{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:48:08Z","timestamp":1791895688020,"version":"4.3.4"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2018,8,16]],"date-time":"2018-08-16T00:00:00Z","timestamp":1534377600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2018,8,16]],"date-time":"2018-08-16T00:00:00Z","timestamp":1534377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Dermatol"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1111\/bjd.16680","type":"journal-article","created":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T00:37:56Z","timestamp":1523925476000},"page":"906-917","source":"Crossref","is-referenced-by-count":56,"title":["Atrophic scar formation in patients with acne involves long-acting immune responses with plasma cells and alteration of sebaceous glands"],"prefix":"10.1093","volume":"179","author":[{"given":"I.","family":"Carlavan","sequence":"first","affiliation":[{"name":"Galderma R&D; Biot France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Bertino","sequence":"additional","affiliation":[{"name":"Galderma R&D; Biot France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Rivier","sequence":"additional","affiliation":[{"name":"Galderma R&D; Biot France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Martel","sequence":"additional","affiliation":[{"name":"Galderma R&D; Biot France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Bourdes","sequence":"additional","affiliation":[{"name":"Galderma R&D; Biot France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Motte","sequence":"additional","affiliation":[{"name":"Galderma R&D; Biot France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"D\u00e9ret","sequence":"additional","affiliation":[{"name":"Galderma R&D; Biot France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Reiniche","sequence":"additional","affiliation":[{"name":"Galderma R&D; Biot France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Menigot","sequence":"additional","affiliation":[{"name":"Galderma R&D; Biot France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Khammari","sequence":"additional","affiliation":[{"name":"Onco-dermatology Department; CHU Nantes, CIC1413, CRCINA, University Nantes; Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5574-5825","authenticated-orcid":false,"given":"B.","family":"Dreno","sequence":"additional","affiliation":[{"name":"Onco-dermatology Department; CHU Nantes, CIC1413, CRCINA, University Nantes; Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Fogel","sequence":"additional","affiliation":[{"name":"132 Rue d'Assas 75006 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5418-3370","authenticated-orcid":false,"given":"J.J.","family":"Voegel","sequence":"additional","affiliation":[{"name":"Galderma R&D; Biot France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,8,16]]},"reference":[{"key":"10.1111\/bjd.16680-BIB0001|bjd16680-cit-0001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1067\/mjd.2003.618","article-title":"Management of acne: a report from a global alliance to improve outcomes in acne","volume":"49","author":"Gollnick","year":"2003","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.16680-BIB0002|bjd16680-cit-0002","first-page":"1","article-title":"From new findings in acne pathogenesis to new approaches in treatment","volume":"29","author":"Gollnick","year":"2015","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1111\/bjd.16680-BIB0003|bjd16680-cit-0003","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1525-1470.1991.tb00856.x","article-title":"Psychologic aspects of acne","volume":"8","author":"Koo","year":"1991","journal-title":"Pediatr Dermatol"},{"key":"10.1111\/bjd.16680-BIB0004|bjd16680-cit-0004","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1365-2230.1994.tb01200.x","article-title":"A clinical evaluation of acne scarring and its incidence","volume":"19","author":"Layton","year":"1994","journal-title":"Clin Exp Dermatol"},{"key":"10.1111\/bjd.16680-BIB0005|bjd16680-cit-0005","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1067\/mjd.2001.113451","article-title":"Acne scarring: a classification system and review of treatment options","volume":"45","author":"Jacob","year":"2001","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.16680-BIB0006|bjd16680-cit-0006","first-page":"1175","article-title":"The management of postacne scarring","volume":"33","author":"Goodman","year":"2007","journal-title":"Dermatol Surg"},{"key":"10.1111\/bjd.16680-BIB0007|bjd16680-cit-0007","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaad.2011.05.055","article-title":"Cutaneous scarring: pathophysiology, molecular mechanisms, and scar reduction therapeutics Part I. The molecular basis of scar formation","volume":"66","author":"Profyris","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.16680-BIB0008|bjd16680-cit-0008","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jaad.2011.08.035","article-title":"Cutaneous scarring: pathophysiology, molecular mechanisms, and scar reduction therapeutics Part II. Strategies to reduce scar formation after dermatologic procedures","volume":"66","author":"Tziotzios","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/bjd.16680-BIB0009|bjd16680-cit-0009","doi-asserted-by":"crossref","first-page":"135","DOI":"10.2165\/00128071-200102030-00002","article-title":"Optimal management of acne to prevent scarring and psychological sequelae","volume":"2","author":"Layton","year":"2001","journal-title":"Am J Clin Dermatol"},{"key":"10.1111\/bjd.16680-BIB0010|bjd16680-cit-0010","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1365-2133.2004.05749.x","article-title":"Inflammation in acne scarring: a comparison of the responses in lesions from patients prone and not prone to scar","volume":"150","author":"Holland","year":"2004","journal-title":"Br J Dermatol"},{"key":"10.1111\/bjd.16680-BIB0011|bjd16680-cit-0011","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.sder.2005.03.004","article-title":"The role of inflammation in the pathogenesis of acne and acne scarring","volume":"24","author":"Holland","year":"2005","journal-title":"Semin Cutan Med Surg"},{"key":"10.1111\/bjd.16680-BIB0012|bjd16680-cit-0012","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1046\/j.1523-1747.2003.12321.x","article-title":"Inflammatory events are involved in acne lesion initiation","volume":"121","author":"Jeremy","year":"2003","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.16680-BIB0013|bjd16680-cit-0013","first-page":"566","article-title":"Prospective study of pathogenesis of atrophic acne scars and role of macular erythema","volume":"16","author":"Tan","year":"2017","journal-title":"J Drugs Dermatol"},{"key":"10.1111\/bjd.16680-BIB0014|bjd16680-cit-0014","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1468-3083.2011.04330.x","article-title":"Serial sections of atrophic acne scars help in the interpretation of microscopic findings and the selection of good therapeutic modalities","volume":"27","author":"Lee","year":"2013","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1111\/bjd.16680-BIB0015|bjd16680-cit-0015","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1684\/ejd.2015.2713","article-title":"Different cutaneous innate immunity profiles in acne patients with and without atrophic scars","volume":"26","author":"Saint-Jean","year":"2016","journal-title":"Eur J Dermatol"},{"key":"10.1111\/bjd.16680-BIB0016|bjd16680-cit-0016","first-page":"136","article-title":"[ECLA grading: a system of acne classification for every day dermatological practice]","volume":"126","author":"Dreno","year":"1999","journal-title":"Ann Dermatol Venereol"},{"key":"10.1111\/bjd.16680-BIB0017|bjd16680-cit-0017","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1038\/44565","article-title":"Learning the parts of objects by non-negative matrix factorization","volume":"401","author":"Lee","year":"1999","journal-title":"Nature"},{"key":"10.1111\/bjd.16680-BIB0018|bjd16680-cit-0018","doi-asserted-by":"crossref","first-page":"509","DOI":"10.3390\/ijerph13050509","article-title":"Applications of a novel clustering approach using non-negative matrix factorization to environmental research in public health","volume":"13","author":"Fogel","year":"2016","journal-title":"Int J Environ Res Public Health"},{"key":"10.1111\/bjd.16680-BIB0019|bjd16680-cit-0019","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1109\/TPAMI.2008.277","article-title":"Convex and semi-nonnegative matrix factorizations","volume":"32","author":"Ding","year":"2010","journal-title":"IEEE Trans Pattern Anal Mach Intell"},{"key":"10.1111\/bjd.16680-BIB0020|bjd16680-cit-0020","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.cell.2010.02.029","article-title":"Nonresolving inflammation","volume":"140","author":"Nathan","year":"2010","journal-title":"Cell"},{"issue":"118-29","key":"10.1111\/bjd.16680-BIB0021|bjd16680-cit-0021","first-page":"e5","article-title":"Diverse activation and differentiation of multiple B-cell subsets in patients with atopic dermatitis but not in patients with psoriasis","volume":"137","author":"Czarnowicki","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.1111\/bjd.16680-BIB0022|bjd16680-cit-0022","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1038\/jid.2011.198","article-title":"Skin as a peripheral lymphoid organ: revisiting the concept of skin-associated lymphoid tissues","volume":"131","author":"Egawa","year":"2011","journal-title":"J Invest Dermatol"},{"key":"10.1111\/bjd.16680-BIB0023|bjd16680-cit-0023","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.jaci.2007.11.016","article-title":"Anti-CD20 (rituximab) treatment improves atopic eczema","volume":"121","author":"Simon","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1111\/bjd.16680-BIB0024|bjd16680-cit-0024","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1002\/art.22811","article-title":"Development of psoriasis after B cell depletion with rituximab","volume":"56","author":"Dass","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1111\/bjd.16680-BIB0025|bjd16680-cit-0025","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.it.2014.12.006","article-title":"Revisiting the role of B cells in skin immune surveillance","volume":"36","author":"Egbuniwe","year":"2015","journal-title":"Trends Immunol"},{"key":"10.1111\/bjd.16680-BIB0026|bjd16680-cit-0026","doi-asserted-by":"crossref","first-page":"R168","DOI":"10.1186\/ar4352","article-title":"B lymphocytes and B-cell activating factor promote collagen and profibrotic markers expression by dermal fibroblasts in systemic sclerosis","volume":"15","author":"Fran\u00e7ois","year":"2013","journal-title":"Arthritis Res Ther"},{"key":"10.1111\/bjd.16680-BIB0027|bjd16680-cit-0027","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF01607163","article-title":"Comparative immunohistochemical study of herpes simplex and varicella-zoster infections","volume":"422","author":"Nikkels","year":"1993","journal-title":"Virchows Arch A Pathol Anat Histopathol"},{"key":"10.1111\/bjd.16680-BIB0028|bjd16680-cit-0028","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.jaad.2003.10.672","article-title":"The scarring mechanism of smallpox","volume":"50","author":"Regan","year":"2004","journal-title":"J Am Acad Dermatol"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbjd.16680","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/bjd.16680\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T08:41:11Z","timestamp":1676364071000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/179\/4\/906\/6753793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,16]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,10]]}},"URL":"https:\/\/doi.org\/10.1111\/bjd.16680","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.733069036.793555895","asserted-by":"object"}]},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8,16]]}}}