{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T07:54:33Z","timestamp":1782978873900,"version":"3.54.5"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T00:00:00Z","timestamp":1673049600000},"content-version":"vor","delay-in-days":67,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:00:00Z","timestamp":1659916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11,1]]},"abstract":"Summary<\/jats:title>Background<\/jats:title>There are no population-based epidemiological data on psoriasis in Southeast Asia, including Malaysia.<\/jats:p><\/jats:sec>Objectives<\/jats:title>To determine the incidence and prevalence of psoriasis over 11 years in multiethnic Johor Bahru, Malaysia.<\/jats:p><\/jats:sec>Methods<\/jats:title>A population-based cohort study was made using the Teleprimary Care database between January 2010 and December 2020. Cases of psoriasis, identified by ICD-10 diagnostic codes, were validated by dermatologists. Annual prevalence and incidence were estimated and stratified by age, sex and ethnicity.<\/jats:p><\/jats:sec>Results<\/jats:title>We identified 3932 people with dermatologist-confirmed psoriasis, including 1830 incident cases, among 1 164 724 Malaysians, yielding an 11-year prevalence of 0\u00b734% [95% confidence interval (CI) 0\u00b733\u20130\u00b735] and incidence of 34\u00b72 per 100 000 person-years (95% CI 32\u00b76\u201335\u00b78). Rates were higher in Indian patients; the prevalences were 0\u00b754% (0\u00b750\u20130\u00b758) in Indian, 0\u00b738% (0\u00b736\u20130\u00b740) in Chinese and 0\u00b729% (0\u00b728\u20130\u00b730) in Malay patients, and the respective incidences per 100 000 person-years were 52\u00b75 (47\u00b73\u201357\u00b77), 38\u00b70 (34\u00b71\u201341\u00b78) and 30\u00b70 (28\u00b72\u201331\u00b78). Rates were higher in males; the prevalence was 0\u00b739% (0\u00b737\u20130\u00b741) in males and 0\u00b729% (0\u00b727\u20130\u00b730) in females, and the respective incidences per 100 000 person-years were 40\u00b77 (38\u00b72\u201343\u00b72) and 28\u00b73 (26\u00b74\u201330\u00b73). Between 2010 and 2020, annual psoriasis prevalence and incidence increased steadily from 0\u00b727% to 0\u00b751% and from 27\u00b78 to 60\u00b79 per 100 000 person-years, respectively. Annual rates were consistently higher in male and Indian patients. Overall, psoriasis was significantly more common in males than females [odds ratio (OR) 1\u00b737, 95% CI 1\u00b729\u20131\u00b746] and in Indian and Chinese patients vs. Malay (OR 1\u00b785, 1\u00b771\u20132\u00b701 and OR 1\u00b730, 1\u00b720\u20131\u00b741, respectively). Prevalence increased with age, with the highest rates in the groups aged 50\u201359 and 60\u201369 years at 0\u00b767% and 0\u00b766%, respectively. A modest bimodal trend in age of psoriasis onset was observed, with first and second peaks at 20\u201329 and 50\u201359 years. Disease onset was significantly earlier in females than males [mean (SD) 36\u00b78 (17\u00b73) vs. 42\u00b70 (17\u00b72) years, P &lt; 0\u00b7001] and in Malay vs. Indian and Chinese patients [mean (SD): Malay 36\u00b74 (17\u00b75), Indian 40\u00b78 (15\u00b72), Chinese 47\u00b74 (16\u00b79) years, P &lt; 0\u00b7001].<\/jats:p><\/jats:sec>Conclusions<\/jats:title>We found that psoriasis incidence and prevalence are increasing and varied by age, sex and ethnicity. Our findings should help inform healthcare planning and management for patients with psoriasis in Malaysia.<\/jats:p>What is already known about this topic? \u00a0The incidence and prevalence of psoriasis are generally lower in Asian populations and children.There is a lack of agreement on sex-specific differences in psoriasis incidence and prevalence.There has been no population-based study on the incidence and prevalence of psoriasis in Southeast Asia, including Malaysia.There is no information on differences in psoriasis prevalence and incidence by sex, age and ethnicity in Malaysia.<\/jats:p>What does this study add? \u00a0Psoriasis incidence and prevalence are increasing in the multiethnic population of Johor Bahru, Malaysia.Incidence and prevalence rates were higher in male than female patients and were consistently highest among Indian patients, followed by Chinese and Malay.A modest bimodality in the age of psoriasis onset was observed among the groups aged 20\u201329 and 50\u201359 years.Psoriasis onset was significantly later in male than female patients and in Chinese vs. Indian and Malay patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/bjd.21768","type":"journal-article","created":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T15:59:25Z","timestamp":1657727965000},"page":"713-721","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Incidence and prevalence of psoriasis in multiethnic Johor Bahru, Malaysia: a population-based cohort study using electronic health data routinely captured in the Teleprimary Care (TPC\u00ae) clinical information system from 2010 to 2020"],"prefix":"10.1093","volume":"187","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7796-5746","authenticated-orcid":false,"given":"Siew Eng","family":"Choon","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital Sultanah Aminah Johor Bahru Johor Malaysia"},{"name":"Clinical School Johor Bahru, Jeffrey Cheah School of Medicine & Health Sciences Monash University Johor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison K.","family":"Wright","sequence":"additional","affiliation":[{"name":"Centre for Pharmacoepidemiology and Drug Safety, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health University of Manchester Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5371-4427","authenticated-orcid":false,"given":"Christopher E.M.","family":"Griffiths","sequence":"additional","affiliation":[{"name":"NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre University of Manchester Manchester UK"},{"name":"Dermatology Centre, Salford Royal NHS Foundation Trust, Manchester Academic Health Science Centre University of Manchester Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwee Eng","family":"Tey","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Sultanah Aminah Johor Bahru Johor Malaysia"},{"name":"Clinical School Johor Bahru, Jeffrey Cheah School of Medicine & Health Sciences Monash University Johor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kit Wan","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Sultanah Aminah Johor Bahru Johor Malaysia"},{"name":"Clinical School Johor Bahru, Jeffrey Cheah School of Medicine & Health Sciences Monash University Johor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoong Wei","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Sultanah Aminah Johor Bahru Johor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ushananthiny","family":"Suvelayutnan","sequence":"additional","affiliation":[{"name":"Department of Information and Communication Technology Hospital Sultanah Aminah Johor Bahru Johor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeevitha","family":"Mariapun","sequence":"additional","affiliation":[{"name":"Clinical School Johor Bahru, Jeffrey Cheah School of Medicine & Health Sciences Monash University Johor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren M.","family":"Ashcroft","sequence":"additional","affiliation":[{"name":"Centre for Pharmacoepidemiology and Drug Safety, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health University of Manchester Manchester UK"},{"name":"NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre University of Manchester Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Global Psoriasis 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