{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:46:56Z","timestamp":1788871616208,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T00:00:00Z","timestamp":1395705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P01-CA65493"],"award-info":[{"award-number":["P01-CA65493"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000885","name":"Children's Cancer Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000885","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2014,7]]},"abstract":"Summary<\/jats:title>\n \n Donor\u2010derived myelodysplastic syndrome\/acute leukaemia (\n DD<\/jats:styled-content>\n \u2010\n MDS<\/jats:styled-content>\n \/\n AL<\/jats:styled-content>\n ) is a rare life\u2010threatening complication of allogeneic haematopoietic stem cell (\n HSC<\/jats:styled-content>\n ) transplantation. However, it is unknown whether the risk differs by\n HSC<\/jats:styled-content>\n source. Therefore, we evaluated the incidence of\n DD<\/jats:styled-content>\n \u2010\n MDS<\/jats:styled-content>\n \/\n AL<\/jats:styled-content>\n in 2390 engrafted patients. With a median follow\u2010up of 7\u00b71\u00a0years (1\u201320\u00b78), the incidence of\n DD<\/jats:styled-content>\n \u2010\n MDS<\/jats:styled-content>\n \/\n AL<\/jats:styled-content>\n was 0\u00b753% (95% confidence interval (\n CI<\/jats:styled-content>\n ), 0\u00b701\u20131\u00b741%], 0\u00b756% (95%\n CI<\/jats:styled-content>\n , 0\u00b701\u20131\u00b736%) and 0\u00b756% (95%\n CI<\/jats:styled-content>\n , 0\u00b701\u20131\u00b710%) in recipients of bone marrow (\n n\u00a0<\/jats:italic>\n =\u00a01117), peripheral blood (\n n\u00a0<\/jats:italic>\n =\u00a0489) and umbilical cord blood (\n UCB<\/jats:styled-content>\n ,\n n\u00a0<\/jats:italic>\n =\u00a0784), respectively. While follow\u2010up is shorter in recipients of\n UCB<\/jats:styled-content>\n and peripheral blood, incidence of\n DD<\/jats:styled-content>\n \u2010\n MDS<\/jats:styled-content>\n \/\n AL<\/jats:styled-content>\n is, thus far, similar between\n HSC<\/jats:styled-content>\n sources.\n <\/jats:p>","DOI":"10.1111\/bjh.12847","type":"journal-article","created":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T03:57:13Z","timestamp":1395719833000},"page":"209-212","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Donor\u2010derived myelodysplastic syndrome and acute leukaemia after allogeneic haematopoietic stem cell transplantation: incidence, natural history and treatment response"],"prefix":"10.1111","volume":"166","author":[{"given":"Andrew C.","family":"Dietz","sequence":"first","affiliation":[{"name":"Division of Hematology Oncology, and Blood and Marrow Transplant Department of Pediatrics Rady Children's Hospital University of California San Diego San Diego CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd E.","family":"DeFor","sequence":"additional","affiliation":[{"name":"Blood and Marrow Transplant Program University of Minnesota Minneapolis MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio G.","family":"Brunstein","sequence":"additional","affiliation":[{"name":"Blood and Marrow Transplant Program University of Minnesota Minneapolis MN USA"},{"name":"Department of Medicine University of Minnesota Minneapolis MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"John E.","family":"Wagner","sequence":"additional","affiliation":[{"name":"Blood and Marrow Transplant Program University of Minnesota Minneapolis MN USA"},{"name":"Department of Pediatrics University of Minnesota Minneapolis MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,3,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(71)90998-6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-06-2551"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404293"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-09-309351"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2011.01584.x"},{"key":"e_1_2_7_7_1","first-page":"969","article-title":"Development of leukemia in donor cells after allogeneic stem cell transplantation\u2013a survey of the European Group for Blood and Marrow Transplantation (EBMT)","volume":"90","author":"Hertenstein 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