{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T07:02:01Z","timestamp":1790060521324,"version":"4.0.1"},"reference-count":63,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["P50MH115846"],"award-info":[{"award-number":["P50MH115846"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["K23DA050808"],"award-info":[{"award-number":["K23DA050808"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["F31DA052994"],"award-info":[{"award-number":["F31DA052994"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bpspsychub.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["British J Clinic Psychol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>A history of trauma is common among people with psychotic disorders, and such a history is associated with more severe symptoms. Men and women with psychosis often experience differences in their course of illness and symptom profiles. Although past work has found gender differences in trauma among those with first episode psychosis, data in this domain are limited and primarily focused on childhood trauma with cross\u2010sectional designs. The current analysis examined the relationship between lifetime trauma exposure at baseline and changes in functioning and symptom severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Secondary data analysis from the Recovery After an Initial Episode of Schizophrenia\u2013Early Treatment Program (RAISE\u2010ETP) study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Four hundred participants (27% female) completed assessments at 6\u2010month intervals over 24 months that were analysed cross\u2010sectionally and longitudinally by high\/low trauma exposure and gender.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Results suggested that gender differences exist in the relationship between trauma exposure and symptoms for individuals with first episode psychosis. Cross\u2010sectionally at baseline, more reported trauma was related to greater symptom severity for both men and women and most significantly related to depression. However, over the first 2\u2009years of treatment, women with a greater history of trauma demonstrated significantly less improvement in psychotic symptoms than those with less trauma, whereas trauma history in men was not related to clinical improvement. Similar gender differences in improved psychotic symptoms were found when history of childhood sexual trauma was examined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Overall, the findings indicate that clinical interventions should systematically assess and address lifetime trauma exposure in first episode psychosis care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial Registration<\/jats:title>\n                    <jats:p>\n                      The overall RAISE\u2010ETP study is registered on\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link>\n                      NCT#: NCT01321177.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bjc.70099","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T06:09:40Z","timestamp":1790057380000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal effects of lifetime trauma exposure and childhood sexual trauma by gender in individuals with first episode psychosis"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8302-6286","authenticated-orcid":false,"given":"Julie M.","family":"McCarthy","sequence":"first","affiliation":[{"name":"Division of Psychotic Disorders McLean Hospital  Belmont Massachusetts USA"},{"name":"Department of Psychiatry Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0648-322X","authenticated-orcid":false,"given":"Jacqueline F.","family":"Dow","sequence":"additional","affiliation":[{"name":"Division of Psychotic Disorders McLean Hospital  Belmont Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin M.","family":"Shepherd","sequence":"additional","affiliation":[{"name":"Division of Psychotic Disorders McLean Hospital  Belmont Massachusetts USA"},{"name":"Department of Psychology University of Houston  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1482-8314","authenticated-orcid":false,"given":"Kim T.","family":"Mueser","sequence":"additional","affiliation":[{"name":"Department of Occupational Therapy Boston University  Boston Massachusetts USA"},{"name":"Department of Psychological and Brain Sciences Boston University  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888\u2010016\u20100827\u20104"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2011.03.017"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2022.115045"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1192\/S0007125000292581"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201400124"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2015.04.022"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpsy.2014.08.005"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2021.114272"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2215\u20100366(22)00337\u20106"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.110.083642"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0004867411430877"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/s2215\u20100366(21)00383\u20107"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1037\/0021\u2010843X.116.3.607"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2018.12.046"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2019.112507"},{"issue":"1","key":"e_1_2_12_17_1","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.schres.2010.01.032","article-title":"Rate and predictors of service disengagement in an epidemiological first\u2010episode psychosis cohort","volume":"118","author":"Conus P.","year":"2010","journal-title":"Schizophrenia Research"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291719001016"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291716001094"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1037\/ser0000380"},{"key":"e_1_2_12_21_1","volume-title":"Structured Clinical Interview for DSM\u2010IV\u00ae Axis I Disorders (SCID\u2010I), Clinician Version, administration booklet","author":"First M. B.","year":"2012"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.107.047985"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2016.04.004"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/eip.12315"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/10.3.388"},{"key":"e_1_2_12_26_1","unstructured":"Heinssen R. K. Goldstein A. B. &Azrin S. T.(2014).Evidence\u2010based treatments for first episode psychosis: Components of coordinated specialty care.https:\/\/www.nimh.nih.gov\/health\/topics\/schizophrenia\/raise\/evidence\u2010based\u2010treatments\u2010for\u2010first\u2010episode\u2010psychosis\u2010components\u2010of\u2010coordinated\u2010specialty\u2010care"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpm.12889"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/eip.13367"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbr085"},{"issue":"4","key":"e_1_2_12_30_1","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1176\/appi.ajp.2015.15050632","article-title":"Comprehensive versus usual community care for first\u2010episode psychosis: 2\u2010year outcomes from the NIMH RAISE early treatment program","volume":"173","author":"Kane J. M.","year":"2016","journal-title":"American Journal of Psychiatry"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.14m09289"},{"issue":"2","key":"e_1_2_12_32_1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The Positive and Negative Syndrome Scale (PANSS) for schizophrenia","volume":"13","author":"Kay S. R.","year":"1987","journal-title":"Schizophrenia Bulletin"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/20008198.2017.1353383"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2020.113004"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291711000973"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00127\u2010008\u20100384\u20103"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1037\/1040\u20103590.12.2.210"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2004.11.009"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2024.3426"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215\u20100366(16)30358\u20103"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10597\u2010009\u20109248\u2010x"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2024.10.022"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.prcp.20220028"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2015.12.003"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737\u2010023\u201001409\u2010x"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2009.10.025"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201400413"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2006.09.005"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10597\u2010021\u201000916\u20104"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbw082"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2022.02.039"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2018.06.043"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/inm.12369"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbz030"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2011.13.2\/ischaefer"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2008.03.006"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.154.12.1641"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1108\/JCP\u201002\u20102015\u20100009"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpsy.2013.02.006"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbt166"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2018.04.010"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbs050"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2020.11.047"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2012.01.031"}],"container-title":["British Journal of Clinical Psychology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bpspsychub.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjc.70099","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bpspsychub.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bjc.70099","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bpspsychub.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjc.70099","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T06:09:44Z","timestamp":1790057384000},"score":1,"resource":{"primary":{"URL":"https:\/\/bpspsychub.onlinelibrary.wiley.com\/doi\/10.1111\/bjc.70099"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,21]]},"references-count":63,"alternative-id":["10.1111\/bjc.70099"],"URL":"https:\/\/doi.org\/10.1111\/bjc.70099","archive":["Portico"],"relation":{},"ISSN":["0144-6657","2044-8260"],"issn-type":[{"value":"0144-6657","type":"print"},{"value":"2044-8260","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,21]]},"assertion":[{"value":"2026-05-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"bjc.70099"}}