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Imaging is required for correct staging, in the follow\u2010up after treatment and, as recently highlighted, is predictor of prognosis. In the near future, whole\u2010body\n                    <jats:styled-content style=\"fixed-case\">X<\/jats:styled-content>\n                    \u2010Ray may be replaced by more sensitive techniques, such as whole\u2010body low\u2010dose computerized tomography (\n                    <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\n                    ). Magnetic resonance imaging (\n                    <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\n                    ) is the gold standard method for assessing bone marrow infiltration of the spine, predicting the risk of vertebral fracture and distinguishing between benign and malignant osteoporosis. Positron emission tomography (\n                    <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\n                    ) with\n                    <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\n                    (\n                    <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\n                    \/\n                    <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\n                    ) provides important information about the extent of whole\u2010body disease, including soft tissue masses, and is the best tool to distinguish between active or inactive disease after therapy. Both\n                    <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\n                    and\n                    <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\n                    \/\n                    <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\n                    are predictors of clinical outcome. A prospective use of these newer imaging techniques in both clinical trials and clinical practice may help optimize\n                    <jats:styled-content style=\"fixed-case\">MM<\/jats:styled-content>\n                    management in the near future.\n                  <\/jats:p>","DOI":"10.1111\/bjh.12007","type":"journal-article","created":{"date-parts":[[2012,8,11]],"date-time":"2012-08-11T03:35:25Z","timestamp":1344656125000},"page":"499-513","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":111,"title":["The role of imaging techniques in the management of multiple myeloma"],"prefix":"10.1111","volume":"159","author":[{"given":"Elena","family":"Zamagni","sequence":"first","affiliation":[{"name":"\u2018Ser\u00e0gnoli\u2019 Institute of Haematology Bologna University School of Medicine Bologna 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