{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T23:38:21Z","timestamp":1779233901939,"version":"3.51.4"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"name":"Photocure ASA"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Dermatol"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1111\/bjd.14345","type":"journal-article","created":{"date-parts":[[2015,12,13]],"date-time":"2015-12-13T13:42:49Z","timestamp":1450014169000},"page":"770-777","source":"Crossref","is-referenced-by-count":38,"title":["Photodynamic therapy with methyl aminolaevulinate 80 mg g<sup>\u22121<\/sup>for severe facial acne vulgaris: a randomized vehicle-controlled study"],"prefix":"10.1093","volume":"174","author":[{"given":"D.M.","family":"Pariser","sequence":"first","affiliation":[{"name":"Eastern Virginia Medical School; Division of Dermatology, and Virginia Clinical Research Inc.; 6161 Kempsville Circle Suite 200A Norfolk VA 23502 U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.F.","family":"Eichenfield","sequence":"additional","affiliation":[{"name":"Rady Children's Hospital San Diego and University of California; San Diego CA U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Bukhalo","sequence":"additional","affiliation":[{"name":"Altman Dermatology Associates; Arlington Heights IL U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Waterman","sequence":"additional","affiliation":[{"name":"Deaconess Clinic, Inc.; Evansville IN U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Jarratt","sequence":"additional","affiliation":[{"name":"DermResearch, Inc.; Austin TX U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the PDT Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2016,2,28]]},"reference":[{"key":"10.1111\/bjd.14345-BIB0001|bjd14345-cit-0001","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/bjd.12149","article-title":"Epidemiology of acne vulgaris","volume":"168","author":"Bhate","year":"2013","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.14345-BIB0002|bjd14345-cit-0002","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.2165\/00003495-200363150-00005","article-title":"Current concepts of the pathogenesis of acne: implications for drug treatment","volume":"63","author":"Gollnick","year":"2003","journal-title":"Drugs"},{"issue":"5 Suppl.","key":"10.1111\/bjd.14345-BIB0003|bjd14345-cit-0003","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.jaad.2009.01.019","article-title":"New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne Group","volume":"60","author":"Thiboutot","year":"2009","journal-title":"J Am Acad Dermatol"},{"issue":"Suppl. 3","key":"10.1111\/bjd.14345-BIB0004|bjd14345-cit-0004","doi-asserted-by":"crossref","first-page":"S163","DOI":"10.1542\/peds.2013-0490B","article-title":"Evidence-based recommendations for the diagnosis and treatment of pediatric acne","volume":"131","author":"Eichenfield","year":"2013","journal-title":"Pediatrics"},{"key":"10.1111\/bjd.14345-BIB0005|bjd14345-cit-0005","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.jaad.2006.08.048","article-title":"Guidelines of care for acne vulgaris management","volume":"56","author":"Strauss","year":"2007","journal-title":"J Am Acad Dermatol"},{"issue":"Suppl. 1","key":"10.1111\/bjd.14345-BIB0006|bjd14345-cit-0006","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1468-3083.2011.04374.x","article-title":"European evidence-based (S3) guidelines for the treatment of acne","volume":"26","author":"Nast","year":"2012","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1111\/bjd.14345-BIB0007|bjd14345-cit-0007","doi-asserted-by":"crossref","first-page":"S188","DOI":"10.1067\/mjd.2001.113719","article-title":"Analysis of common side-effects of isotretinoin","volume":"45","author":"McLane","year":"2001","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.14345-BIB0008|bjd14345-cit-0008","doi-asserted-by":"crossref","first-page":"c5812","DOI":"10.1136\/bmj.c5812","article-title":"Association of suicide attempts with acne and treatment with isotretinoin: retrospective Swedish cohort study","volume":"341","author":"Sundstr\u00f6m","year":"2010","journal-title":"BMJ"},{"key":"10.1111\/bjd.14345-BIB0009|bjd14345-cit-0009","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1111\/j.1365-2133.2011.10369.x","article-title":"Acne, isotretinoin and suicide attempts: a critical appraisal","volume":"164","author":"Langan","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.14345-BIB0010|bjd14345-cit-0010","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1001\/archderm.141.5.557","article-title":"Isotretinoin therapy and mood changes in adolescents with moderate to severe acne: a cohort study","volume":"141","author":"Chia","year":"2005","journal-title":"Arch Dermatol"},{"key":"10.1111\/bjd.14345-BIB0011|bjd14345-cit-0011","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.sder.2008.03.005","article-title":"Depression and suicidal behavior in acne patients treated with isotretinoin: a systematic review","volume":"26","author":"Marqueling","year":"2007","journal-title":"Semin Cutan Med Surg"},{"key":"10.1111\/bjd.14345-BIB0012|bjd14345-cit-0012","first-page":"94","article-title":"Acne vulgaris in the United States: a descriptive epidemiology","volume":"86","author":"Yentzer","year":"2010","journal-title":"Cutis"},{"key":"10.1111\/bjd.14345-BIB0013|bjd14345-cit-0013","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/j.1365-2133.2004.06110.x","article-title":"Topical aminolaevulinic acid-photodynamic therapy for the treatment of acne vulgaris: a study of clinical efficacy and mechanism of action","volume":"151","author":"Pollock","year":"2004","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.14345-BIB0014|bjd14345-cit-0014","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1046\/j.1523-1747.2000.00046.x","article-title":"Topical ALA-photodynamic therapy for the treatment of acne vulgaris","volume":"115","author":"Hongcharu","year":"2000","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.14345-BIB0015|bjd14345-cit-0015","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1111\/j.1365-2133.2006.07340.x","article-title":"Topical methyl aminolaevulinate photodynamic therapy for treatment of facial acne vulgaris: results of a randomized, controlled study","volume":"155","author":"H\u00f6rfelt","year":"2006","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.14345-BIB0016|bjd14345-cit-0016","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1111\/j.1365-2133.2005.07107.x","article-title":"Photodynamic therapy of acne vulgaris using methyl aminolaevulinate: a blinded, randomized, controlled trial","volume":"154","author":"Wiegell","year":"2006","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.14345-BIB0017|bjd14345-cit-0017","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.jaad.2005.12.033","article-title":"Photodynamic therapy of acne vulgaris using 5-aminolevulinic acid versus methyl aminolevulinate","volume":"54","author":"Wiegell","year":"2006","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.14345-BIB0018|bjd14345-cit-0018","first-page":"1347","article-title":"Photodynamic therapy with methylaminolevulinate 80 mg g\u22121 without occlusion improves acne vulgaris","volume":"9","author":"Bissonnette","year":"2010","journal-title":"J Drugs Dermatol"},{"key":"10.1111\/bjd.14345-BIB0019|bjd14345-cit-0019","unstructured":"U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) 2005 Guidance for industry. Acne vulgaris: developing drugs for treatment http:\/\/www.fda.gov\/downloads\/Drugs\/GuidanceComplianceRegulatoryInformation\/Guidances\/UCM071292.pdf"},{"key":"10.1111\/bjd.14345-BIB0020|bjd14345-cit-0020","first-page":"565","article-title":"An expert view on the treatment of acne with systemic antibiotics and\/or oral isotretinoin in the light of the new European recommendations","volume":"16","author":"Dr\u00e9no","year":"2006","journal-title":"Eur J Dermatol"},{"key":"10.1111\/bjd.14345-BIB0021|bjd14345-cit-0021","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0140-6736(11)60321-8","article-title":"Acne vulgaris","volume":"379","author":"Williams","year":"2012","journal-title":"Lancet"},{"key":"10.1111\/bjd.14345-BIB0022|bjd14345-cit-0022","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.jaad.2009.09.056","article-title":"Photodynamic therapy for acne vulgaris: a critical review from basics to clinical practice. Part 1. Acne vulgaris: when and why consider photodynamic therapy?","volume":"63","author":"Sakamoto","year":"2010","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.14345-BIB0023|bjd14345-cit-0023","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jaad.2009.09.057","article-title":"Photodynamic therapy for acne vulgaris: a critical review from basics to clinical practice. Part 2. Understanding parameters for acne treatment with photodynamic therapy","volume":"63","author":"Sakamoto","year":"2010","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.14345-BIB0024|bjd14345-cit-0024","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1346-8138.2007.00403.x-i1","article-title":"Establishment of grading criteria for acne severity","volume":"35","author":"Hayashi","year":"2008","journal-title":"J Dermatol"},{"key":"10.1111\/bjd.14345-BIB0025|bjd14345-cit-0025","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1067\/mjd.2002.120912","article-title":"Acne therapy: a methodological review","volume":"47","author":"Lehmann","year":"2002","journal-title":"J Am Acad Dermatol"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbjd.14345","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/bjd.14345\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T01:16:37Z","timestamp":1718241397000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/174\/4\/770\/6617897"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,28]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"URL":"https:\/\/doi.org\/10.1111\/bjd.14345","archive":["Portico"],"relation":{},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2,28]]}}}