{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T13:17:01Z","timestamp":1774617421927,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T00:00:00Z","timestamp":1727654400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>While some labor interventions are essential in preventing maternal and neonatal morbidity, there is little evidence to support systematic early augmentation of labor (EAL). Our objective was to assess the association between EAL and cesarean delivery rate, postpartum hemorrhage and adverse neonatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Population\u2010based study using data from the 2016 French Perinatal Survey. Women with a singleton cephalic fetus, delivering at term after a spontaneous labor were included. \u201cEAL\u201d was defined by artificial rupture of the membranes (AROM) and\/or oxytocin within 1\u2009h of admission and\/or duration between interventions of less than 1\u2009h. Women without EAL were women without labor augmentation or without EAL. The primary endpoint, cesarean delivery and the secondary endpoints were compared between women with and without EAL using univariate analysis. A multivariable logistic regression was adjusted on the suspected confounders and a propensity score approach was then performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 7196 women included, 1524 (21.2%) had EAL. Cesarean delivery rates were significantly higher in the EAL group compared with the no EAL group, 8.40% versus 6.15% (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). EAL was associated with cesarean delivery in the multivariable analysis aOR 1.45 95% CI [1.15\u20131.82] and in the cohort matched on the propensity score, OR 1.56 [1.17\u20132.07]. EAL was not associated with severe postpartum hemorrhage, low 5\u2010min Apgar score, low neonatal cord pH or transfer to NICU.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>EAL is frequent, involving one in five spontaneous laboring women in France. This practice is associated with an increased cesarean delivery risk.<\/jats:p><\/jats:sec>","DOI":"10.1111\/birt.12883","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T05:08:27Z","timestamp":1727759307000},"page":"308-319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Maternal and Neonatal Consequences of Early Augmentation of Labor Among Women With Spontaneous Onset of Labor: A National Population\u2010Based Study"],"prefix":"10.1111","volume":"52","author":[{"given":"Aude","family":"Girault","sequence":"first","affiliation":[{"name":"INSERM UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epop\u00e9), Center for Epidemiology and Statistics, FHU PREMA Universit\u00e9 de Paris  Paris France"},{"name":"H\u00f4pital Cochin Port Royal, Maternit\u00e9 Port Royal, Assistance Publique\u2010H\u00f4pitaux de Paris Universit\u00e9 de Paris  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e9atrice","family":"Blondel","sequence":"additional","affiliation":[{"name":"INSERM UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epop\u00e9), Center for Epidemiology and Statistics, FHU PREMA Universit\u00e9 de Paris  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Fraser","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Sherbrooke  Sherbrooke Canada"},{"name":"Centre de Recherche du Centre Hospitalier, Universitaire de Sherbrooke (CRCHUS)  Sherbrooke Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Goffinet","sequence":"additional","affiliation":[{"name":"INSERM UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epop\u00e9), Center for Epidemiology and Statistics, FHU PREMA Universit\u00e9 de Paris  Paris France"},{"name":"H\u00f4pital Cochin Port Royal, Maternit\u00e9 Port Royal, Assistance Publique\u2010H\u00f4pitaux de Paris Universit\u00e9 de Paris  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camille","family":"Le Ray","sequence":"additional","affiliation":[{"name":"INSERM UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epop\u00e9), Center for Epidemiology and Statistics, FHU PREMA Universit\u00e9 de Paris  Paris France"},{"name":"H\u00f4pital Cochin Port Royal, Maternit\u00e9 Port Royal, Assistance Publique\u2010H\u00f4pitaux de Paris Universit\u00e9 de Paris  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.srhc.2009.09.001"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1363459313476964"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wombi.2018.04.010"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016340903358812"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2017.08.012"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1891\/1058-1243.23.1.9"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2017.09.002"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5655.477"},{"issue":"7","key":"e_1_2_10_10_1","article-title":"Continuous Support for Women During Childbirth","volume":"7","author":"Bohren M. A.","year":"2017","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.05.072"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)09409-9"},{"issue":"9","key":"e_1_2_10_13_1","article-title":"Package of Care for Active Management in Labour for Reducing Caesarean Section Rates in Low\u2010Risk Women","author":"Brown H. C.","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199509213331201"},{"issue":"8","key":"e_1_2_10_15_1","article-title":"Early Amniotomy and Early Oxytocin for Prevention of, or Therapy for, Delay in First Stage Spontaneous Labour Compared With Routine Care","author":"Wei S.","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgyn.2013.02.011"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.12.015"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1997.tb11530.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-3782(92)90183-H"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1996.tb09734.x"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(87)80288-0"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.01.026"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g6886"},{"key":"e_1_2_10_24_1","unstructured":"Haute Autorit\u00e9 de Sant\u00e9 \u201cAccouchement Normal: Accompagnement de la Physiologie et Interventions M\u00e9dicales \u201d2018."},{"key":"e_1_2_10_25_1","unstructured":"The WHO Reproductive Health Library; Geneva: World Health Organization \u201cWHO Recommendation on Duration of the First Stage of Labour \u201d2018."},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2017.04.010"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb09362.x"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healthplace.2011.06.002"},{"key":"e_1_2_10_29_1","volume-title":"Internet 2020 In: StatPearls Internet","author":"Gillam\u2010Krakauer M.","year":"2020"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016340601181318"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.midw.2013.03.010"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/tog.12222"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.midw.2021.103238"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-536X.2012.00547.x"},{"key":"e_1_2_10_35_1","unstructured":"World Health Organization \u201cRecommendation on Application of Slow\u2010yet\u2010Normal Cervical Dilatation Patterns for Labour Management \u201d2018."}],"container-title":["Birth"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/birt.12883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T12:13:37Z","timestamp":1746706417000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/birt.12883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,30]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/birt.12883"],"URL":"https:\/\/doi.org\/10.1111\/birt.12883","archive":["Portico"],"relation":{},"ISSN":["0730-7659","1523-536X"],"issn-type":[{"value":"0730-7659","type":"print"},{"value":"1523-536X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,30]]},"assertion":[{"value":"2021-10-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}