{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T02:03:31Z","timestamp":1790042611815,"version":"4.0.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T00:00:00Z","timestamp":1525651200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T00:00:00Z","timestamp":1525651200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Dermatol"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1111\/bjd.16397","type":"journal-article","created":{"date-parts":[[2018,1,30]],"date-time":"2018-01-30T07:20:21Z","timestamp":1517296821000},"page":"208-209","source":"Crossref","is-referenced-by-count":7,"title":["Retrospective study of rapamycin or rapalog 0\u00b71% cream for facial angiofibromas in tuberous sclerosis complex: evaluation of treatment effectiveness and cost"],"prefix":"10.1093","volume":"179","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8508-6784","authenticated-orcid":false,"given":"S.","family":"Norrenberg","sequence":"first","affiliation":[{"name":"Department of Paediatrics; University Hospital; Centre Hospitalier Universitaire Vaudois; Chemin de Mont\u00e9tan 16 1007 Lausanne Switzerland"},{"name":"Department of Dermatology; University Hospital; Centre Hospitalier Universitaire Vaudois; Chemin de Mont\u00e9tan 16 1007 Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Masconi","sequence":"additional","affiliation":[{"name":"Golaz Chemist SA; Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Karamanou","sequence":"additional","affiliation":[{"name":"Department of Paediatrics; University Hospital; Centre Hospitalier Universitaire Vaudois; Chemin de Mont\u00e9tan 16 1007 Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Meylan","sequence":"additional","affiliation":[{"name":"Department of Paediatrics; University Hospital; Centre Hospitalier Universitaire Vaudois; Chemin de Mont\u00e9tan 16 1007 Lausanne Switzerland"},{"name":"Department of Dermatology; University Hospital; Centre Hospitalier Universitaire Vaudois; Chemin de Mont\u00e9tan 16 1007 Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Golaz","sequence":"additional","affiliation":[{"name":"Golaz Chemist SA; Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Christen-Zaech","sequence":"additional","affiliation":[{"name":"Department of Paediatrics; University Hospital; Centre Hospitalier Universitaire Vaudois; Chemin de Mont\u00e9tan 16 1007 Lausanne Switzerland"},{"name":"Department of Dermatology; University Hospital; Centre Hospitalier Universitaire Vaudois; Chemin de Mont\u00e9tan 16 1007 Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,5,7]]},"reference":[{"key":"10.1111\/bjd.16397-BIB0001|bjd16397-cit-0001","first-page":"CD011272","article-title":"Rapamycin and rapalogs for tuberous sclerosis complex","volume":"7","author":"Sasongko","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1111\/bjd.16397-BIB0002|bjd16397-cit-0002","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1440-0960.2011.00837.x","article-title":"Topical 0.1% rapamycin for angiofibromas in paediatric patients with tuberous sclerosis: a pilot study of four patients","volume":"53","author":"Foster","year":"2012","journal-title":"Australas J Dermatol"},{"key":"10.1111\/bjd.16397-BIB0003|bjd16397-cit-0003","first-page":"93","article-title":"Topical rapamycin in facial angiofibromas: patients satisfaction versus objective response, and a literature review","volume":"2","author":"Rodrigo-Nicol\u00e1s","year":"2014","journal-title":"Clin Dermatol"},{"key":"10.1111\/bjd.16397-BIB0004|bjd16397-cit-0004","doi-asserted-by":"crossref","first-page":"540","DOI":"10.4103\/0378-6323.163800","article-title":"Topical mTOR (mechanistic target of rapamycin) inhibitor therapy in facial angiofibroma","volume":"81","author":"Samanta","year":"2015","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.1111\/bjd.16397-BIB0005|bjd16397-cit-0005","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/jdv.12665","article-title":"Analysis of current data on the use of topical rapamycin in the treatment of facial angiofibromas in tuberous sclerosis complex","volume":"29","author":"Balestri","year":"2015","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1111\/bjd.16397-BIB0006|bjd16397-cit-0006","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.pediatrneurol.2016.04.003","article-title":"Topical use of mammalian target of rapamycin (mTOR) inhibitors in tuberous sclerosis complex - a comprehensive review of literature","volume":"61","author":"J\u00f3zwiak","year":"2016","journal-title":"Pediatr Neurol"},{"key":"10.1111\/bjd.16397-BIB0007|bjd16397-cit-0007","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1001\/jamadermatol.2016.3545","article-title":"Efficacy and safety of topical sirolimus therapy for facial angiofibromas in the tuberous sclerosis complex: a randomized clinical trial","volume":"153","author":"Wataya-Kaneda","year":"2017","journal-title":"JAMA Dermatol"},{"key":"10.1111\/bjd.16397-BIB0008|bjd16397-cit-0008","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1111\/ced.12398","article-title":"Facial Angiofibroma Severity Index (FASI): reliability assessment of a new tool developed to measure severity and responsiveness to therapy in tuberous sclerosis-associated facial angiofibroma","volume":"39","author":"Salido-Vallejo","year":"2014","journal-title":"Clin Exp Dermatol"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbjd.16397","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/bjd.16397\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T13:39:29Z","timestamp":1676381969000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/179\/1\/208\/6732331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,7]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,7]]}},"URL":"https:\/\/doi.org\/10.1111\/bjd.16397","archive":["Portico"],"relation":{},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[2018,5,7]]}}}