{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T02:39:41Z","timestamp":1789007981859,"version":"build-2803163510"},"reference-count":114,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2016,11,30]],"date-time":"2016-11-30T00:00:00Z","timestamp":1480464000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2016,11,30]],"date-time":"2016-11-30T00:00:00Z","timestamp":1480464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Dermatol"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1111\/bjd.15105","type":"journal-article","created":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T04:22:00Z","timestamp":1480566120000},"page":"603-613","source":"Crossref","is-referenced-by-count":69,"title":["Are neutrophilic dermatoses autoinflammatory disorders?"],"prefix":"10.1093","volume":"178","author":[{"given":"T.K.","family":"Satoh","sequence":"first","affiliation":[{"name":"Department of Dermatology; University Hospital Zurich; Gloriastra\u00dfe 31 Zurich 8091 Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Mellett","sequence":"additional","affiliation":[{"name":"Department of Dermatology; University Hospital Zurich; Gloriastra\u00dfe 31 Zurich 8091 Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Contassot","sequence":"additional","affiliation":[{"name":"Department of Dermatology; University Hospital Zurich; Gloriastra\u00dfe 31 Zurich 8091 Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.E.","family":"French","sequence":"additional","affiliation":[{"name":"Department of Dermatology; University Hospital Zurich; Gloriastra\u00dfe 31 Zurich 8091 Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,11,30]]},"reference":[{"key":"10.1111\/bjd.15105-BIB0001|bjd15105-cit-0001","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/nri1785","article-title":"Neutrophils and immunity: challenges and opportunities","volume":"6","author":"Nathan","year":"2006","journal-title":"Nat Rev Immunol"},{"key":"10.1111\/bjd.15105-BIB0002|bjd15105-cit-0002","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1182\/blood-2013-07-516484","article-title":"Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap-mediated sterile inflammation","volume":"123","author":"Rossaint","year":"2014","journal-title":"Blood"},{"key":"10.1111\/bjd.15105-BIB0003|bjd15105-cit-0003","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.4049\/jimmunol.180.3.1895","article-title":"Histone deimination as a response to inflammatory stimuli in neutrophils","volume":"180","author":"Neeli","year":"2008","journal-title":"J Immunol"},{"key":"10.1111\/bjd.15105-BIB0004|bjd15105-cit-0004","doi-asserted-by":"crossref","first-page":"376","DOI":"10.3389\/fimmu.2012.00376","article-title":"Bonding the foe - NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals","volume":"3","author":"Schorn","year":"2012","journal-title":"Front Immunol"},{"key":"10.1111\/bjd.15105-BIB0005|bjd15105-cit-0005","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1136\/annrheumdis-2014-205958","article-title":"Neutrophil extracellular traps regulate IL-1\u03b2-mediated inflammation in familial Mediterranean fever","volume":"75","author":"Apostolidou","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"10.1111\/bjd.15105-BIB0006|bjd15105-cit-0006","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1159\/000247696","article-title":"Cutaneous manifestations of neutrophilic disease. A study of seven cases","volume":"183","author":"Vignon-Pennamen","year":"1991","journal-title":"Dermatologica"},{"key":"10.1111\/bjd.15105-BIB0007|bjd15105-cit-0007","doi-asserted-by":"crossref","first-page":"e297","DOI":"10.1371\/journal.pmed.0030297","article-title":"A proposed classification of the immunological diseases","volume":"3","author":"McGonagle","year":"2006","journal-title":"PLoS Med"},{"key":"10.1111\/bjd.15105-BIB0008|bjd15105-cit-0008","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0092-8674(00)80721-7","article-title":"Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes","volume":"97","author":"McDermott","year":"1999","journal-title":"Cell"},{"key":"10.1111\/bjd.15105-BIB0009|bjd15105-cit-0009","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s12016-012-8351-x","article-title":"Autoinflammatory skin disorders in inflammatory bowel diseases, pyoderma gangrenosum and Sweet's syndrome: a comprehensive review and disease classification criteria","volume":"45","author":"Marzano","year":"2013","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1111\/bjd.15105-BIB0010|bjd15105-cit-0010","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1126\/science.1092385","article-title":"Neutrophil extracellular traps kill bacteria","volume":"303","author":"Brinkmann","year":"2004","journal-title":"Science"},{"key":"10.1111\/bjd.15105-BIB0011|bjd15105-cit-0011","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.4049\/jimmunol.1201719","article-title":"Neutrophil extracellular traps: double-edged swords of innate immunity","volume":"189","author":"Kaplan","year":"2012","journal-title":"J Immunol"},{"key":"10.1111\/bjd.15105-BIB0012|bjd15105-cit-0012","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0065-2776(08)60791-9","article-title":"Neutrophil-derived proteins: selling cytokines by the pound","volume":"73","author":"Cassatella","year":"1999","journal-title":"Adv Immunol"},{"key":"10.1111\/bjd.15105-BIB0013|bjd15105-cit-0013","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1034\/j.1600-065X.2000.17706.x","article-title":"The neutrophil as a cellular source of chemokines","volume":"177","author":"Scapini","year":"2000","journal-title":"Immunol Rev"},{"key":"10.1111\/bjd.15105-BIB0014|bjd15105-cit-0014","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.it.2011.06.008","article-title":"Neutrophils cascading their way to inflammation","volume":"32","author":"Sadik","year":"2011","journal-title":"Trends Immunol"},{"key":"10.1111\/bjd.15105-BIB0015|bjd15105-cit-0015","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1182\/blood-2014-03-453217","article-title":"Social networking of human neutrophils within the immune system","volume":"124","author":"Scapini","year":"2014","journal-title":"Blood"},{"key":"10.1111\/bjd.15105-BIB0016|bjd15105-cit-0016","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1038\/nature01320","article-title":"Points of control in inflammation","volume":"420","author":"Nathan","year":"2002","journal-title":"Nature"},{"key":"10.1111\/bjd.15105-BIB0017|bjd15105-cit-0017","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1146\/annurev-pathol-012414-040431","article-title":"The inflammasomes and autoinflammatory syndromes","volume":"10","author":"Broderick","year":"2015","journal-title":"Annu Rev Pathol"},{"key":"10.1111\/bjd.15105-BIB0018|bjd15105-cit-0018","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/ng756","article-title":"Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome","volume":"29","author":"Hoffman","year":"2001","journal-title":"Nat Genet"},{"key":"10.1111\/bjd.15105-BIB0019|bjd15105-cit-0019","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S1097-2765(02)00599-3","article-title":"The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-\u03b2","volume":"10","author":"Martinon","year":"2002","journal-title":"Mol Cell"},{"key":"10.1111\/bjd.15105-BIB0020|bjd15105-cit-0020","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.4049\/jimmunol.1300387","article-title":"Excess IL-1 signaling enhances the development of Th17 cells by downregulating TGF-\u03b2-induced Foxp3 expression","volume":"192","author":"Ikeda","year":"2014","journal-title":"J Immunol"},{"key":"10.1111\/bjd.15105-BIB0021|bjd15105-cit-0021","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1182\/blood-2009-04-216085","article-title":"Evidence for a cross-talk between human neutrophils and Th17 cells","volume":"115","author":"Pelletier","year":"2010","journal-title":"Blood"},{"key":"10.1111\/bjd.15105-BIB0022|bjd15105-cit-0022","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1002\/eji.200940025","article-title":"Regulation of the autophagic machinery in human neutrophils","volume":"40","author":"Mitroulis","year":"2010","journal-title":"Eur J Immunol"},{"key":"10.1111\/bjd.15105-BIB0023|bjd15105-cit-0023","doi-asserted-by":"crossref","first-page":"957","DOI":"10.4049\/jimmunol.161.2.957","article-title":"The IL-1 \u03b2-converting enzyme (caspase-1) inhibits apoptosis of inflammatory neutrophils through activation of IL-1 \u03b2","volume":"161","author":"Watson","year":"1998","journal-title":"J Immunol"},{"key":"10.1111\/bjd.15105-BIB0024|bjd15105-cit-0024","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1002\/eji.201141921","article-title":"The NLRP3\/ASC\/caspase-1 axis regulates IL-1\u03b2 processing in neutrophils","volume":"42","author":"Mankan","year":"2012","journal-title":"Eur J Immunol"},{"key":"10.1111\/bjd.15105-BIB0025|bjd15105-cit-0025","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.celrep.2014.06.028","article-title":"The neutrophil NLRC4 inflammasome selectively promotes IL-1\u03b2 maturation without pyroptosis during acute Salmonella challenge","volume":"8","author":"Chen","year":"2014","journal-title":"Cell Rep"},{"key":"10.1111\/bjd.15105-BIB0026|bjd15105-cit-0026","doi-asserted-by":"crossref","first-page":"6318","DOI":"10.1016\/S0021-9258(19)39328-7","article-title":"Processing of precursor interleukin 1\u03b2 and inflammatory disease","volume":"265","author":"Hazuda","year":"1990","journal-title":"J Biol Chem"},{"key":"10.1111\/bjd.15105-BIB0027|bjd15105-cit-0027","doi-asserted-by":"crossref","first-page":"3642","DOI":"10.1002\/art.24959","article-title":"Caspase 1-independent activation of interleukin-1\u03b2 in neutrophil-predominant inflammation","volume":"60","author":"Guma","year":"2009","journal-title":"Arthritis Rheum"},{"key":"10.1111\/bjd.15105-BIB0028|bjd15105-cit-0028","doi-asserted-by":"crossref","first-page":"3651","DOI":"10.1002\/art.25006","article-title":"Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1\u03b2","volume":"60","author":"Joosten","year":"2009","journal-title":"Arthritis Rheum"},{"key":"10.1111\/bjd.15105-BIB0029|bjd15105-cit-0029","doi-asserted-by":"crossref","first-page":"6053","DOI":"10.4049\/jimmunol.1301481","article-title":"IL-36 promotes myeloid cell infiltration, activation, and inflammatory activity in skin","volume":"192","author":"Foster","year":"2014","journal-title":"J Immunol"},{"key":"10.1111\/bjd.15105-BIB0030|bjd15105-cit-0030","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1006\/bbrc.1999.1440","article-title":"IL1HY1: a novel interleukin-1 receptor antagonist gene","volume":"263","author":"Mulero","year":"1999","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1111\/bjd.15105-BIB0031|bjd15105-cit-0031","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.4049\/jimmunol.1003162","article-title":"IL-1F5, -F6, -F8, and -F9: a novel IL-1 family signalling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expression","volume":"186","author":"Johnston","year":"2011","journal-title":"J Immunol"},{"key":"10.1111\/bjd.15105-BIB0032|bjd15105-cit-0032","doi-asserted-by":"crossref","first-page":"e101954","DOI":"10.1371\/journal.pone.0101954","article-title":"Blockade of IL-36 receptor signaling does not prevent from TNF-induced arthritis","volume":"9","author":"Derer","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1111\/bjd.15105-BIB0033|bjd15105-cit-0033","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.celrep.2015.12.072","article-title":"Neutrophil-derived proteases escalate inflammation through activation of IL-36 family cytokines","volume":"14","author":"Henry","year":"2016","journal-title":"Cell Rep"},{"key":"10.1111\/bjd.15105-BIB0034|bjd15105-cit-0034","doi-asserted-by":"crossref","first-page":"24880","DOI":"10.1038\/srep24880","article-title":"Neutrophil elastase-mediated proteolysis activates the anti-inflammatory cytokine IL-36 receptor antagonist","volume":"6","author":"Macleod","year":"2016","journal-title":"Sci Rep"},{"key":"10.1111\/bjd.15105-BIB0035|bjd15105-cit-0035","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1111\/odi.12448","article-title":"Genetically defined autoinflammatory diseases","volume":"22","author":"Almeida de Jesus","year":"2016","journal-title":"Oral Dis"},{"key":"10.1111\/bjd.15105-BIB0036|bjd15105-cit-0036","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1002\/art.22841","article-title":"Mutations in cryopyrin: bypassing roadblocks in the caspase 1 inflammasome for interleukin-1\u03b2 secretion and disease activity","volume":"56","author":"Dinarello","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1111\/bjd.15105-BIB0037|bjd15105-cit-0037","doi-asserted-by":"crossref","first-page":"243","DOI":"10.2217\/imt.14.106","article-title":"The inflammasome and IL-1\u03b2: implications for the treatment of inflammatory diseases","volume":"7","author":"Satoh","year":"2015","journal-title":"Immunotherapy"},{"key":"10.1111\/bjd.15105-BIB0038|bjd15105-cit-0038","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.jaad.2006.07.016","article-title":"From acute febrile neutrophilic dermatosis to neutrophilic disease: forty years of clinical research","volume":"55","author":"Wallach","year":"2006","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.15105-BIB0039|bjd15105-cit-0039","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1146\/annurev.immunol.25.022106.141627","article-title":"Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease","volume":"27","author":"Masters","year":"2009","journal-title":"Annu Rev Immunol"},{"key":"10.1111\/bjd.15105-BIB0040|bjd15105-cit-0040","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/ncprheum0874","article-title":"Cryopyrinopathies: update on pathogenesis and treatment","volume":"4","author":"Neven","year":"2008","journal-title":"Nat Clin Pract Rheumatol"},{"key":"10.1111\/bjd.15105-BIB0041|bjd15105-cit-0041","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.1002\/art.30512","article-title":"High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome: results of an International Multicenter Collaborative Study","volume":"63","author":"Tanaka","year":"2011","journal-title":"Arthritis Rheum"},{"key":"10.1111\/bjd.15105-BIB0042|bjd15105-cit-0042","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1056\/NEJMoa0807865","article-title":"An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist","volume":"360","author":"Aksentijevich","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1111\/bjd.15105-BIB0043|bjd15105-cit-0043","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1056\/NEJMoa0809568","article-title":"An autoinflammatory disease due to homozygous deletion of the IL1RN locus","volume":"360","author":"Reddy","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1111\/bjd.15105-BIB0044|bjd15105-cit-0044","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.semarthrit.2007.04.001","article-title":"Schnitzler syndrome: beyond the case reports: review and follow-up of 94 patients with an emphasis on prognosis and treatment","volume":"37","author":"Koning","year":"2007","journal-title":"Semin Arthritis Rheum"},{"key":"10.1111\/bjd.15105-BIB0045|bjd15105-cit-0045","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.jaci.2014.07.050","article-title":"Myeloid lineage-restricted somatic mosaicism of NLRP3 mutations in patients with variant Schnitzler syndrome","volume":"135","author":"Koning","year":"2015","journal-title":"J Allergy Clin Immunol"},{"key":"10.1111\/bjd.15105-BIB0046|bjd15105-cit-0046","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jbspin.2007.07.014","article-title":"Schnitzler syndrome","volume":"75","author":"Soubrier","year":"2008","journal-title":"Joint Bone Spine"},{"key":"10.1111\/bjd.15105-BIB0047|bjd15105-cit-0047","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1111\/all.12129","article-title":"Schnitzler's syndrome: diagnosis, treatment, and follow-up","volume":"68","author":"Simon","year":"2013","journal-title":"Allergy"},{"key":"10.1111\/bjd.15105-BIB0048|bjd15105-cit-0048","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/j.autrev.2014.08.031","article-title":"Long-term effectiveness and safety of interleukin-1 receptor antagonist (anakinra) in Schnitzler's syndrome: a French multicenter study","volume":"13","author":"Neel","year":"2014","journal-title":"Autoimmun Rev"},{"key":"10.1111\/bjd.15105-BIB0049|bjd15105-cit-0049","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1056\/NEJMoa1013068","article-title":"Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis","volume":"365","author":"Marrakchi","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1111\/bjd.15105-BIB0050|bjd15105-cit-0050","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.ajhg.2011.07.022","article-title":"Mutations in IL36RN\/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis","volume":"89","author":"Onoufriadis","year":"2011","journal-title":"Am J Hum Genet"},{"key":"10.1111\/bjd.15105-BIB0051|bjd15105-cit-0051","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.ajhg.2012.03.013","article-title":"Rare and common variants in CARD14, encoding an epidermal regulator of NF-\u03baB, in psoriasis","volume":"90","author":"Jordan","year":"2012","journal-title":"Am J Hum Genet"},{"key":"10.1111\/bjd.15105-BIB0052|bjd15105-cit-0052","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.ajhg.2012.03.012","article-title":"PSORS2 is due to mutations in CARD14","volume":"90","author":"Jordan","year":"2012","journal-title":"Am J Hum Genet"},{"key":"10.1111\/bjd.15105-BIB0053|bjd15105-cit-0053","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.ajhg.2012.05.010","article-title":"Familial pityriasis rubra pilaris is caused by mutations in CARD14","volume":"91","author":"Fuchs-Telem","year":"2012","journal-title":"Am J Hum Genet"},{"key":"10.1111\/bjd.15105-BIB0054|bjd15105-cit-0054","doi-asserted-by":"crossref","first-page":"11877","DOI":"10.1074\/jbc.M010512200","article-title":"CARD11 and CARD14 are novel caspase recruitment domain (CARD)\/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-\u03baB","volume":"276","author":"Bertin","year":"2001","journal-title":"J Biol Chem"},{"issue":"Suppl. S10","key":"10.1111\/bjd.15105-BIB0055|bjd15105-cit-0055","first-page":"S769","article-title":"Immune activating effects of co-stimulation of TLR agonists and cytokines on primary and immortalized keratinocytes from a patient with a CARD14 mediated pustular psoriasis (CAMPS) and healthy controls","volume":"64","author":"Chen","year":"2012","journal-title":"Arthritis Rheum"},{"issue":"Suppl. S10","key":"10.1111\/bjd.15105-BIB0056|bjd15105-cit-0056","first-page":"310","article-title":"Pathogenesis study of infantile-onset, severe pustular psoriasis reveals a de novo mutation in CARD14 causing psoriasis which responds clinically to IL-12\/23 blocking treatment with ustekinumab","volume":"63","author":"Habal","year":"2011","journal-title":"Arthritis Rheum"},{"key":"10.1111\/bjd.15105-BIB0057|bjd15105-cit-0057","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1093\/hmg\/11.8.961","article-title":"Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder","volume":"11","author":"Wise","year":"2002","journal-title":"Hum Mol Genet"},{"key":"10.1111\/bjd.15105-BIB0058|bjd15105-cit-0058","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1001\/jamadermatol.2013.2907","article-title":"Pyogenic arthritis, pyoderma gangrenosum, acne, and hidradenitis suppurativa (PAPASH): a new autoinflammatory syndrome associated with a novel mutation of the PSTPIP1 gene","volume":"149","author":"Marzano","year":"2013","journal-title":"JAMA Dermatol"},{"key":"10.1111\/bjd.15105-BIB0059|bjd15105-cit-0059","doi-asserted-by":"crossref","first-page":"13501","DOI":"10.1073\/pnas.2135380100","article-title":"Pyrin binds the PSTPIP1\/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway","volume":"100","author":"Shoham","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1111\/bjd.15105-BIB0060|bjd15105-cit-0060","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1111\/j.1365-2230.2011.04137.x","article-title":"Mutations in the PSTPIP1 gene and aberrant splicing variants in patients with pyoderma gangrenosum","volume":"36","author":"Nesterovitch","year":"2011","journal-title":"Clin Exp Dermatol"},{"key":"10.1111\/bjd.15105-BIB0061|bjd15105-cit-0061","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1002\/art.34332","article-title":"Brief report: genotype, phenotype, and clinical course in five patients with PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne)","volume":"64","author":"Demidowich","year":"2012","journal-title":"Arthritis Rheum"},{"key":"10.1111\/bjd.15105-BIB0062|bjd15105-cit-0062","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.clim.2013.03.016","article-title":"Monogenic autoinflammatory diseases: concept and clinical manifestations","volume":"147","author":"Almeida de Jesus","year":"2013","journal-title":"Clin Immunol"},{"key":"10.1111\/bjd.15105-BIB0063|bjd15105-cit-0063","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.jaad.2010.12.025","article-title":"Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH) - a new autoinflammatory syndrome distinct from PAPA syndrome","volume":"66","author":"Braun-Falco","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.15105-BIB0064|bjd15105-cit-0064","doi-asserted-by":"crossref","first-page":"e187","DOI":"10.1097\/MD.0000000000000187","article-title":"Association of pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH) shares genetic and cytokine profiles with other autoinflammatory diseases","volume":"93","author":"Marzano","year":"2014","journal-title":"Medicine"},{"key":"10.1111\/bjd.15105-BIB0065|bjd15105-cit-0065","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1111\/bjd.14691","article-title":"Pyoderma gangrenosum and its syndromic forms: evidence for a link with autoinflammation","volume":"175","author":"Marzano","year":"2016","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15105-BIB0066|bjd15105-cit-0066","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1111\/bjd.13668","article-title":"First nicastrin mutation in PASH syndrome","volume":"173","author":"Duchatelet","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15105-BIB0067|bjd15105-cit-0067","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/jid.2012.372","article-title":"\u03b3-Secretase mutations in hidradenitis suppurativa: new insights into disease pathogenesis","volume":"133","author":"Pink","year":"2013","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.15105-BIB0068|bjd15105-cit-0068","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1126\/science.1196284","article-title":"Gamma-secretase gene mutations in familial acne inversa","volume":"330","author":"Wang","year":"2010","journal-title":"Science"},{"key":"10.1111\/bjd.15105-BIB0069|bjd15105-cit-0069","volume-title":"Fitzpatrick's Dermatology in General Medicine","author":"Goldsmith","year":"2012","edition":"8"},{"key":"10.1111\/bjd.15105-BIB0070|bjd15105-cit-0070","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1111\/bjd.13493","article-title":"The genetics of pyoderma gangrenosum and implications for treatment: a systematic review","volume":"172","author":"DeFilippis","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15105-BIB0071|bjd15105-cit-0071","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1111\/bjd.14037","article-title":"Canakinumab in adults with steroid-refractory pyoderma gangrenosum","volume":"173","author":"Kolios","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15105-BIB0072|bjd15105-cit-0072","first-page":"167","article-title":"Diagnostic criteria for Sweet's syndrome","volume":"37","author":"Su","year":"1986","journal-title":"Cutis"},{"key":"10.1111\/bjd.15105-BIB0073|bjd15105-cit-0073","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1111\/j.1610-0387.2011.07636.x","article-title":"Typically atypical: histiocytoid Sweet syndrome, associated with malignancy","volume":"9","author":"Hunermund","year":"2011","journal-title":"J Deutsch Dermatol Ges"},{"key":"10.1111\/bjd.15105-BIB0074|bjd15105-cit-0074","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1016\/j.ajpath.2010.12.053","article-title":"Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans","volume":"178","author":"Nesterovitch","year":"2011","journal-title":"Am J Pathol"},{"key":"10.1111\/bjd.15105-BIB0075|bjd15105-cit-0075","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1016\/j.ajpath.2010.12.035","article-title":"Alteration in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6\/SHP1) may contribute to neutrophilic dermatoses","volume":"178","author":"Nesterovitch","year":"2011","journal-title":"Am J Pathol"},{"key":"10.1111\/bjd.15105-BIB0076|bjd15105-cit-0076","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/cei.12394","article-title":"Expression of cytokines, chemokines and other effector molecules in two prototypic autoinflammatory skin diseases, pyoderma gangrenosum and Sweet's syndrome","volume":"178","author":"Marzano","year":"2014","journal-title":"Clin Exp Immunol"},{"key":"10.1111\/bjd.15105-BIB0077|bjd15105-cit-0077","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1136\/ard.2006.068254","article-title":"Efficacy of anakinra, an IL1 receptor antagonist, in refractory Sweet syndrome","volume":"67","author":"Delluc","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"10.1111\/bjd.15105-BIB0078|bjd15105-cit-0078","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1159\/000326112","article-title":"Efficacy of anti-interleukin-1 receptor antagonist anakinra (Kineret) in a case of refractory Sweet's syndrome","volume":"222","author":"Kluger","year":"2011","journal-title":"Dermatology"},{"key":"10.1111\/bjd.15105-BIB0079|bjd15105-cit-0079","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1159\/000371879","article-title":"Severe Sweet's syndrome with elevated cutaneous interleukin-1\u03b2 after azathioprine exposure: case report and review of the literature","volume":"230","author":"Imhof","year":"2015","journal-title":"Dermatology"},{"key":"10.1111\/bjd.15105-BIB0080|bjd15105-cit-0080","first-page":"291","article-title":"Behcet's disease: autoimmune or autoinflammatory?","volume":"8","author":"Hedayatfar","year":"2013","journal-title":"J Ophthalmic Vis Res"},{"key":"10.1111\/bjd.15105-BIB0081|bjd15105-cit-0081","doi-asserted-by":"crossref","first-page":"261","DOI":"10.2174\/09298673113206660303","article-title":"An update on autoinflammatory diseases","volume":"21","author":"Ciccarelli","year":"2014","journal-title":"Curr Med Chem"},{"key":"10.1111\/bjd.15105-BIB0082|bjd15105-cit-0082","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/ncprheum0436","article-title":"Behcet's syndrome: disease manifestations, management, and advances in treatment","volume":"3","author":"Yazici","year":"2007","journal-title":"Nat Clin Prac Rheumatol"},{"key":"10.1111\/bjd.15105-BIB0083|bjd15105-cit-0083","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/ng.625","article-title":"Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behcet's disease","volume":"42","author":"Remmers","year":"2010","journal-title":"Nat Genet"},{"key":"10.1111\/bjd.15105-BIB0084|bjd15105-cit-0084","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/ng.624","article-title":"Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behcet's disease susceptibility loci","volume":"42","author":"Mizuki","year":"2010","journal-title":"Nat Genet"},{"key":"10.1111\/bjd.15105-BIB0085|bjd15105-cit-0085","doi-asserted-by":"crossref","first-page":"2761","DOI":"10.1002\/art.34437","article-title":"Association study of IL10 and IL23R-IL12RB2 in Iranian patients with Behcet's disease","volume":"64","author":"Xavier","year":"2012","journal-title":"Arthritis Rheum"},{"key":"10.1111\/bjd.15105-BIB0086|bjd15105-cit-0086","doi-asserted-by":"crossref","first-page":"342","DOI":"10.3389\/fimmu.2013.00342","article-title":"Association analysis of IL10, TNF-\u03b1, and IL23R-IL12RB2 SNPs with Behcet's disease risk in Western Algeria","volume":"4","author":"Khaib Dit Naib","year":"2013","journal-title":"Front Immunol"},{"key":"10.1111\/bjd.15105-BIB0087|bjd15105-cit-0087","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/ng.2520","article-title":"Genome-wide association analysis identifies new susceptibility loci for Behcet's disease and epistasis between HLA-B*51 and ERAP1","volume":"45","author":"Kirino","year":"2013","journal-title":"Nat Genet"},{"key":"10.1111\/bjd.15105-BIB0088|bjd15105-cit-0088","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1136\/annrheumdis-2011-200288","article-title":"Genome-wide association study identifies GIMAP as a novel susceptibility locus for Beh\u00e7et's disease","volume":"72","author":"Lee","year":"2013","journal-title":"Ann Rheum Dis"},{"key":"10.1111\/bjd.15105-BIB0089|bjd15105-cit-0089","doi-asserted-by":"crossref","first-page":"e0119085","DOI":"10.1371\/journal.pone.0119085","article-title":"Genome-wide association study in an admixed case series reveals IL12A as a new candidate in Behcet disease","volume":"10","author":"Kappen","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1111\/bjd.15105-BIB0090|bjd15105-cit-0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00296-003-0400-6","article-title":"Cytokine inhibitors: soluble tumor necrosis factor receptor 1 and interleukin-1 receptor antagonist in Behcet's disease","volume":"25","author":"D\u00fczgun","year":"2005","journal-title":"Rheumatol Int"},{"key":"10.1111\/bjd.15105-BIB0091|bjd15105-cit-0091","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1007\/s10067-015-3004-0","article-title":"Efficacy and safety profile of anti-interleukin-1 treatment in Beh\u00e7et's disease: a multicenter retrospective study","volume":"35","author":"Emmi","year":"2016","journal-title":"Clin Rheumatol"},{"key":"10.1111\/bjd.15105-BIB0092|bjd15105-cit-0092","doi-asserted-by":"crossref","first-page":"284","DOI":"10.7326\/0003-4819-149-4-200808190-00018","article-title":"Resistant Beh\u00e7et disease responsive to anakinra","volume":"149","author":"Botsios","year":"2008","journal-title":"Ann Intern Med"},{"key":"10.1111\/bjd.15105-BIB0093|bjd15105-cit-0093","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1136\/annrheumdis-2011-155143","article-title":"Interleukin-1\u03b2-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Beh\u00e7et's disease: an open-label pilot study","volume":"71","author":"Gul","year":"2012","journal-title":"Ann Rheum Dis"},{"key":"10.1111\/bjd.15105-BIB0094|bjd15105-cit-0094","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1038\/jid.2012.162","article-title":"Mutations in the \u03b3-secretase genes NCSTN, PSENEN, and PSEN1 underlie rare forms of hidradenitis suppurativa (acne inversa)","volume":"132","author":"Pink","year":"2012","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.15105-BIB0095|bjd15105-cit-0095","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1038\/jid.2011.42","article-title":"PSENEN and NCSTN mutations in familial hidradenitis suppurativa (acne inversa)","volume":"131","author":"Pink","year":"2011","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.15105-BIB0096|bjd15105-cit-0096","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/exd.12098","article-title":"Impaired Notch-MKP-1 signalling in hidradenitis suppurativa: an approach to pathogenesis by evidence from translational biology","volume":"22","author":"Melnik","year":"2013","journal-title":"Exp Dermatol"},{"key":"10.1111\/bjd.15105-BIB0097|bjd15105-cit-0097","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1111\/j.1365-2133.2011.10254.x","article-title":"Elevated levels of tumour necrosis factor (TNF)-\u03b1, interleukin (IL)-1\u03b2 and IL-10 in hidradenitis suppurativa skin: a rationale for targeting TNF-\u03b1 and IL-1\u03b2","volume":"164","author":"Zee","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15105-BIB0098|bjd15105-cit-0098","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.jaad.2010.07.010","article-title":"Expression of the IL-23\/Th17 pathway in lesions of hidradenitis suppurativa","volume":"65","author":"Schlapbach","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.15105-BIB0099|bjd15105-cit-0099","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1001\/jamadermatol.2013.5377","article-title":"Successful treatment of severe hidradenitis suppurativa with anakinra","volume":"149","author":"Zarchi","year":"2013","journal-title":"JAMA Dermatol"},{"key":"10.1111\/bjd.15105-BIB0100|bjd15105-cit-0100","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1111\/bjd.14338","article-title":"Ustekinumab in hidradenitis suppurativa: clinical results and a search for potential biomarkers in serum","volume":"174","author":"Blok","year":"2016","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15105-BIB0101|bjd15105-cit-0101","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1177\/096120339700600607","article-title":"A peculiar form of amicrobial pustulosis of the folds associated with systemic lupus erythematosus and other auto-immune diseases","volume":"6","author":"Lagrange","year":"1997","journal-title":"Lupus"},{"key":"10.1111\/bjd.15105-BIB0102|bjd15105-cit-0102","doi-asserted-by":"crossref","first-page":"e2301","DOI":"10.1097\/MD.0000000000002301","article-title":"Cytokine and chemokine profile in amicrobial pustulosis of the folds: evidence for autoinflammation","volume":"94","author":"Marzano","year":"2015","journal-title":"Medicine"},{"key":"10.1111\/bjd.15105-BIB0103|bjd15105-cit-0103","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1016\/j.jaad.2013.12.041","article-title":"Expression of interleukin-1\u03b1 in amicrobial pustulosis of the skin folds with complete response to anakinra","volume":"71","author":"Amazan","year":"2014","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.15105-BIB0104|bjd15105-cit-0104","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1038\/ni1010-883","article-title":"Accessory to inflammation","volume":"11","author":"Sims","year":"2010","journal-title":"Nat Immunol"},{"key":"10.1111\/bjd.15105-BIB0105|bjd15105-cit-0105","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/0190-9622(91)70290-I","article-title":"Role of tumour necrosis factor-\u03b1 in Sneddon-Wilkinson subcorneal pustular dermatosis. A model of neutrophil priming in vivo","volume":"25","author":"Grob","year":"1991","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.15105-BIB0106|bjd15105-cit-0106","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1001\/archderm.137.12.1571","article-title":"Infliximab (anti-tumor necrosis factor \u03b1 antibody): a novel, highly effective treatment of recalcitrant subcorneal pustular dermatosis (Sneddon-Wilkinson disease)","volume":"137","author":"Voigtlander","year":"2001","journal-title":"Arch Dermatol"},{"key":"10.1111\/bjd.15105-BIB0107|bjd15105-cit-0107","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1046\/j.1365-2230.1999.00534.x","article-title":"Intercellular IgA dermatosis (IgA pemphigus) - two cases illustrating the clinical heterogeneity of this disorder","volume":"24","author":"Harman","year":"1999","journal-title":"Clin Exp Dermatol"},{"key":"10.1111\/bjd.15105-BIB0108|bjd15105-cit-0108","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1111\/bjd.13012","article-title":"Partial clinical response to anakinra in severe palmoplantar pustular psoriasis","volume":"171","author":"Tauber","year":"2014","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15105-BIB0109|bjd15105-cit-0109","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/ced.12759","article-title":"Palmoplantar pustular psoriasis unresponsive to the interleukin-1\u03b2 antagonist canakinumab","volume":"41","author":"Mansouri","year":"2016","journal-title":"Clin Exp Dermatol"},{"key":"10.1111\/bjd.15105-BIB0110|bjd15105-cit-0110","first-page":"871019","article-title":"New evidence-based treatment approach in Beh\u00e7et's disease","volume":"2012","author":"Alpsoy","year":"2012","journal-title":"Patholog Res Int"},{"key":"10.1111\/bjd.15105-BIB0111|bjd15105-cit-0111","doi-asserted-by":"crossref","first-page":"199","DOI":"10.2174\/1871528113666140520100402","article-title":"Biological treatments for SAPHO syndrome: an update","volume":"13","author":"Firinu","year":"2014","journal-title":"Inflamm Allergy Drug Targets"},{"key":"10.1111\/bjd.15105-BIB0112|bjd15105-cit-0112","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1345\/aph.1H563","article-title":"Drug-induced Sweet's syndrome","volume":"41","author":"Thompson","year":"2007","journal-title":"Ann Pharmacother"},{"key":"10.1111\/bjd.15105-BIB0113|bjd15105-cit-0113","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1046\/j.1365-2133.2000.03427.x","article-title":"Neutrophilic eccrine hidradenitis secondary to infection with Serratia marcescens","volume":"142","author":"Combemale","year":"2000","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15105-BIB0114|bjd15105-cit-0114","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0889-857X(21)01060-7","article-title":"Cutaneous vasculitis","volume":"16","author":"Gibson","year":"1990","journal-title":"Rheum Dis Clin North Am"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbjd.15105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbjd.15105","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/bjd.15105\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T04:05:06Z","timestamp":1692590706000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/178\/3\/603\/6687354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,30]]},"references-count":114,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"URL":"https:\/\/doi.org\/10.1111\/bjd.15105","archive":["Portico"],"relation":{},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11,30]]}}}