{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T19:08:45Z","timestamp":1780945725441,"version":"3.54.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100009947","name":"Merck Sharp & Dohme Corp.","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100009947","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,3,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Existing tools for nail psoriasis are complex and may not adequately measure outcomes that are important to patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We have developed and validated a new tool, the Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA), with three components: a questionnaire assessing quality of life (NAPPA-QoL), a two-part questionnaire assessing patient-relevant treatment benefits (the Patient Benefit Index, NAPPA-PBI) and a psoriasis Clinical Assessment of Severity (NAPPA-CLIN).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Development of the questionnaires involved multiple steps: (i) collection of items about nail psoriasis-related impairments and treatment goals; (ii) selection of 48 items by an expert panel, including patients; (iii) translation into eight languages; (iv) feasibility testing and (v) longitudinal validation in six countries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients found the questionnaires clear (84%) and comprehensible (95%). NAPPA-QoL and NAPPA-PBI scores correlated moderately with clinical outcomes [e.g. Nail Psoriasis Severity Index (NAPSI)] and markedly with other quality-of-life questionnaires (e.g. EQ-5D\u2122). Both questionnaires were sensitive to change. Internal consistency was good (Cronbach \u03b1 \u2265 0\u00b788 for all scales). The NAPPA-CLIN, a brief version of NAPSI that involves assessment of only four digits rather than all 20, was found to correlate highly with total NAPSI score (r =0\u00b797, P &amp;lt;0\u00b7001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Overall, the three-component NAPPA tool is a valid, reliable and practical instrument to assess patient-relevant nail psoriasis outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/bjd.12664","type":"journal-article","created":{"date-parts":[[2013,10,14]],"date-time":"2013-10-14T11:59:01Z","timestamp":1381751941000},"page":"591-598","source":"Crossref","is-referenced-by-count":58,"title":["Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA): development and validation of a tool for assessment of nail psoriasis outcomes"],"prefix":"10.1093","volume":"170","author":[{"given":"M.","family":"Augustin","sequence":"first","affiliation":[{"name":"University Medical Center Hamburg-Eppendorf Institute for Health Services Research in Dermatology and Nursing Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Blome","sequence":"additional","affiliation":[{"name":"University Medical Center Hamburg-Eppendorf Institute for Health Services Research in Dermatology and Nursing Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Costanzo","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Rome \u2018Tor Vergata\u2019 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Dauden","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitario de la Princesa Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Ferrandiz","sequence":"additional","affiliation":[{"name":"Servicio de Dermatolog\u00eda Hospital Universitari Germans Trias i Pujol Universitat Aut\u00f2noma de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Girolomoni","sequence":"additional","affiliation":[{"name":"Clinica Dermatologica Universit\u00e0 di Verona Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Gniadecki","sequence":"additional","affiliation":[{"name":"Bispebjerg Hospital University of Copenhagen Copenhagen NV Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Iversen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Aarhus University Hospital Aarhus C Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Menter","sequence":"additional","affiliation":[{"name":"Baylor Research Institute Baylor University Medical Center Dallas TX U.S.A"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Michaelis-Wittern","sequence":"additional","affiliation":[{"name":"SCIderm GmbH Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Morita","sequence":"additional","affiliation":[{"name":"Department of Geriatric and Environmental Dermatology Nagoya City University Graduate School of Medical Sciences Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Department of Dermatology The Jikei University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Reich","sequence":"additional","affiliation":[{"name":"Dermatologikum Hamburg Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,3,1]]},"reference":[{"key":"2023083116072178400_bjd12664-bib-0001","first-page":"174","article-title":"Nail 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