{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:30:37Z","timestamp":1761489037226},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,11,15]],"date-time":"2012-11-15T00:00:00Z","timestamp":1352937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>We report the outcome of 92 non\u2010high risk children with acute lymphoblastic leukaemia (<jats:styled-content style=\"fixed-case\">ALL<\/jats:styled-content>) following a Berlin\u2010Frankf\u00fcrt\u2010M\u00fcnster (<jats:styled-content style=\"fixed-case\">BFM<\/jats:styled-content>) Intercontinental <jats:styled-content style=\"fixed-case\">ALL<\/jats:styled-content> \u2010based protocol. Compared with a matched historical control group, we found a lower incidence of treatment\u2010related early death (1\u00b72% vs. 10\u00b79%, <jats:italic>P\u00a0<\/jats:italic>=\u00a00\u00b7015), a higher 6\u2010year event\u2010free survival (75\u00b74\u00a0\u00b1\u00a04\u00b79% vs. 58\u00b72\u00a0\u00b1\u00a06\u00b77%, <jats:italic>P\u00a0<\/jats:italic>=\u00a00\u00b702), reduced total in\u2010hospital costs per person (<jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> $) (10267\u00b70 vs. 18331\u00b70, <jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00\u00b7001) and fewer total in\u2010hospital days (164 vs. 296, <jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00\u00b7001). This <jats:styled-content style=\"fixed-case\">ALL<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">BFM<\/jats:styled-content> based protocol was quite tolerable in our institution and will be extended to high\u2010risk patients.<\/jats:p>","DOI":"10.1111\/bjh.12122","type":"journal-article","created":{"date-parts":[[2012,11,15]],"date-time":"2012-11-15T18:49:06Z","timestamp":1353005346000},"page":"363-367","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Improved outcome for children with non\u2010high risk acute lymphoblastic leukaemia after using an <scp>ALL IC<\/scp>\u2010<scp>BFM<\/scp> 2002\u2010based protocol in Shanghai, China"],"prefix":"10.1111","volume":"160","author":[{"given":"Yi\u2010Jin","family":"Gao","sequence":"first","affiliation":[{"name":"Children's Hospital Shanghai Medical College Fudan University Shanghai 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