{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T20:18:26Z","timestamp":1774383506007,"version":"3.50.1"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":187,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Dermatol"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1111\/bjd.13412","type":"journal-article","created":{"date-parts":[[2014,9,19]],"date-time":"2014-09-19T01:48:59Z","timestamp":1411091339000},"page":"976-980","source":"Crossref","is-referenced-by-count":23,"title":["Cross-elicitation responses to 2-methoxymethyl-<i>p<\/i>-phenylenediamine under hair dye use conditions in<i>p<\/i>-phenylenediamine-allergic individuals"],"prefix":"10.1093","volume":"172","author":[{"given":"B.","family":"Bl\u00f6meke","sequence":"first","affiliation":[{"name":"Department of Environmental Toxicology; University Trier; Universit\u00e4tsring 15, 54296 Trier Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.M.","family":"Pot","sequence":"additional","affiliation":[{"name":"Dermatology Department; University Medical Center Groningen; University of Groningen; Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.-J.","family":"Coenraads","sequence":"additional","affiliation":[{"name":"Dermatology Department; University Medical Center Groningen; University of Groningen; Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Hennen","sequence":"additional","affiliation":[{"name":"Department of Environmental Toxicology; University Trier; Universit\u00e4tsring 15, 54296 Trier Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Kock","sequence":"additional","affiliation":[{"name":"The Procter & Gamble Co.; Central Product Safety; Darmstadt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Goebel","sequence":"additional","affiliation":[{"name":"The Procter & Gamble Co.; Central Product Safety; Darmstadt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2015,2,26]]},"reference":[{"key":"10.1111\/bjd.13412-BIB0001|bjd13412-cit-0001","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.taap.2013.11.016","article-title":"Introduction of a methoxymethyl side chain into p-phenylenediamine attenuates its sensitizing potency and reduces the risk of allergy induction","volume":"274","author":"Goebel","year":"2014","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1111\/bjd.13412-BIB0002|bjd13412-cit-0002","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0143-7208(98)00075-8","article-title":"An historical review of the use of dye precursors in the formulation of commercial oxidation hair dyes","volume":"41","author":"Corbett","year":"1999","journal-title":"Dyes Pigm"},{"key":"10.1111\/bjd.13412-BIB0003|bjd13412-cit-0003","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1016\/S0278-6915(03)00223-0","article-title":"Classification of contact allergens according to potency: proposals","volume":"41","author":"Kimber","year":"2003","journal-title":"Food Chem Toxicol"},{"key":"10.1111\/bjd.13412-BIB0004|bjd13412-cit-0004","volume-title":"Memorandum on Hair Dye Chemical Sensitisation","author":"Scientific Committee on Consumer Safety","year":"2013"},{"key":"10.1111\/bjd.13412-BIB0005|bjd13412-cit-0005","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/cod.12077","article-title":"Contact allergy to common ingredients in hair dyes","volume":"69","author":"S\u00f8sted","year":"2013","journal-title":"Contact Dermatitis"},{"key":"10.1111\/bjd.13412-BIB0006|bjd13412-cit-0006","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1159\/000247895","article-title":"Study on cross-reactivity to the para group","volume":"181","author":"Picardo","year":"1990","journal-title":"Dermatologica"},{"key":"10.1111\/bjd.13412-BIB0007|bjd13412-cit-0007","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1034\/j.1600-0536.2003.00049.x","article-title":"High frequency of simultaneous sensitivity to disperse orange 3 in patients with positive patch tests to para-phenylenediamine","volume":"48","author":"Goon","year":"2003","journal-title":"Contact Dermatitis"},{"key":"10.1111\/bjd.13412-BIB0008|bjd13412-cit-0008","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.yrtph.2012.10.004","article-title":"Quantitative risk assessment for skin sensitisation: consideration of a simplified approach for hair dye ingredients","volume":"64","author":"Goebel","year":"2012","journal-title":"Regul Toxicol Pharmacol"},{"key":"10.1111\/bjd.13412-BIB0009|bjd13412-cit-0009","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1600-0536.2011.01916.x","article-title":"Patch testing with hydroxyethyl-p-phenylenediamine sulfate - cross-reactivity with p-phenylenediamine","volume":"65","author":"Frosch","year":"2011","journal-title":"Contact Dermatitis"},{"key":"10.1111\/bjd.13412-BIB0010|bjd13412-cit-0010","volume-title":"Opinion on: Hydroxyethyl-p-Phenylenediamine Sulfate COLIPA n\u00b0 A80","author":"Scientific Committee on Consumer Safety","year":"2010"},{"key":"10.1111\/bjd.13412-BIB0011|bjd13412-cit-0011","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1111\/j.0022-202X.2004.22402.x","article-title":"Characterization of the sensitizing potential of chemicals by in vitro analysis of dendritic cell activation and skin penetration","volume":"122","author":"Aeby","year":"2004","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.13412-BIB0012|bjd13412-cit-0012","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1006\/taap.2000.9095","article-title":"The time-dose-response relationship for elicitation of contact dermatitis in isoeugenol allergic individuals","volume":"170","author":"Andersen","year":"2001","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1111\/bjd.13412-BIB0013|bjd13412-cit-0013","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1600-0536.2008.01347.x","article-title":"Elicitation response characteristics to mono- and to n, n\u2032-diacetyl-para-phenylenediamine","volume":"58","author":"Bl\u00f6meke","year":"2008","journal-title":"Contact Dermatitis"},{"key":"10.1111\/bjd.13412-BIB0014|bjd13412-cit-0014","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/cod.12032","article-title":"Penetration and haptenation of p-phenylenediamine","volume":"68","author":"Pot","year":"2013","journal-title":"Contact Dermatitis"},{"key":"10.1111\/bjd.13412-BIB0015|bjd13412-cit-0015","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1016\/j.fct.2004.06.017","article-title":"Thresholds of elicitation depend on induction conditions. Could low level exposure induce sub-clinical allergic states that are only elicited under the severe conditions of clinical diagnosis?","volume":"42","author":"Hostynek","year":"2004","journal-title":"Food Chem Toxicol"},{"key":"10.1111\/bjd.13412-BIB0016|bjd13412-cit-0016","volume-title":"Manual of Contact Dermatitis","author":"Fregert","year":"1981"},{"key":"10.1111\/bjd.13412-BIB0017|bjd13412-cit-0017","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1111\/j.1365-2133.2010.10009.x","article-title":"Elicitation of the immune response to p-phenylenediamine in allergic patients: the role of dose and exposure time","volume":"163","author":"Goebel","year":"2010","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.13412-BIB0018|bjd13412-cit-0018","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1111\/bjd.13142","article-title":"Assessment of the elicitation response in subjects weakly sensitized to p-phenylenediamine","volume":"172","author":"Pot","year":"2014","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.13412-BIB0019|bjd13412-cit-0019","volume-title":"Opinion on: 2-Methylresorcinol COLIPA n\u00b0 A44","author":"Scientific Committee on Consumer Products","year":"2008"},{"key":"10.1111\/bjd.13412-BIB0020|bjd13412-cit-0020","volume-title":"Opinion on: 2-Methyl-5-Hydroxyethylaminophenol COLIPA n\u00b0 A31","author":"Scientific Committee on Consumer Products","year":"2006"},{"key":"10.1111\/bjd.13412-BIB0021|bjd13412-cit-0021","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1600-0536.2008.01416.x","article-title":"Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances","volume":"59","author":"Skazik","year":"2008","journal-title":"Contact Dermatitis"},{"key":"10.1111\/bjd.13412-BIB0022|bjd13412-cit-0022","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/j.1365-2133.2008.08644.x","article-title":"Para-phenylenediamine: the profile of an important allergen. Results of the IVDK","volume":"159","author":"Schnuch","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.13412-BIB0023|bjd13412-cit-0023","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1600-0536.1998.tb05837.x","article-title":"The effect of patch duration on the elicitation of para-phenylenediamine contact allergy","volume":"39","author":"McFadden","year":"1998","journal-title":"Contact Dermatitis"},{"key":"10.1111\/bjd.13412-BIB0024|bjd13412-cit-0024","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1034\/j.1600-0536.2002.470207.x","article-title":"Dose-time relationships for elicitation of contact allergy to para-phenylenediamine","volume":"47","author":"Hextall","year":"2002","journal-title":"Contact Dermatitis"},{"key":"10.1111\/bjd.13412-BIB0025|bjd13412-cit-0025","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/s13238-012-2077-7","article-title":"Recognition of self and altered self by T cells in autoimmunity and allergy","volume":"4","author":"Yin","year":"2013","journal-title":"Protein Cell"},{"key":"10.1111\/bjd.13412-BIB0026|bjd13412-cit-0026","first-page":"50","article-title":"Studies on the question of cross-allergenicity of amino- and nitro-substituted aromatic compounds","volume":"43","author":"Hoting","year":"1995","journal-title":"Derm Beruf Umwelt"},{"key":"10.1111\/bjd.13412-BIB0027|bjd13412-cit-0027","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/s002040050293","article-title":"Evaluation of cross-sensitization among dye-intermediate agents using a modified lymphocyte transformation test","volume":"70","author":"Li","year":"1996","journal-title":"Arch Toxicol"},{"key":"10.1111\/bjd.13412-BIB0028|bjd13412-cit-0028","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1002\/1521-4141(200205)32:5<1338::AID-IMMU1338>3.0.CO;2-4","article-title":"Cross-sensitization to haptens: formation of common haptenic metabolites, T cell recognition of cryptic peptides, and true T cell cross-reactivity","volume":"32","author":"Wulferink","year":"2002","journal-title":"Eur J Immunol"},{"key":"10.1111\/bjd.13412-BIB0029|bjd13412-cit-0029","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1600-0536.1997.tb00420.x","article-title":"Cross-sensitizations between azo dyes and para-amino compound. A study of 236 azo-dye-sensitive subjects","volume":"36","author":"Seidenari","year":"1997","journal-title":"Contact Dermatitis"},{"key":"10.1111\/bjd.13412-BIB0030|bjd13412-cit-0030","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1034\/j.1600-0536.2000.042005270.x","article-title":"Experimental study on skin sensitization potencies and cross-reactivities of hair-dye-related chemicals in guinea pigs","volume":"42","author":"Xie","year":"2000","journal-title":"Contact Dermatitis"},{"key":"10.1111\/bjd.13412-BIB0031|bjd13412-cit-0031","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1021\/tx900095r","article-title":"A mechanistic investigation into the irreversible protein binding and antigenicity of p-phenylenediamine","volume":"22","author":"Jenkinson","year":"2009","journal-title":"Chem Res Toxicol"},{"key":"10.1111\/bjd.13412-BIB0032|bjd13412-cit-0032","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1111\/j.1365-2133.2009.09352.x","article-title":"Para-phenylenediamine and allergic sensitization: risk modification by N-acetyltransferase 1 and 2 genotypes","volume":"161","author":"Bl\u00f6meke","year":"2009","journal-title":"Br J Dermatol"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbjd.13412","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/bjd.13412\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T14:12:16Z","timestamp":1676383936000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/172\/4\/976\/6616281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,26]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"URL":"https:\/\/doi.org\/10.1111\/bjd.13412","relation":{},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2,26]]}}}