{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T18:36:30Z","timestamp":1785263790304,"version":"3.55.0"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"},{"start":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T00:00:00Z","timestamp":1632182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Background<\/jats:p>\n               <jats:p>Cutaneous reactions after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are poorly characterized.<\/jats:p>\n               <jats:p>Objective<\/jats:p>\n               <jats:p>To describe and classify cutaneous reactions after SARS-CoV-2 vaccination.<\/jats:p>\n               <jats:p>Methods<\/jats:p>\n               <jats:p>A nationwide Spanish cross-sectional study was conducted. We included patients with cutaneous reactions within 21 days of any dose of the approved vaccines at the time of the study. After a face-to-face visit with a dermatologist, information on cutaneous reactions was collected via an online professional survey and clinical photographs were sent by email. Investigators searched for consensus on clinical patterns and classification.<\/jats:p>\n               <jats:p>Results<\/jats:p>\n               <jats:p>From 16 February to 15 May 2021, we collected 405 reactions after vaccination with the BNT162b2 (Pfizer-BioNTech; 40\u00b72%), mRNA-1273 (Moderna; 36\u00b73%) and AZD1222 (AstraZeneca; 23\u00b75%) vaccines. Mean patient age was 50\u00b77 years and 80\u00b72% were female. Cutaneous reactions were classified as injection site (\u2018COVID arm\u2019, 32\u00b71%), urticaria (14\u00b76%), morbilliform (8\u00b79%), papulovesicular (6\u00b74%), pityriasis rosea-like (4\u00b79%) and purpuric (4%) reactions. Varicella zoster and herpes simplex virus reactivations accounted for 13\u00b78% of reactions. The COVID arm was almost exclusive to women (95\u00b74%). The most reported reactions in each vaccine group were COVID arm (mRNA-1273, Moderna, 61\u00b79%), varicella zoster virus reactivation (BNT162b2, Pfizer-BioNTech, 17\u00b72%) and urticaria (AZD1222, AstraZeneca, 21\u00b71%). Most reactions to the mRNA-1273 (Moderna) vaccine were described in women (90\u00b75%). Eighty reactions (21%) were classified as severe\/very severe and 81% required treatment.<\/jats:p>\n               <jats:p>Conclusions<\/jats:p>\n               <jats:p>Cutaneous reactions after SARS-CoV-2 vaccination are heterogeneous. Most are mild-to-moderate and self-limiting, although severe\/very severe reactions are reported. Knowledge of these reactions during mass vaccination may help healthcare professionals and reassure patients.<\/jats:p>","DOI":"10.1111\/bjd.20639","type":"journal-article","created":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T08:43:33Z","timestamp":1626165813000},"page":"142-152","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":185,"title":["Cutaneous reactions after SARS-CoV-2 vaccination: a cross-sectional Spanish nationwide study of 405 cases"],"prefix":"10.1093","volume":"186","author":[{"given":"A.","family":"Catal\u00e0","sequence":"first","affiliation":[{"name":"Servicio de Dermatolog\u00eda Hospital Cl\u00ednic Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3721-8030","authenticated-orcid":false,"given":"C.","family":"Mu\u00f1oz-Santos","sequence":"additional","affiliation":[{"name":"Servicio de Dermatolog\u00eda Hospital General de Granollers 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