{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T23:37:54Z","timestamp":1787701074597,"version":"build-2784847793"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"},{"start":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:00:00Z","timestamp":1657843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p\/>","DOI":"10.1111\/bjd.21701","type":"journal-article","created":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T09:44:32Z","timestamp":1654508672000},"page":"793-795","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Ixekizumab rapidly improves inflammatory markers in patients with generalized pustular psoriasis"],"prefix":"10.1093","volume":"187","author":[{"given":"Makoto","family":"Ito","sequence":"first","affiliation":[{"name":"Department of Dermatology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0976-4982","authenticated-orcid":false,"given":"Masahiro","family":"Kamata","sequence":"additional","affiliation":[{"name":"Department of Dermatology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Dermatology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shota","family":"Egawa","sequence":"additional","affiliation":[{"name":"Department of Dermatology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayumi","family":"Nagata","sequence":"additional","affiliation":[{"name":"Department of Dermatology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saki","family":"Fukaya","sequence":"additional","affiliation":[{"name":"Department of Dermatology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsuko","family":"Fukuyasu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takamitsu","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Dermatology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeko","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Department of Dermatology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3743-135X","authenticated-orcid":false,"given":"Yayoi","family":"Tada","sequence":"additional","affiliation":[{"name":"Department of Dermatology Teikyo University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,11,1]]},"reference":[{"key":"2023010808123205500_bjd21701-bib-0001","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1111\/1346-8138.14523","article-title":"Japanese guidelines for the management and treatment of generalized pustular psoriasis: the new pathogenesis and treatment of GPP","volume":"45","author":"Fujita","year":"2018","journal-title":"J Dermatol"},{"key":"2023010808123205500_bjd21701-bib-0002","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/jdv.15416","article-title":"Long-term efficacy of ixekizumab in erythrodermic and generalized pustular psoriasis patients","volume":"33","author":"Egawa","year":"2019","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2023010808123205500_bjd21701-bib-0003","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/jdv.15287","article-title":"Long-term efficacy and safety of ixekizumab in Japanese patients with erythrodermic or generalized pustular psoriasis: subgroup analyses of an open-label, phase 3 study (UNCOVER-J)","volume":"33","author":"Okubo","year":"2019","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2023010808123205500_bjd21701-bib-0004","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.jaad.2019.09.040","article-title":"Real-world single-center experience with 10 cases of generalized pustular psoriasis successfully treated with ixekizumab","volume":"82","author":"Nagata","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"2023010808123205500_bjd21701-bib-0005","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.jaad.2012.09.037","article-title":"Therapeutic depletion of myeloid lineage leukocytes in patients with generalized pustular psoriasis indicates a major role for neutrophils in the immunopathogenesis of psoriasis","volume":"68","author":"Ikeda","year":"2013","journal-title":"J Am Acad Dermatol"},{"key":"2023010808123205500_bjd21701-bib-0006","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaad.2022.03.001","article-title":"A real-world, single-center experience and the immediate impact of granulocyte and monocyte adsorption apheresis on generalized pustular psoriasis","author":"Uchida","year":"2022","journal-title":"J Am Acad Dermatol"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjd.21701","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bjd.21701","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjd\/article-pdf\/187\/5\/793\/48529417\/bjd0793.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjd\/article-pdf\/187\/5\/793\/48529417\/bjd0793.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T14:13:32Z","timestamp":1676384012000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/187\/5\/793\/6966461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,1]]},"references-count":6,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,11,1]]},"published-print":{"date-parts":[[2022,11,1]]}},"URL":"https:\/\/doi.org\/10.1111\/bjd.21701","relation":{},"ISSN":["1365-2133","0007-0963"],"issn-type":[{"value":"1365-2133","type":"electronic"},{"value":"0007-0963","type":"print"}],"subject":[],"published-other":{"date-parts":[[2022,11,1]]},"published":{"date-parts":[[2022,11,1]]},"assertion":[{"value":"2022-03-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}