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We also evaluated differences in the influence of various maternal factors associated with PPD in adolescent versus adult mothers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective cohort study using electronic health records linked to birth certificates to evaluate the associations between maternal factors and PPD diagnosis. The study population was stratified into adults and adolescents based on age at delivery. We evaluated socioeconomic, demographic, psychological, and clinical factors associated with PPD in each of the age\u2010defined maternal cohorts using multivariable logistic regression analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 61,226 primiparous women, including 6435 (11%) mothers younger than 20\u2009years old, were included in the study. The overall PPD rate was 4.0%, with the age\u2010specific PPD rate measuring 1.6 times higher in adolescents than in adult women (6.1% vs. 3.8%). Compared with adults, adolescents were less likely to obtain firsttrimester prenatal care (33% vs. 16%), more likely to have recent tobacco use (11% vs. 6%), and more likely to have had an infection during pregnancy (5% vs. 1%). In adjusted models, significant factors for PPD in both groups included a history of depression or anxiety, tobacco use, and long\u2010acting reversible contraception use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this cohort of first\u2010time mothers, adolescents had higher rates of PPD diagnosis as well as PPD\u2010associated maternal factors than adults. Increased awareness of PPD risk in adolescents and early intervention, including integrating mental healthcare into prenatal care, may help benefit adolescents and reduce the risk and severity of PPD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/birt.12785","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T07:24:54Z","timestamp":1697613894000},"page":"218-228","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparing maternal factors associated with postpartum depression between primiparous adolescents and adults: A\u00a0large retrospective cohort study"],"prefix":"10.1111","volume":"51","author":[{"given":"Nakyung","family":"Jeon","sequence":"first","affiliation":[{"name":"College of Pharmacy and Research Institute for Drug Development Pusan National University  Busan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Kent\u2010Marvick","sequence":"additional","affiliation":[{"name":"College of Nursing University of Utah  Salt Lake City Utah USA"},{"name":"Interdisciplinary Training in Cancer, Caregiving &amp; 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