{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T20:51:34Z","timestamp":1785876694861,"version":"3.56.0"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2015,10,29]],"date-time":"2015-10-29T00:00:00Z","timestamp":1446076800000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Dermatol"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1111\/bjd.14040","type":"journal-article","created":{"date-parts":[[2015,10,29]],"date-time":"2015-10-29T09:11:25Z","timestamp":1446109885000},"page":"896-909","source":"Crossref","is-referenced-by-count":19,"title":["Diphenylcyclopropenone in patients with alopecia areata. A critically appraised topic"],"prefix":"10.1093","volume":"173","author":[{"given":"R.A.","family":"Kuin","sequence":"first","affiliation":[{"name":"Dutch Association for Dermatology and Venereology (NVDV); Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.I.","family":"Spuls","sequence":"additional","affiliation":[{"name":"Dermatology Department; Academic Medical Center; Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Limpens","sequence":"additional","affiliation":[{"name":"Academic Medical Center; Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. J.","family":"van Zuuren","sequence":"additional","affiliation":[{"name":"Dermatology Department; Leiden University Medical Center; Leiden the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2015,10,29]]},"reference":[{"key":"10.1111\/bjd.14040-BIB0001|bjd14040-cit-0001","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1056\/NEJMra1103442","article-title":"Alopecia areata","volume":"366","author":"Gilhar","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1111\/bjd.14040-BIB0002|bjd14040-cit-0002","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1038\/jid.2013.464","article-title":"Lifetime incidence risk of alopecia areata estimated at 2.1% by Rochester Epidemiology Project, 1990-2009","volume":"134","author":"Mirzoyev","year":"2014","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.14040-BIB0003|bjd14040-cit-0003","doi-asserted-by":"crossref","first-page":"c3671","DOI":"10.1136\/bmj.c3671","article-title":"Management of alopecia areata","volume":"341","author":"Harries","year":"2010","journal-title":"BMJ"},{"key":"10.1111\/bjd.14040-BIB0004|bjd14040-cit-0004","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1111\/j.1365-2133.2012.10955.x","article-title":"British Association of Dermatologists\u2019 guidelines for the management of alopecia areata 2012","volume":"166","author":"Messenger","year":"2012","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.14040-BIB0005|bjd14040-cit-0005","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1046\/j.1365-2133.2001.04399.x","article-title":"The therapeutic use of topical contact sensitizers in benign dermatoses","volume":"145","author":"Buckley","year":"2001","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.14040-BIB0006|bjd14040-cit-0006","first-page":"167","article-title":"Resultaten enquet\u00ea diphencyprone bij alopecia areata","volume":"25","author":"Kuin","year":"2015","journal-title":"NTvDV"},{"key":"10.1111\/bjd.14040-BIB0007|bjd14040-cit-0007","unstructured":"GRADE working group GRADE http:\/\/www.gradeworkinggroup.org"},{"key":"10.1111\/bjd.14040-BIB0008|bjd14040-cit-0008","unstructured":"Alopecia Vereniging Focus group session with president of Dutch Alopecia patient society www.alopecia-vereniging.nl"},{"key":"10.1111\/bjd.14040-BIB0009|bjd14040-cit-0009","unstructured":"Higgins JPT Green S Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0 http:\/\/www.cochrane-handbook.org"},{"key":"10.1111\/bjd.14040-BIB0010|bjd14040-cit-0010","unstructured":"GRADEproGDT A new quality in guideline development http:\/\/www.guidelinedevelopment.org"},{"key":"10.1111\/bjd.14040-BIB0011|bjd14040-cit-0011","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1136\/bmj.328.7454.1490","article-title":"Grading quality of evidence and strength of recommendations","volume":"328","author":"Grade working group","year":"2004","journal-title":"BMJ"},{"key":"10.1111\/bjd.14040-BIB0012|bjd14040-cit-0012","first-page":"A4379","article-title":"[Guidelines are made more transparent with the GRADE method: considerations for recommendations are explicit in the new method]","volume":"156","author":"Boluyt","year":"2012","journal-title":"Ned Tijdschr Geneeskd"},{"key":"10.1111\/bjd.14040-BIB0013|bjd14040-cit-0013","unstructured":"Sch\u00fcnemann H Brozek J Guyatt G Oxman A GRADE Handbook http:\/\/www.guidelinedevelopment.org\/handbook"},{"key":"10.1111\/bjd.14040-BIB0014|bjd14040-cit-0014","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/j.1365-2133.1996.tb03835.x","article-title":"Alopecia areata in children: treatment with diphencyprone","volume":"135","author":"Schuttelaar","year":"1996","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.14040-BIB0015|bjd14040-cit-0015","first-page":"5","article-title":"Topical immunotherapy of severe AA with diphenylcyclopropenone (DPCP): experience in an Iranian population","volume":"26","author":"Aghaei","year":"2005","journal-title":"BMC Dermatol"},{"key":"10.1111\/bjd.14040-BIB0016|bjd14040-cit-0016","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/j.1365-2133.1989.tb04166.x","article-title":"Allergic and irritant contact dermatitis compared in the treatment of alopecia totalis and universalis. A comparison of the value of topical diphencyprone and tretinoin gel","volume":"120","author":"Ashworth","year":"1989","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.14040-BIB0017|bjd14040-cit-0017","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1111\/j.1468-3083.2007.02411.x","article-title":"Alopecia areata: topical immunotherapy treatment with diphencyprone","volume":"22","author":"Avgerinou","year":"2008","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1111\/bjd.14040-BIB0018|bjd14040-cit-0018","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1365-2230.1991.tb00339.x","article-title":"Treatment of alopecia totalis with a combination of inosine pranobex and diphencyprone compared to each treatment alone","volume":"16","author":"Berth-Jones","year":"1991","journal-title":"Clin Exp Dermatol"},{"key":"10.1111\/bjd.14040-BIB0019|bjd14040-cit-0019","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1067\/mjd.2001.109309","article-title":"The use of topical diphenylcyclopropenone for the treatment of extensive alopecia areata","volume":"44","author":"Cotellessa","year":"2001","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.14040-BIB0020|bjd14040-cit-0020","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1468-3083.2004.01138.x","article-title":"Topical immunotherapy with diphencyprone in the treatment of extensive and\/or long-lasting alopecia areata","volume":"19","author":"Firooz","year":"2005","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1111\/bjd.14040-BIB0021|bjd14040-cit-0021","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1111\/j.1365-2133.1996.tb06317.x","article-title":"Topical diphencyprone for alopecia areata: evaluation of 48 cases after 30\u00a0months\u2019 follow-up","volume":"134","author":"Gordon","year":"1996","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.14040-BIB0022|bjd14040-cit-0022","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1365-2230.1989.tb00915.x","article-title":"Induction of hair growth in alopecia totalis with diphencyprone sensitization","volume":"14","author":"Monk","year":"1989","journal-title":"Clin Exp Dermatol"},{"key":"10.1111\/bjd.14040-BIB0023|bjd14040-cit-0023","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0190-9622(91)70037-3","article-title":"Treatment of alopecia areata with diphenylcyclopropenone","volume":"24","author":"Steen","year":"1991","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.14040-BIB0024|bjd14040-cit-0024","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1159\/000247540","article-title":"Topical immunotherapy for alopecia areata: re-evaluation of 139 cases after an additional follow-up period of 19\u00a0months","volume":"184","author":"Steen","year":"1992","journal-title":"Dermatology"},{"key":"10.1111\/bjd.14040-BIB0025|bjd14040-cit-0025","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3109\/09546630903410182","article-title":"Diphencyprone and topical tacrolimus as two topical immunotherapeutic modalities. Are they effective in the treatment of alopecia areata among Egyptian patients? A study using CD4, CD8 and MHC II as markers","volume":"22","author":"Hunter","year":"2011","journal-title":"J Dermatolog Treat"},{"key":"10.1111\/bjd.14040-BIB0026|bjd14040-cit-0026","first-page":"CD004413","article-title":"Interventions for alopecia areata","volume":"2","author":"Delamere","year":"2008","journal-title":"Cochrane Database Syst Rev"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbjd.14040","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbjd.14040","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/bjd.14040\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T14:16:53Z","timestamp":1676384213000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/173\/4\/896\/6616010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,10]]}},"URL":"https:\/\/doi.org\/10.1111\/bjd.14040","archive":["Portico"],"relation":{},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]}}}