{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T16:38:18Z","timestamp":1789749498235,"version":"4.0.1"},"reference-count":174,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2017,6,14]],"date-time":"2017-06-14T00:00:00Z","timestamp":1497398400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,6,14]],"date-time":"2017-06-14T00:00:00Z","timestamp":1497398400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Dermatol"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1111\/bjd.15193","type":"journal-article","created":{"date-parts":[[2016,11,19]],"date-time":"2016-11-19T09:52:40Z","timestamp":1479549160000},"page":"72-83","source":"Crossref","is-referenced-by-count":61,"title":["Drug-induced pyoderma gangrenosum: a model to understand the pathogenesis of pyoderma gangrenosum"],"prefix":"10.1093","volume":"177","author":[{"given":"B.C.","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Medicine; Drexel University College of Medicine\/Hahnemann University Hospital; Philadelphia PA U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.D.","family":"Patel","sequence":"additional","affiliation":[{"name":"Virginia Commonwealth University School of Medicine; Richmond VA U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.G.","family":"Ortega-Loayza","sequence":"additional","affiliation":[{"name":"Center for Wound and Healing; Department of Dermatology; Oregon Health & Science University; 3303 SW Bond Avenue, CHD 16D Portland OR 97034 U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,6,14]]},"reference":[{"key":"10.1111\/bjd.15193-BIB0001|bjd15193-cit-0001","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1034\/j.1600-0560.2003.00024.x","article-title":"Pyoderma gangrenosum: a review","volume":"30","author":"Crowson","year":"2003","journal-title":"J Cutan Pathol"},{"key":"10.1111\/bjd.15193-BIB0002|bjd15193-cit-0002","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2165\/11595240-000000000-00000","article-title":"Etiology and management of pyoderma gangrenosum: a comprehensive review","volume":"13","author":"Ahronowitz","year":"2012","journal-title":"Am J Clin Dermatol"},{"key":"10.1111\/bjd.15193-BIB0003|bjd15193-cit-0003","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.jaad.2015.06.021","article-title":"Pathophysiology of pyoderma gangrenosum (PG): an updated review","volume":"73","author":"Braswell","year":"2015","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.15193-BIB0004|bjd15193-cit-0004","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1001\/archderm.1983.01650340018012","article-title":"Pyogenic granuloma-like acne lesions during isotretinoin therapy","volume":"119","author":"Exner","year":"1983","journal-title":"Arch Dermatol"},{"key":"10.1111\/bjd.15193-BIB0005|bjd15193-cit-0005","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1111\/j.1365-4632.2008.03662.x","article-title":"Pyoderma gangrenosum following isotretinoin therapy for acne nodulocystic","volume":"47","author":"Tinoco","year":"2008","journal-title":"Int J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0006|bjd15193-cit-0006","doi-asserted-by":"crossref","first-page":"S107","DOI":"10.1016\/j.jaad.2005.09.017","article-title":"Pyoderma gangrenosum associated with isotretinoin therapy","volume":"55","author":"Freiman","year":"2006","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.15193-BIB0007|bjd15193-cit-0007","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1111\/j.1365-2133.1997.tb02168.x","article-title":"Pyoderma gangrenosum following treatment with isotretinoin","volume":"136","author":"Gangaram","year":"1997","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0008|bjd15193-cit-0008","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1111\/j.1365-2133.1990.tb07291.x","article-title":"Development of folliculitis and pyoderma gangrenosum in association with abdominal pain in a patient following treatment with isotretinoin","volume":"122","author":"Hughes","year":"1990","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0009|bjd15193-cit-0009","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jdcr.2016.01.003","article-title":"Pyoderma gangrenosum associated with alitretinoin therapy","volume":"2","author":"Levy","year":"2016","journal-title":"JAAD Case Reports"},{"key":"10.1111\/bjd.15193-BIB0010|bjd15193-cit-0010","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1111\/j.1365-4632.2006.02749.x","article-title":"Adverse reactions to gefitinib (Iressa): revealing sycosis- and pyoderma gangrenosum-like lesions","volume":"45","author":"Sagara","year":"2006","journal-title":"Int J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0011|bjd15193-cit-0011","doi-asserted-by":"crossref","first-page":"244","DOI":"10.4103\/0022-3859.118059","article-title":"Imatinib induced pyoderma gangrenosum","volume":"59","author":"Sharma","year":"2013","journal-title":"J Postgrad Med"},{"key":"10.1111\/bjd.15193-BIB0012|bjd15193-cit-0012","doi-asserted-by":"crossref","first-page":"e266","DOI":"10.1200\/JCO.2010.32.6165","article-title":"Pyoderma gangrenosum with the use of sunitinib","volume":"29","author":"Nadauld","year":"2011","journal-title":"J Clin Oncol"},{"key":"10.1111\/bjd.15193-BIB0013|bjd15193-cit-0013","first-page":"34","article-title":"A second case of sunitinib-associated pyoderma gangrenosum","volume":"3","author":"Dean","year":"2010","journal-title":"J Clin Aesthet Dermatol"},{"key":"10.1111\/bjd.15193-BIB0014|bjd15193-cit-0014","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/j.1365-4632.2011.04952.x","article-title":"A case of pyoderma gangrenosum possibly associated with sunitinib treatment","volume":"52","author":"Ueharaguchi","year":"2013","journal-title":"Int J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0015|bjd15193-cit-0015","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/j.1365-2133.2008.08599.x","article-title":"Pyoderma gangrenosum: another cutaneous side-effect of sunitinib?","volume":"159","author":"Freyhaus","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0016|bjd15193-cit-0016","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1111\/jdv.13148","article-title":"Pyoderma gangrenosum of the penis possibly associated with pazopanib treatment","volume":"30","author":"Usui","year":"2016","journal-title":"J Eur Acad Dermatology Venereol"},{"key":"10.1111\/bjd.15193-BIB0017|bjd15193-cit-0017","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1684\/ejd.2014.2297","article-title":"Neutrophilic disease of the skin and intestines after ipilimumab treatment for malignant melanoma - simultaneous occurrence of pyoderma gangrenosum and colitis","volume":"24","author":"Rudolph","year":"2014","journal-title":"Eur J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0018|bjd15193-cit-0018","doi-asserted-by":"crossref","first-page":"629","DOI":"10.3109\/10428199709050901","article-title":"Bullous pyoderma gangrenosum in a patient with myelodysplastic syndrome during granulocyte colony-stimulating factor therapy","volume":"26","author":"Lewerin","year":"1997","journal-title":"Leuk Lymphoma"},{"key":"10.1111\/bjd.15193-BIB0019|bjd15193-cit-0019","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1002\/1097-0142(19910715)68:2<441::AID-CNCR2820680239>3.0.CO;2-4","article-title":"Bullous pyoderma gangrenosum after granulocyte colony-stimulating factor treatment","volume":"68","author":"Ross","year":"1991","journal-title":"Cancer"},{"key":"10.1111\/bjd.15193-BIB0020|bjd15193-cit-0020","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1540-9740.2006.04575.x","article-title":"Pyoderma gangrenosum related to a new granulocyte colony-stimulating factor","volume":"5","author":"White","year":"2006","journal-title":"Skinmed"},{"key":"10.1111\/bjd.15193-BIB0021|bjd15193-cit-0021","doi-asserted-by":"crossref","first-page":"316","DOI":"10.2169\/internalmedicine.37.316","article-title":"Pyoderma gangrenosum following cytosine arabinoside, aclarubicin and granulocyte colony-stimulating factor combination therapy in myelodysplastic syndrome","volume":"37","author":"Takagi","year":"1998","journal-title":"Intern Med"},{"key":"10.1111\/bjd.15193-BIB0022|bjd15193-cit-0022","first-page":"846","article-title":"Pyoderma gangrenosum aggravated by GM-CSF administration","volume":"119","author":"Perrot","year":"1992","journal-title":"Ann Dermatol Venereol"},{"key":"10.1111\/bjd.15193-BIB0023|bjd15193-cit-0023","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/j.1600-0560.1998.tb01741.x","article-title":"Histopathology of cutaneous reaction to granulocyte colony-stimulating factor: another pseudomalignancy","volume":"25","author":"Farina","year":"1998","journal-title":"J Cutan Pathol"},{"key":"10.1111\/bjd.15193-BIB0024|bjd15193-cit-0024","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1001\/archderm.1991.01680010059008","article-title":"Intravenous administration of recombinant human granulocyte-macrophage colony-stimulating factor causes a cutaneous eruption","volume":"127","author":"Horn","year":"1991","journal-title":"Arch Dermatol"},{"key":"10.1111\/bjd.15193-BIB0025|bjd15193-cit-0025","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1365-2141.2005.05839.x","article-title":"Pyoderma gangrenosum complicating pegylated granulocyte colony-stimulating factor in Hodgkin lymphoma","volume":"132","author":"Miall","year":"2006","journal-title":"Br J Haematol"},{"key":"10.1111\/bjd.15193-BIB0026|bjd15193-cit-0026","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3315\/jdcr.2012.1110","article-title":"Photoletter to the editor: Localized pyoderma gangrenosum after interferon-alpha2b injections","volume":"6","author":"Mir-Bonaf\u00e9","year":"2012","journal-title":"J Dermatol Case Rep"},{"key":"10.1111\/bjd.15193-BIB0027|bjd15193-cit-0027","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1097\/MEG.0b013e32816e070b","article-title":"Pyoderma gangrenosum and exacerbation of psoriasis resulting from pegylated interferon alpha and ribavirin treatment of chronic hepatitis C","volume":"19","author":"Yurci","year":"2007","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1111\/bjd.15193-BIB0028|bjd15193-cit-0028","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3109\/10428199809050944","article-title":"Pyoderma gangrenosum triggered by alpha2b-interferon in a patient with chronic granulocytic leukemia","volume":"30","author":"Montoto","year":"1998","journal-title":"Leuk Lymphoma"},{"key":"10.1111\/bjd.15193-BIB0029|bjd15193-cit-0029","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1001\/archderm.144.6.817","article-title":"Pyoderma gangrenosum in a patient with seronegative rheumatoid arthritis during therapy with adalimumab: toxic effects of adalimumab or failure of adalimumab to prevent the onset of this phenomenon?","volume":"144","author":"Stichenwirth","year":"2008","journal-title":"Arch Dermatol"},{"key":"10.1111\/bjd.15193-BIB0030|bjd15193-cit-0030","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1684\/ejd.2012.1849","article-title":"Pyoderma gangrenosum possibly triggered by adalimumab","volume":"22","author":"Kikuchi","year":"2012","journal-title":"Eur J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0031|bjd15193-cit-0031","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1007\/s10067-007-0733-8","article-title":"Pyoderma gangrenosum developing during therapy with TNF-alpha antagonists in a patient with rheumatoid arthritis","volume":"26","author":"Vandevyvere","year":"2007","journal-title":"Clin Rheumatol"},{"key":"10.1111\/bjd.15193-BIB0032|bjd15193-cit-0032","doi-asserted-by":"crossref","first-page":"183","DOI":"10.2340\/00015555-0777","article-title":"Paradoxical reactions to targeted biological treatments: a way to treat and trigger?","volume":"90","author":"Brunasso","year":"2010","journal-title":"Acta Derm Venereol"},{"key":"10.1111\/bjd.15193-BIB0033|bjd15193-cit-0033","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3315\/jdcr.2009.1027","article-title":"Development of pyoderma gangrenosum during therapy with infliximab","volume":"3","author":"Jaimes-L\u00f3pez","year":"2009","journal-title":"J Dermatol Case Rep"},{"key":"10.1111\/bjd.15193-BIB0034|bjd15193-cit-0034","first-page":"447","article-title":"Paradoxical reaction to etanercept: development of pyoderma gangraenosum during therapy of psoriasis arthritis","volume":"11","author":"Kowalzick","year":"2013","journal-title":"J Dtsch Dermatol Ges"},{"issue":"2 Pt 2","key":"10.1111\/bjd.15193-BIB0035|bjd15193-cit-0035","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0190-9622(84)80011-0","article-title":"Hydralazine-induced systemic lupus erythematosus presenting as pyoderma gangrenosum-like ulcers","volume":"10","author":"Peterson","year":"1984","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.15193-BIB0036|bjd15193-cit-0036","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1111\/bjd.13151","article-title":"Hydroxycarbamide-induced cutaneous ulceration with a difference","volume":"171","author":"Matthews","year":"2014","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0037|bjd15193-cit-0037","first-page":"253","article-title":"Suspected induction of a pyoderma gangrenosum-like eruption due to sulpiride treatment","volume":"67","author":"Srebrnik","year":"2001","journal-title":"Cutis"},{"key":"10.1111\/bjd.15193-BIB0038|bjd15193-cit-0038","doi-asserted-by":"crossref","first-page":"48","DOI":"10.5021\/ad.2010.22.1.48","article-title":"A case of p-ANCA-positive propylthiouracil-induced pyoderma gangrenosum","volume":"22","author":"Seo","year":"2010","journal-title":"Ann Dermatol"},{"key":"10.1111\/bjd.15193-BIB0039|bjd15193-cit-0039","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1046\/j.1440-0960.1999.00346.x","article-title":"Pyoderma gangrenosum with secondary pyarthrosis following propylthiouracil","volume":"40","author":"Darben","year":"1999","journal-title":"Australas J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0040|bjd15193-cit-0040","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1159\/000077844","article-title":"A case of propylthiouracil-induced pyoderma gangrenosum associated with antineutrophil cytoplasmic antibody","volume":"208","author":"Hong","year":"2004","journal-title":"Dermatology"},{"key":"10.1111\/bjd.15193-BIB0041|bjd15193-cit-0041","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/BF03344152","article-title":"ANCA positive propylthiouracil induced pyoderma gangrenosum","volume":"29","author":"Gungor","year":"2006","journal-title":"J Endocrinol Invest"},{"key":"10.1111\/bjd.15193-BIB0042|bjd15193-cit-0042","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/bjh.13341","article-title":"Pyoderma gangrenosum secondary to azacitidine in myelodysplastic syndrome","volume":"169","author":"Tseng","year":"2015","journal-title":"Br J Haematol"},{"key":"10.1111\/bjd.15193-BIB0043|bjd15193-cit-0043","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1097\/LGT.0000000000000043","article-title":"Vulvovaginal pyoderma gangrenosum secondary to rituximab therapy","volume":"19","author":"Dixit","year":"2015","journal-title":"J Low Genit Tract Dis"},{"key":"10.1111\/bjd.15193-BIB0044|bjd15193-cit-0044","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.jaad.2015.11.040","article-title":"Pyoderma gangrenosum (PG) associated with levamisole-adulterated cocaine: clinical, serologic, and histopathologic findings in a cohort of patients","volume":"74","author":"Jeong","year":"2016","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.15193-BIB0045|bjd15193-cit-0045","first-page":"727","article-title":"Two cases of eruptive pyoderma gangrenosum associated with cocaine use","volume":"99","author":"Roche","year":"2008","journal-title":"Actas Dermo-Sifiliogr\u00e1ficas (English edn)"},{"key":"10.1111\/bjd.15193-BIB0046|bjd15193-cit-0046","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1503\/cmaj.140122","article-title":"Pyoderma gangrenosum triggered by red tattoo dye","volume":"186","author":"Litvinov","year":"2014","journal-title":"CMAJ"},{"key":"10.1111\/bjd.15193-BIB0047|bjd15193-cit-0047","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/bjd.14230","article-title":"Pyoderma gangrenosum and pregnancy: an example of abnormal inflammation and challenging treatment","volume":"174","author":"Steele","year":"2016","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0048|bjd15193-cit-0048","doi-asserted-by":"crossref","first-page":"300","DOI":"10.4172\/2155-9864.1000300","article-title":"Sweet's syndrome as a possible consequence of azacitidine subcutaneous administration in IPSS intermediate-2 myelodysplastic syndrome","volume":"6","author":"Troccola","year":"2015","journal-title":"J Blood Disord Transfus"},{"key":"10.1111\/bjd.15193-BIB0049|bjd15193-cit-0049","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/cei.12394","article-title":"Expression of cytokines, chemokines and other effector molecules in two prototypic autoinflammatory skin diseases, pyoderma gangrenosum and Sweet's syndrome","volume":"178","author":"Marzano","year":"2014","journal-title":"Clin Exp Immunol"},{"key":"10.1111\/bjd.15193-BIB0050|bjd15193-cit-0050","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1001\/archdermatol.2011.168","article-title":"Interleukin 23 expression in pyoderma gangrenosum and targeted therapy with ustekinumab","volume":"147","author":"Guenova","year":"2011","journal-title":"Arch Dermatol"},{"key":"10.1111\/bjd.15193-BIB0051|bjd15193-cit-0051","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/j.1365-2249.2010.04201.x","article-title":"Role of inflammatory cells, cytokines and matrix metalloproteinases in neutrophil-mediated skin diseases","volume":"162","author":"Marzano","year":"2010","journal-title":"Clin Exp Immunol"},{"key":"10.1111\/bjd.15193-BIB0052|bjd15193-cit-0052","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1111\/j.1600-0560.2007.00744.x","article-title":"Expression of MMP-9, MMP-10 and TNF-alpha and lack of epithelial MMP-1 and MMP-26 characterize pyoderma gangrenosum","volume":"34","author":"Bister","year":"2007","journal-title":"J Cutan Pathol"},{"key":"10.1111\/bjd.15193-BIB0053|bjd15193-cit-0053","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1111\/j.1468-3083.2009.03199.x","article-title":"Pyoderma gangrenosum: an updated review","volume":"23","author":"Ruocco","year":"2009","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1111\/bjd.15193-BIB0054|bjd15193-cit-0054","first-page":"329","article-title":"Management of pyoderma gangrenosum - an update","volume":"70","author":"Bhat","year":"2004","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.1111\/bjd.15193-BIB0055|bjd15193-cit-0055","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1097\/01.MIB.0000442011.60285.68","article-title":"Clinical, serologic, and genetic factors associated with pyoderma gangrenosum and erythema nodosum in inflammatory bowel disease patients","volume":"20","author":"Weizman","year":"2014","journal-title":"Inflamm Bowel Dis"},{"key":"10.1111\/bjd.15193-BIB0056|bjd15193-cit-0056","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1172\/JCI106754","article-title":"Chemotaxis of polymorphonuclear leukocytes from patients with rheumatoid arthritis","volume":"50","author":"Mowat","year":"1971","journal-title":"J Clin Invest"},{"key":"10.1111\/bjd.15193-BIB0057|bjd15193-cit-0057","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1053\/j.gastro.2007.10.031","article-title":"Colonic neutrophils in inflammatory bowel disease: double-edged swords of the innate immune system with protective and destructive capacity","volume":"133","author":"Williams","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1111\/bjd.15193-BIB0058|bjd15193-cit-0058","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1001\/archderm.1976.01630370072023","article-title":"Pyoderma gangrenosum, defective neutrophil chemotaxis, and leukemia","volume":"112","author":"Shore","year":"1976","journal-title":"Arch Dermatol"},{"key":"10.1111\/bjd.15193-BIB0059|bjd15193-cit-0059","first-page":"209","article-title":"New look at pyoderma gangrenosum","volume":"20","author":"Shore","year":"1977","journal-title":"Cutis"},{"key":"10.1111\/bjd.15193-BIB0060|bjd15193-cit-0060","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1111\/j.1365-2133.1982.tb11684.x","article-title":"Pharmacological modulation of neutrophil phagocytic function in a patient with recurrent sepsis, pyoderma gangrenosum and impaired phagocytosis","volume":"106","author":"Bentley-Phillips","year":"1982","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0061|bjd15193-cit-0061","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1093\/rheumatology\/37.11.1148","article-title":"Skin hyperreactivity of Beh\u00e7et's patients (pathergy reaction) is also positive in interferon alpha-treated chronic myeloid leukaemia patients, indicating similarly altered neutrophil functions in both disorders","volume":"37","author":"Budak-Alpdogan","year":"1998","journal-title":"Br J Rheumatol"},{"key":"10.1111\/bjd.15193-BIB0062|bjd15193-cit-0062","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1046\/j.1523-1747.1998.00311.x","article-title":"Aberrant neutrophil trafficking and metabolic oscillations in severe pyoderma gangrenosum","volume":"111","author":"Adachi","year":"1998","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.15193-BIB0063|bjd15193-cit-0063","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2353\/ajpath.2008.070502","article-title":"Mechanisms and consequences of neutrophil interaction with the endothelium","volume":"172","author":"Zarbock","year":"2008","journal-title":"Am J Pathol"},{"key":"10.1111\/bjd.15193-BIB0064|bjd15193-cit-0064","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1111\/j.1365-2133.2007.08202.x","article-title":"Pyoderma gangrenosum and interleukin 8","volume":"157","author":"Oka","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0065|bjd15193-cit-0065","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1046\/j.1365-2133.1998.02567.x","article-title":"Pyoderma gangrenosum in a child with congenital partial deficiency of leucocyte adherence glycoproteins","volume":"139","author":"Bedlow","year":"1998","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0066|bjd15193-cit-0066","doi-asserted-by":"crossref","first-page":"158","DOI":"10.4103\/0019-5154.108076","article-title":"Leukocyte adhesion defect type 1 presenting with recurrent pyoderma gangrenosum","volume":"58","author":"Thakur","year":"2013","journal-title":"Indian J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0067|bjd15193-cit-0067","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/j.1744-9987.2005.00284.x","article-title":"Treatment of pyoderma gangrenosum with granulocyte and monocyte adsorption apheresis","volume":"9","author":"Kanekura","year":"2005","journal-title":"Ther Apher Dial"},{"key":"10.1111\/bjd.15193-BIB0068|bjd15193-cit-0068","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1744-9987.2007.00498.x","article-title":"A case report of steroid and immunosuppressant-resistant pyoderma gangrenosum successfully treated by granulocytapheresis","volume":"11","author":"Okuma","year":"2007","journal-title":"Ther Apher Dial"},{"key":"10.1111\/bjd.15193-BIB0069|bjd15193-cit-0069","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1744-9987.2007.00424.x","article-title":"Efficacy of granulocyte and monocyte adsorption apheresis for three cases of refractory pyoderma gangrenosum","volume":"11","author":"Seishima","year":"2007","journal-title":"Ther Apher Dial"},{"key":"10.1111\/bjd.15193-BIB0070|bjd15193-cit-0070","doi-asserted-by":"crossref","first-page":"275","DOI":"10.2340\/00015555-2507","article-title":"Pyoderma gangrenosum, acne and suppurative hidradenitis syndrome treated with granulocyte and monocyte adsorption apheresis","volume":"97","author":"Mizutani","year":"2017","journal-title":"Acta Derm Venereol"},{"key":"10.1111\/bjd.15193-BIB0071|bjd15193-cit-0071","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1001\/archderm.140.5.570","article-title":"Elevated serum granulocyte colony-stimulating factor levels in patients with active phase of Sweet syndrome and patients with active Beh\u00e7et disease: implication in neutrophil apoptosis dysfunction","volume":"140","author":"Kawakami","year":"2004","journal-title":"Arch Dermatol"},{"key":"10.1111\/bjd.15193-BIB0072|bjd15193-cit-0072","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1111\/j.1346-8138.2010.01009.x","article-title":"Clinical implications of leukocytapheresis using a centrifugal cell separator for steroid-resistant pyoderma gangrenosum associated with inflammatory bowel disease","volume":"38","author":"Hanafusa","year":"2011","journal-title":"J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0073|bjd15193-cit-0073","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1111\/j.1346-8138.2008.00572.x","article-title":"Leukocyte adsorption apheresis for the treatment of pyoderma gangrenosum","volume":"35","author":"Watanabe","year":"2008","journal-title":"J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0074|bjd15193-cit-0074","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1111\/j.1365-2133.2004.06249.x","article-title":"Leukocytapheresis treatment for pyoderma gangrenosum","volume":"151","author":"Fujimoto","year":"2004","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0075|bjd15193-cit-0075","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.arr.2015.01.003","article-title":"DAMPs as mediators of sterile inflammation in aging-related pathologies","volume":"24","author":"Feldman","year":"2015","journal-title":"Ageing Res Rev"},{"key":"10.1111\/bjd.15193-BIB0076|bjd15193-cit-0076","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/nature14191","article-title":"Necroptosis and its role in inflammation","volume":"517","author":"Pasparakis","year":"2015","journal-title":"Nature"},{"key":"10.1111\/bjd.15193-BIB0077|bjd15193-cit-0077","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.tig.2007.05.008","article-title":"Epigenetics and aging: the targets and the marks","volume":"23","author":"Fraga","year":"2007","journal-title":"Trends Genet"},{"key":"10.1111\/bjd.15193-BIB0078|bjd15193-cit-0078","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s12033-009-9216-2","article-title":"DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker","volume":"44","author":"Tost","year":"2010","journal-title":"Mol Biotechnol"},{"key":"10.1111\/bjd.15193-BIB0079|bjd15193-cit-0079","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/jn\/135.1.5","article-title":"Nutrition and aberrant DNA methylation patterns in atherosclerosis: more than just hyperhomocysteinemia?","volume":"135","author":"Zaina","year":"2005","journal-title":"J Nutr"},{"key":"10.1111\/bjd.15193-BIB0080|bjd15193-cit-0080","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1161\/HYPERTENSIONAHA.111.188730","article-title":"Reduced methylation of the thromboxane synthase gene is correlated with its increased vascular expression in preeclampsia","volume":"59","author":"Mousa","year":"2012","journal-title":"Hypertension"},{"key":"10.1111\/bjd.15193-BIB0081|bjd15193-cit-0081","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nrrheum.2014.128","article-title":"The role of genetics and epigenetics in the pathogenesis of systemic sclerosis","volume":"10","author":"Broen","year":"2014","journal-title":"Nat Rev Rheumatol"},{"key":"10.1111\/bjd.15193-BIB0082|bjd15193-cit-0082","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jaut.2014.07.002","article-title":"DNA methylation and mRNA and microRNA expression of SLE CD4+ T cells correlate with disease phenotype","volume":"54","author":"Zhao","year":"2014","journal-title":"J Autoimmun"},{"key":"10.1111\/bjd.15193-BIB0083|bjd15193-cit-0083","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jaut.2013.01.001","article-title":"Whole-genome DNA methylation in skin lesions from patients with psoriasis vulgaris","volume":"41","author":"Zhang","year":"2013","journal-title":"J Autoimmun"},{"key":"10.1111\/bjd.15193-BIB0084|bjd15193-cit-0084","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1093\/ndt\/gfq834","article-title":"ANCA vasculitis meets epigenetics - closing in on the molecular roots of disease","volume":"26","author":"Zeisberg","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"10.1111\/bjd.15193-BIB0085|bjd15193-cit-0085","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/BOR.0b013e32835b4449","article-title":"Rheumatic manifestations of cocaine use","volume":"25","author":"Graf","year":"2013","journal-title":"Curr Opin Rheumatol"},{"key":"10.1111\/bjd.15193-BIB0086|bjd15193-cit-0086","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1097\/BOR.0000000000000014","article-title":"Trojan horses: drug culprits associated with antineutrophil cytoplasmic autoantibody (ANCA) vasculitis","volume":"26","author":"Pendergraft","year":"2014","journal-title":"Curr Opin Rheumatol"},{"key":"10.1111\/bjd.15193-BIB0087|bjd15193-cit-0087","first-page":"317","article-title":"Influence of tetramisole and its optical isomers on the mononuclear phagocytic system. Effect on carbon clearance in mice","volume":"14","author":"Hoebeke","year":"1973","journal-title":"J Reticuloendothel Soc"},{"key":"10.1111\/bjd.15193-BIB0088|bjd15193-cit-0088","doi-asserted-by":"crossref","first-page":"428","DOI":"10.4049\/jimmunol.117.2.428","article-title":"In vitro stimulation of neutrophil motility by levamisole: maintenance of cGMP levels in chemotactically stimulated levamisole-treated neutrophils","volume":"117","author":"Anderson","year":"1976","journal-title":"J Immunol"},{"key":"10.1111\/bjd.15193-BIB0089|bjd15193-cit-0089","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1126\/science.1092385","article-title":"Neutrophil extracellular traps kill bacteria","volume":"303","author":"Brinkmann","year":"2004","journal-title":"Science"},{"key":"10.1111\/bjd.15193-BIB0090|bjd15193-cit-0090","first-page":"638","article-title":"Neutrophil extracellular traps as a potential source of autoantigen in cocaine-associated autoimmunity","volume":"56","author":"Lood","year":"2017","journal-title":"Rheumatology (Oxford)"},{"key":"10.1111\/bjd.15193-BIB0091|bjd15193-cit-0091","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/jps.2600810106","article-title":"Absolute bioavailability, rate of absorption, and dose proportionality of sulpiride in humans","volume":"81","author":"Bressolle","year":"1992","journal-title":"J Pharm Sci"},{"key":"10.1111\/bjd.15193-BIB0092|bjd15193-cit-0092","first-page":"1","article-title":"Adverse cutaneous reactions to psychotropic drugs","volume":"158","author":"Srebrnik","year":"1991","journal-title":"Acta Derm Venereol Suppl (Stockh)"},{"key":"10.1111\/bjd.15193-BIB0093|bjd15193-cit-0093","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s10517-014-2349-8","article-title":"Comparative evaluation of opioid-induced changes in immune reactivity of CBA mice","volume":"156","author":"Cheido","year":"2014","journal-title":"Bull Exp Biol Med"},{"key":"10.1111\/bjd.15193-BIB0094|bjd15193-cit-0094","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1056\/NEJM200104053441406","article-title":"Complement. First of two parts","volume":"344","author":"Walport","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1111\/bjd.15193-BIB0095|bjd15193-cit-0095","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1084\/jem.183.6.2533","article-title":"CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells","volume":"183","author":"Krummel","year":"1996","journal-title":"J Exp Med"},{"key":"10.1111\/bjd.15193-BIB0096|bjd15193-cit-0096","doi-asserted-by":"crossref","first-page":"5813","DOI":"10.4049\/jimmunol.162.10.5813","article-title":"CTLA-4-mediated inhibition of early events of T cell proliferation","volume":"162","author":"Brunner","year":"1999","journal-title":"J Immunol"},{"key":"10.1111\/bjd.15193-BIB0097|bjd15193-cit-0097","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/1479-5876-11-108","article-title":"The engagement of CTLA-4 on primary melanoma cell lines induces antibody-dependent cellular cytotoxicity and TNF-\u03b1 production","volume":"11","author":"Laurent","year":"2013","journal-title":"J Transl Med"},{"key":"10.1111\/bjd.15193-BIB0098|bjd15193-cit-0098","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1177\/039463200902200301","article-title":"Anti-TNF-alpha inhibitors: a new therapeutic approach for inflammatory immune-mediated diseases: an update upon efficacy and adverse events","volume":"22","author":"Murdaca","year":"2009","journal-title":"Int J Immunopathol Pharmacol"},{"key":"10.1111\/bjd.15193-BIB0099|bjd15193-cit-0099","doi-asserted-by":"crossref","first-page":"67","DOI":"10.2165\/00128071-200708020-00002","article-title":"The role of anti-tumor necrosis factor-alpha therapy in pyoderma gangrenosum associated with inflammatory bowel disease","volume":"8","author":"Reguia\u00ef","year":"2007","journal-title":"Am J Clin Dermatol"},{"key":"10.1111\/bjd.15193-BIB0100|bjd15193-cit-0100","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1111\/j.1365-4632.2007.03286.x","article-title":"Etanercept for the treatment of refractory pyoderma gangrenosum: a brief series","volume":"46","author":"Charles","year":"2007","journal-title":"Int J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0101|bjd15193-cit-0101","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.jaci.2013.05.036","article-title":"Infliximab induces downregulation of the IL-12\/IL-23 axis in 6-sulfo-LacNac (slan)+ dendritic cells and macrophages","volume":"132","author":"Brunner","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"10.1111\/bjd.15193-BIB0102|bjd15193-cit-0102","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2249.2010.04146.x","article-title":"How tumour necrosis factor blockers interfere with tuberculosis immunity","volume":"161","author":"Harris","year":"2010","journal-title":"Clin Exp Immunol"},{"key":"10.1111\/bjd.15193-BIB0103|bjd15193-cit-0103","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1002\/art.23835","article-title":"Psoriatic skin lesions induced by tumor necrosis factor antagonist therapy: a literature review and potential mechanisms of action","volume":"59","author":"Collamer","year":"2008","journal-title":"Arthritis Rheum"},{"key":"10.1111\/bjd.15193-BIB0104|bjd15193-cit-0104","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.clim.2010.02.004","article-title":"CD4+ T-cells lymphocytosis and reduction of neutrophils during treatment with adalimumab: challenge and dechallenge study","volume":"135","author":"Ursini","year":"2010","journal-title":"Clin Immunol"},{"key":"10.1111\/bjd.15193-BIB0105|bjd15193-cit-0105","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1146\/annurev.med.52.1.125","article-title":"Antibody-targeted immunotherapy for treatment of malignancy","volume":"52","author":"White","year":"2001","journal-title":"Annu Rev Med"},{"key":"10.1111\/bjd.15193-BIB0106|bjd15193-cit-0106","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1046\/j.1365-2141.2001.03166.x","article-title":"Complement activation plays a key role in the side-effects of rituximab treatment","volume":"115","author":"Kolk","year":"2001","journal-title":"Br J Haematol"},{"key":"10.1111\/bjd.15193-BIB0107|bjd15193-cit-0107","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1182\/blood-2002-03-0876","article-title":"An anti-C3b(i) mAb enhances complement activation, C3b(i) deposition, and killing of CD20+ cells by rituximab","volume":"101","author":"Kennedy","year":"2003","journal-title":"Blood"},{"key":"10.1111\/bjd.15193-BIB0108|bjd15193-cit-0108","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.4049\/jimmunol.171.3.1581","article-title":"Complement activation determines the therapeutic activity of rituximab in vivo","volume":"171","author":"Di Gaetano","year":"2003","journal-title":"J Immunol"},{"key":"10.1111\/bjd.15193-BIB0109|bjd15193-cit-0109","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1172\/JCI16577","article-title":"C5a anaphylatoxin is a major regulator of activating versus inhibitory FcgammaRs in immune complex-induced lung disease","volume":"110","author":"Shushakova","year":"2002","journal-title":"J Clin Invest"},{"key":"10.1111\/bjd.15193-BIB0110|bjd15193-cit-0110","first-page":"1324","article-title":"DNA methylation and demethylating drugs in myelodysplastic syndromes and secondary leukemias","volume":"87","author":"Leone","year":"2002","journal-title":"Haematologica"},{"key":"10.1111\/bjd.15193-BIB0111|bjd15193-cit-0111","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1080\/08916930802024145","article-title":"Epigenetics and T-cell immunity","volume":"41","author":"Sawalha","year":"2008","journal-title":"Autoimmunity"},{"key":"10.1111\/bjd.15193-BIB0112|bjd15193-cit-0112","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.jaut.2013.04.003","article-title":"Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in na\u00efve CD4+ T cells from lupus patients","volume":"43","author":"Coit","year":"2013","journal-title":"J Autoimmun"},{"key":"10.1111\/bjd.15193-BIB0113|bjd15193-cit-0113","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/art.38264","article-title":"Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sj\u00f6gren's syndrome","volume":"66","author":"Altorok","year":"2014","journal-title":"Arthritis Rheumatol"},{"key":"10.1111\/bjd.15193-BIB0114|bjd15193-cit-0114","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jaut.2012.12.005","article-title":"Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression","volume":"41","author":"Rica","year":"2013","journal-title":"J Autoimmun"},{"key":"10.1111\/bjd.15193-BIB0115|bjd15193-cit-0115","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jaut.2015.01.004","article-title":"Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils","volume":"58","author":"Coit","year":"2015","journal-title":"J Autoimmun"},{"key":"10.1111\/bjd.15193-BIB0116|bjd15193-cit-0116","doi-asserted-by":"crossref","first-page":"526","DOI":"10.4161\/cam.29712","article-title":"Rho GTPase isoforms in cell motility: don't fret, we have FRET","volume":"8","author":"Donnelly","year":"2014","journal-title":"Cell Adh Migr"},{"key":"10.1111\/bjd.15193-BIB0117|bjd15193-cit-0117","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0001-7310(09)72277-X","article-title":"Cutaneous adverse reactions to tattoos and piercings","volume":"100","author":"Mataix","year":"2009","journal-title":"Actas Dermosifiliogr"},{"key":"10.1111\/bjd.15193-BIB0118|bjd15193-cit-0118","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1097\/IOP.0b013e31828ad7b7","article-title":"Tattoo granuloma of the eyelid mimicking carcinoma","volume":"30","author":"Bee","year":"2014","journal-title":"Ophthal Plast Reconstr Surg"},{"key":"10.1111\/bjd.15193-BIB0119|bjd15193-cit-0119","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1177\/1066896911425487","article-title":"Cutaneous pseudolymphoma following tattoo application: report of two new cases of a potential lymphoma mimicker","volume":"20","author":"Camilot","year":"2012","journal-title":"Int J Surg Pathol"},{"key":"10.1111\/bjd.15193-BIB0120|bjd15193-cit-0120","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1111\/j.1365-2133.1991.tb04954.x","article-title":"Red tattoo reactions: X-ray microanalysis and patch-test studies","volume":"124","author":"Sowden","year":"1991","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0121|bjd15193-cit-0121","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.critrevonc.2014.01.002","article-title":"Systematic review of the side effects associated with tyrosine kinase inhibitors used in the treatment of gastrointestinal stromal tumours on behalf of the EORTC Quality of Life Group","volume":"91","author":"Sodergren","year":"2014","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1111\/bjd.15193-BIB0122|bjd15193-cit-0122","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1093\/jnci\/djj069","article-title":"BAY 43-9006 inhibition of oncogenic RET mutants","volume":"98","author":"Carlomagno","year":"2006","journal-title":"J Natl Cancer Inst"},{"key":"10.1111\/bjd.15193-BIB0123|bjd15193-cit-0123","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1517\/14656566.2013.758713","article-title":"Second-line treatments for the management of advanced renal cell carcinoma: systematic review and meta-analysis","volume":"14","author":"Larkin","year":"2013","journal-title":"Expert Opin Pharmacother"},{"key":"10.1111\/bjd.15193-BIB0124|bjd15193-cit-0124","doi-asserted-by":"crossref","first-page":"3846","DOI":"10.1172\/JCI31871","article-title":"Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas","volume":"117","author":"Gao","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1111\/bjd.15193-BIB0125|bjd15193-cit-0125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0102110","article-title":"Association of toxicity of sorafenib and sunitinib for human keratinocytes with inhibition of signal transduction and activator of transcription 3 (STAT3)","volume":"9","author":"Yamamoto","year":"2014","journal-title":"PLOS ONE"},{"key":"10.1111\/bjd.15193-BIB0126|bjd15193-cit-0126","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/jid.2014.218","article-title":"Fas\/Fas ligand mediates keratinocyte death in sunitinib-induced hand-foot skin reaction","volume":"134","author":"Yeh","year":"2014","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.15193-BIB0127|bjd15193-cit-0127","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1111\/j.1365-2141.1993.tb03083.x","article-title":"Sweet's syndrome associated with myelodysplasia: possible role of cytokines in the pathogenesis of the disease","volume":"84","author":"Reuss-Borst","year":"1993","journal-title":"Br J Haematol"},{"key":"10.1111\/bjd.15193-BIB0128|bjd15193-cit-0128","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1182\/blood.V88.8.2819.bloodjournal8882819","article-title":"Biologic and clinical effects of granulocyte colony-stimulating factor in normal individuals","volume":"88","author":"Anderlini","year":"1996","journal-title":"Blood"},{"key":"10.1111\/bjd.15193-BIB0129|bjd15193-cit-0129","first-page":"606","article-title":"Effects of recombinant human granulocyte colony-stimulating factor administration on neutrophil phenotype and functions","volume":"82","author":"Carulli","year":"1997","journal-title":"Haematologica"},{"key":"10.1111\/bjd.15193-BIB0130|bjd15193-cit-0130","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1111\/j.1537-2995.2007.01241.x","article-title":"Differences in functional activity and antigen expression of granulocytes primed in vivo with filgrastim, lenograstim, or pegfilgrastim","volume":"47","author":"Ribeiro","year":"2007","journal-title":"Transfusion"},{"key":"10.1111\/bjd.15193-BIB0131|bjd15193-cit-0131","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1182\/blood.V88.1.335.335","article-title":"Effect of recombinant granulocyte colony-stimulating factor on neutrophil kinetics in normal young and elderly humans","volume":"88","author":"Price","year":"1996","journal-title":"Blood"},{"key":"10.1111\/bjd.15193-BIB0132|bjd15193-cit-0132","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1182\/blood.V69.3.937.937","article-title":"Functional differentiation of normal human neutrophils","volume":"69","author":"Glasser","year":"1987","journal-title":"Blood"},{"key":"10.1111\/bjd.15193-BIB0133|bjd15193-cit-0133","doi-asserted-by":"crossref","first-page":"3897","DOI":"10.1073\/pnas.1114153109","article-title":"CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells","volume":"109","author":"Poppensieker","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1111\/bjd.15193-BIB0134|bjd15193-cit-0134","first-page":"505","article-title":"The EGF receptor - an essential regulator of multiple epidermal functions","volume":"10","author":"Jost","year":"2000","journal-title":"Eur J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0135|bjd15193-cit-0135","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1038\/sj.onc.1201657","article-title":"EGF receptor signaling inhibits keratinocyte apoptosis: evidence for mediation by Bcl-XL","volume":"16","author":"Stoll","year":"1998","journal-title":"Oncogene"},{"key":"10.1111\/bjd.15193-BIB0136|bjd15193-cit-0136","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1111\/1523-1747.ep12340759","article-title":"EGF-receptor tyrosine kinase inhibition induces keratinocyte growth arrest and terminal differentiation","volume":"109","author":"Peus","year":"1997","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.15193-BIB0137|bjd15193-cit-0137","doi-asserted-by":"crossref","first-page":"28","DOI":"10.12788\/j.sder.0060","article-title":"Dermatologic adverse events to chemotherapeutic agents, part 1: cytotoxics, epidermal growth factor receptors, multikinase inhibitors, and proteasome inhibitors","volume":"33","author":"Kyllo","year":"2014","journal-title":"Semin Cutan Med Surg"},{"key":"10.1111\/bjd.15193-BIB0138|bjd15193-cit-0138","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0002-9440(10)63654-1","article-title":"Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation","volume":"163","author":"Mascia","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1111\/bjd.15193-BIB0139|bjd15193-cit-0139","first-page":"873","article-title":"Zd 1839 \u2018Iressa\u2019","volume":"87","author":"Meric","year":"2000","journal-title":"Bull Cancer"},{"issue":"Suppl. 1","key":"10.1111\/bjd.15193-BIB0140|bjd15193-cit-0140","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2165\/00003495-200060001-00002","article-title":"Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy","volume":"60","author":"Raymond","year":"2000","journal-title":"Drugs"},{"key":"10.1111\/bjd.15193-BIB0141|bjd15193-cit-0141","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nbt1068","article-title":"A small molecule-kinase interaction map for clinical kinase inhibitors","volume":"23","author":"Fabian","year":"2005","journal-title":"Nat Biotechnol"},{"key":"10.1111\/bjd.15193-BIB0142|bjd15193-cit-0142","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1182\/blood-2005-02-0488","article-title":"Gefitinib induces myeloid differentiation of acute myeloid leukemia","volume":"106","author":"Stegmaier","year":"2005","journal-title":"Blood"},{"key":"10.1111\/bjd.15193-BIB0143|bjd15193-cit-0143","doi-asserted-by":"crossref","first-page":"44924","DOI":"10.1074\/jbc.M402115200","article-title":"Association of BAP31 with CD11b\/CD18. Potential role in intracellular trafficking of CD11b\/CD18 in neutrophils","volume":"279","author":"Zen","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1111\/bjd.15193-BIB0144|bjd15193-cit-0144","doi-asserted-by":"crossref","first-page":"e1004770","DOI":"10.1371\/journal.ppat.1004770","article-title":"Low doses of imatinib induce myelopoiesis and enhance host anti-microbial immunity","volume":"11","author":"Napier","year":"2015","journal-title":"PLOS PATHOG"},{"key":"10.1111\/bjd.15193-BIB0145|bjd15193-cit-0145","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.tcb.2003.11.003","article-title":"How do Abl family kinases regulate cell shape and movement?","volume":"14","author":"Hern\u00e1ndez","year":"2004","journal-title":"Trends Cell Biol"},{"key":"10.1111\/bjd.15193-BIB0146|bjd15193-cit-0146","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1189\/jlb.1012487","article-title":"c-Abl tyrosine kinase plays a critical role in \u03b22 integrin-dependent neutrophil migration by regulating Vav1 activity","volume":"93","author":"Tong","year":"2013","journal-title":"J Leukoc Biol"},{"key":"10.1111\/bjd.15193-BIB0147|bjd15193-cit-0147","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1507\/endocrj.49.329","article-title":"Prevalence of serum anti-myeloperoxidase antineutrophil cytoplasmic antibodies (MPO-ANCA) in patients with Graves\u2019 disease treated with propylthiouracil and thiamazole","volume":"49","author":"Wada","year":"2002","journal-title":"Endocr J"},{"key":"10.1111\/bjd.15193-BIB0148|bjd15193-cit-0148","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/S0090-9556(25)07126-0","article-title":"Oxidation of propylthiouracil to reactive metabolites by activated neutrophils","volume":"19","author":"Waldhauser","year":"1991","journal-title":"Implications for agranulocytosis. Drug Metab Dispos"},{"key":"10.1111\/bjd.15193-BIB0149|bjd15193-cit-0149","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0300-483X(96)03476-2","article-title":"Antibodies to myeloperoxidase in propylthiouracil-induced autoimmune disease in the cat","volume":"114","author":"Waldhauser","year":"1996","journal-title":"Toxicology"},{"key":"10.1111\/bjd.15193-BIB0150|bjd15193-cit-0150","doi-asserted-by":"crossref","first-page":"3779","DOI":"10.1002\/art.34619","article-title":"Abnormal conformation and impaired degradation of propylthiouracil-induced neutrophil extracellular traps: implications of disordered neutrophil extracellular traps in a rat model of myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculiti","volume":"64","author":"Nakazawa","year":"2012","journal-title":"Arthritis Rheum"},{"key":"10.1111\/bjd.15193-BIB0151|bjd15193-cit-0151","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1097\/MOH.0000000000000098","article-title":"The role of neutrophils in causing antineutrophil cytoplasmic autoantibody-associated vasculitis","volume":"22","author":"Schreiber","year":"2015","journal-title":"Curr Opin Hematol"},{"key":"10.1111\/bjd.15193-BIB0152|bjd15193-cit-0152","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1136\/ard.58.4.237","article-title":"Monocyte activation in patients with Wegener's granulomatosis","volume":"58","author":"Muller Kobold","year":"1999","journal-title":"Ann Rheum Dis"},{"key":"10.1111\/bjd.15193-BIB0153|bjd15193-cit-0153","doi-asserted-by":"crossref","first-page":"258","DOI":"10.3322\/canjclin.38.5.258","article-title":"The role of interferon in cancer therapy: a current perspective","volume":"38","author":"Goldstein","year":"1988","journal-title":"CA Cancer J Clin"},{"key":"10.1111\/bjd.15193-BIB0154|bjd15193-cit-0154","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1146\/annurev.immunol.17.1.189","article-title":"Natural killer cells in antiviral defense: function and regulation by innate cytokines","volume":"17","author":"Biron","year":"1999","journal-title":"Annu Rev Immunol"},{"key":"10.1111\/bjd.15193-BIB0155|bjd15193-cit-0155","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1084\/jem.20101664","article-title":"Type I interferon: friend or foe?","volume":"207","author":"Trinchieri","year":"2010","journal-title":"J Exp Med"},{"key":"10.1111\/bjd.15193-BIB0156|bjd15193-cit-0156","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1089\/jir.1995.15.235","article-title":"Normal mouse skin lymphocyte, Langerhans cell, and keratinocyte responses to intradermal injections of interferon-alpha and interferon-gamma","volume":"15","author":"Tong","year":"1995","journal-title":"J Interferon Cytokine Res"},{"issue":"4 Pt 2 Suppl.","key":"10.1111\/bjd.15193-BIB0157|bjd15193-cit-0157","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0190-9622(82)70051-9","article-title":"The effects of retinoids on neutrophil functions in vitro","volume":"6","author":"Camisa","year":"1982","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.15193-BIB0158|bjd15193-cit-0158","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1002\/jlb.66.6.989","article-title":"The individual regulation of granule protein mRNA levels during neutrophil maturation explains the heterogeneity of neutrophil granules","volume":"66","author":"Cowland","year":"1999","journal-title":"J Leukoc Biol"},{"key":"10.1111\/bjd.15193-BIB0159|bjd15193-cit-0159","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1189\/jlb.69.6.851","article-title":"Gelatinase B functions as regulator and effector in leukocyte biology","volume":"69","author":"Opdenakker","year":"2001","journal-title":"J Leukoc Biol"},{"key":"10.1111\/bjd.15193-BIB0160|bjd15193-cit-0160","doi-asserted-by":"crossref","first-page":"3340","DOI":"10.4049\/jimmunol.161.7.3340","article-title":"Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing","volume":"161","author":"Sch\u00f6nbeck","year":"1998","journal-title":"J Immunol"},{"key":"10.1111\/bjd.15193-BIB0161|bjd15193-cit-0161","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/j.0022-202X.2005.23848.x","article-title":"Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin","volume":"125","author":"Papakonstantinou","year":"2005","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.15193-BIB0162|bjd15193-cit-0162","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1111\/j.1365-2133.2008.08487.x","article-title":"Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial","volume":"158","author":"Ruzicka","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0163|bjd15193-cit-0163","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1111\/j.1365-2133.2012.11063.x","article-title":"Alitretinoin abrogates innate inflammation in palmoplantar pustular psoriasis","volume":"167","author":"Irla","year":"2012","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.15193-BIB0164|bjd15193-cit-0164","first-page":"CD004934","article-title":"Hydralazine for essential hypertension","volume":"11","author":"Kandler","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1111\/bjd.15193-BIB0165|bjd15193-cit-0165","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1172\/JCI40034","article-title":"Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis","volume":"120","author":"Ciavatta","year":"2010","journal-title":"J Clin Invest"},{"key":"10.1111\/bjd.15193-BIB0166|bjd15193-cit-0166","first-page":"263","article-title":"Pathogenesis of antineutrophil cytoplasmic autoantibody vasculitis","volume":"20","author":"Jennette","year":"2014","journal-title":"Nat Rev Rheumatol"},{"key":"10.1111\/bjd.15193-BIB0167|bjd15193-cit-0167","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1097\/01.ASN.0000135058.46193.72","article-title":"Circumvention of normal constraints on granule protein gene expression in peripheral blood neutrophils and monocytes of patients with antineutrophil cytoplasmic autoantibody-associated glomerulonephritis","volume":"15","author":"Yang","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/bjd.15193-BIB0168|bjd15193-cit-0168","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1056\/NEJM199505183322001","article-title":"Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia","volume":"332","author":"Charache","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1111\/bjd.15193-BIB0169|bjd15193-cit-0169","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/j.0736-8046.2004.21603.x","article-title":"Cutaneous adverse reactions to hydroxyurea in patients with intermediate thalassemia","volume":"21","author":"Zargari","year":"2004","journal-title":"Pediatr Dermatol"},{"key":"10.1111\/bjd.15193-BIB0170|bjd15193-cit-0170","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1097\/FPC.0b013e32833854d6","article-title":"Hydroxycarbamide stimulates the production of proinflammatory cytokines by endothelial cells: relevance to sickle cell disease","volume":"20","author":"Laurance","year":"2010","journal-title":"Pharmacogenet Genomics"},{"key":"10.1111\/bjd.15193-BIB0171|bjd15193-cit-0171","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1067\/mjd.2001.113471","article-title":"Skin and nail changes in children with sickle cell anemia receiving hydroxyurea therapy","volume":"44","author":"O'Branski","year":"2001","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.15193-BIB0172|bjd15193-cit-0172","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1001\/archderm.1975.01630140041002","article-title":"Skin changes secondary to hydroxyurea therapy","volume":"111","author":"Kennedy","year":"1975","journal-title":"Arch Dermatol"},{"key":"10.1111\/bjd.15193-BIB0173|bjd15193-cit-0173","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0190-9622(97)70276-7","article-title":"Hydroxyurea dermopathy: a unique lichenoid eruption complicating long-term therapy with hydroxyurea","volume":"36","author":"Daoud","year":"1997","journal-title":"J Am Acad Dermatol"},{"issue":"4 Pt 1","key":"10.1111\/bjd.15193-BIB0174|bjd15193-cit-0174","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/S0190-9622(89)80274-9","article-title":"Skin lesions simulating chronic dermatomyositis during long-term hydroxyurea therapy","volume":"21","author":"Richard","year":"1989","journal-title":"J Am Acad Dermatol"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbjd.15193","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbjd.15193","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/bjd.15193\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T15:19:12Z","timestamp":1749741552000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/177\/1\/72\/6601918"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,14]]},"references-count":174,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,7]]}},"URL":"https:\/\/doi.org\/10.1111\/bjd.15193","archive":["Portico"],"relation":{},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6,14]]}}}