Medicine University of New South Wales  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greg","family":"Duncombe","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Centre for Clinical Research University of Queensland  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"McLintock","sequence":"additional","affiliation":[{"name":"National Women's Health Auckland City Hospital  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex Y.","family":"Wang","sequence":"additional","affiliation":[{"name":"Faculty of Health University of Technology Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christobel","family":"Saunders","sequence":"additional","affiliation":[{"name":"Faculty of Health and Medical Sciences The University of Western Australia  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,4,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2015.02.006"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2012.03475.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyx242"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/esmoopen-2015-000016"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3182a057a2"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.17.4110"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181b19154"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2005.02.008"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0245493"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-017713"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002198"},{"issue":"2","key":"e_1_2_8_13_1","first-page":"64","article-title":"The development of a classification system for maternity models of care","volume":"45","author":"Donnolley N","year":"2016","journal-title":"Health Inf Manag"},{"key":"e_1_2_8_14_1","unstructured":"Australian Institute of Health and Welfare.Australia's mothers and babies 2013\u2014in brief. 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