{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T03:53:03Z","timestamp":1774929183191,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":564,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2014,5]]},"DOI":"10.1111\/bjh.12775","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T07:15:25Z","timestamp":1392621325000},"page":"497-503","source":"Crossref","is-referenced-by-count":33,"title":["Arsenic trioxide during consolidation for patients with previously untreated low\/intermediate risk acute promyelocytic leukaemia may eliminate the need for maintenance therapy"],"prefix":"10.1111","volume":"165","author":[{"given":"Steven E.","family":"Coutre","sequence":"first","affiliation":[{"name":"Stanford University School of Medicine; Stanford CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Othus","sequence":"additional","affiliation":[{"name":"SWOG Statistical Center; Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bayard","family":"Powell","sequence":"additional","affiliation":[{"name":"Wake Forest University School of Medicine; Wake Forest NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheryl L.","family":"Willman","sequence":"additional","affiliation":[{"name":"University of New Mexico Cancer Center; Albuquerque NM USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy","family":"Stock","sequence":"additional","affiliation":[{"name":"University of Chicago; Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Paietta","sequence":"additional","affiliation":[{"name":"Montefiore Medical Center; North Division, Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise","family":"Levitan","sequence":"additional","affiliation":[{"name":"Wake Forest University School of Medicine; Wake Forest NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meir","family":"Wetzler","sequence":"additional","affiliation":[{"name":"Roswell Park Cancer Institute; Buffalo NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eyal C.","family":"Attar","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital; Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica K.","family":"Altman","sequence":"additional","affiliation":[{"name":"Northwestern University; Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven D.","family":"Gore","sequence":"additional","affiliation":[{"name":"Johns Hopkins University; Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy","family":"Maher","sequence":"additional","affiliation":[{"name":"SWOG Statistical Center; Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth J.","family":"Kopecky","sequence":"additional","affiliation":[{"name":"SWOG Statistical Center; Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin S.","family":"Tallman","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center; New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard A.","family":"Larson","sequence":"additional","affiliation":[{"name":"University of Chicago; Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederick R.","family":"Appelbaum","sequence":"additional","affiliation":[{"name":"Fred Hutchinson Cancer Research Center; Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,14]]},"reference":[{"key":"10.1111\/bjh.12775-BIB0001|bjh12775-cit-0001","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1182\/blood-2009-07-233387","article-title":"Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience","volume":"115","author":"Ades","year":"2010","journal-title":"Blood"},{"key":"10.1111\/bjh.12775-BIB0002|bjh12775-cit-0002","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1182\/blood-2006-08-043992","article-title":"A randomized study with or without intensified maintenance chemotherapy in patients with acute promyelocytic leukemia who have become negative for PML-RARalpha transcript after consolidation therapy: the Japan Adult Leukemia Study Group (JALSG) APL97 study","volume":"110","author":"Asou","year":"2007","journal-title":"Blood"},{"key":"10.1111\/bjh.12775-BIB0003|bjh12775-cit-0003","doi-asserted-by":"crossref","first-page":"4716","DOI":"10.1182\/blood-2010-08-302950","article-title":"AIDA 0493 protocol for newly diagnosed acute promyelocytic leukemia: very long-term results and role of maintenance","volume":"117","author":"Avvisati","year":"2011","journal-title":"Blood"},{"key":"10.1111\/bjh.12775-BIB0004|bjh12775-cit-0004","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1182\/blood.V94.4.1192","article-title":"A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. The European APL Group","volume":"94","author":"Fenaux","year":"1999","journal-title":"Blood"},{"key":"10.1111\/bjh.12775-BIB0005|bjh12775-cit-0005","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.leukres.2004.05.006","article-title":"Role of all-trans-retinoic acid (ATRA) in the consolidation therapy of acute promyelocytic leukaemia (APL)","volume":"29","author":"Gupta","year":"2005","journal-title":"Leukemia Research"},{"key":"10.1111\/bjh.12775-BIB0006|bjh12775-cit-0006","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1016\/j.leukres.2009.03.021","article-title":"The race and dose of chemotherapy should be considered for optimizing maintenance therapy for acute promyelocytic leukemia","volume":"33","author":"Nagai","year":"2009","journal-title":"Leukemia Research"},{"key":"10.1111\/bjh.12775-BIB0007|bjh12775-cit-0007","doi-asserted-by":"crossref","first-page":"3751","DOI":"10.1182\/blood-2010-02-269621","article-title":"Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710","volume":"116","author":"Powell","year":"2010","journal-title":"Blood"},{"key":"10.1111\/bjh.12775-BIB0008|bjh12775-cit-0008","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1182\/blood.V118.21.258.258","article-title":"Adding mercaptopurine and methotrexate to alternate week ATRA maintenance therapy does not improve the outcome for adults with acute promyelocytic leukemia (APL) in first remission: results from North American Leukemia Intergroup Trial C9710","volume":"118","author":"Powell","year":"2011","journal-title":"Blood"},{"key":"10.1111\/bjh.12775-BIB0009|bjh12775-cit-0009","volume-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2013"},{"key":"10.1111\/bjh.12775-BIB0010|bjh12775-cit-0010","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1200\/JCO.2010.32.1067","article-title":"Modern approaches to treating acute promyelocytic leukemia","volume":"29","author":"Sanz","year":"2011","journal-title":"Journal of Clinical Oncology"},{"key":"10.1111\/bjh.12775-BIB0011|bjh12775-cit-0011","first-page":"1247","article-title":"Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: a joint study of the PETHEMA and GIMEMA cooperative groups","volume":"96","author":"Sanz","year":"2000","journal-title":"Blood"},{"key":"10.1111\/bjh.12775-BIB0012|bjh12775-cit-0012","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1182\/blood-2003-07-2462","article-title":"Risk-adapted treatment of acute promyelocytic leukemia with all-trans-retinoic acid and anthracycline monochemotherapy: a multicenter study by the PETHEMA group","volume":"103","author":"Sanz","year":"2004","journal-title":"Blood"},{"key":"10.1111\/bjh.12775-BIB0013|bjh12775-cit-0013","doi-asserted-by":"crossref","first-page":"c332","DOI":"10.1136\/bmj.c332","article-title":"CONSORT 2010 Statement: updated guidelines for reporting parallel group randomized trials","volume":"340","author":"Schulz","year":"2010","journal-title":"BMJ"},{"key":"10.1111\/bjh.12775-BIB0014|bjh12775-cit-0014","doi-asserted-by":"crossref","first-page":"3395","DOI":"10.1182\/blood-2007-07-100669","article-title":"Causes and prognostic factors of remission induction failure in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and idarubicin","volume":"111","author":"Serna","year":"2008","journal-title":"Blood"},{"key":"10.1111\/bjh.12775-BIB0015|bjh12775-cit-0015","doi-asserted-by":"crossref","first-page":"5328","DOI":"10.1073\/pnas.0400053101","article-title":"All-trans retinoic acid\/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia","volume":"101","author":"Shen","year":"2004","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1111\/bjh.12775-BIB0016|bjh12775-cit-0016","doi-asserted-by":"crossref","first-page":"3852","DOI":"10.1200\/JCO.2001.19.18.3852","article-title":"United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia","volume":"19","author":"Soignet","year":"2001","journal-title":"Journal of Clinical Oncology"},{"key":"10.1111\/bjh.12775-BIB0017|bjh12775-cit-0017","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1056\/NEJM199710093371501","article-title":"All-trans-retinoic acid in acute promyelocytic leukemia","volume":"337","author":"Tallman","year":"1997","journal-title":"New England Journal of Medicine"},{"key":"10.1111\/bjh.12775-BIB0018|bjh12775-cit-0018","doi-asserted-by":"crossref","first-page":"2505","DOI":"10.1182\/blood-2007-07-102798","article-title":"Acute promyelocytic leukemia: from highly fatal to highly curable","volume":"111","author":"Wang","year":"2008","journal-title":"Blood"}],"container-title":["British Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbjh.12775","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/bjh.12775\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T08:24:35Z","timestamp":1625387075000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bjh.12775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,14]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,5]]}},"URL":"https:\/\/doi.org\/10.1111\/bjh.12775","relation":{},"ISSN":["0007-1048"],"issn-type":[{"value":"0007-1048","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2,14]]}}}