{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:54:17Z","timestamp":1791561257519,"version":"4.3.4"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,9,30]],"date-time":"2014-09-30T00:00:00Z","timestamp":1412035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>This study aimed to quantify the risks of <jats:italic>Pneumocystis<\/jats:italic> pneumonia (<jats:styled-content style=\"fixed-case\">PCP<\/jats:styled-content>) among adult T\u2010cell leukaemia (<jats:styled-content style=\"fixed-case\">ATL<\/jats:styled-content>) patients without prophylaxis. We used hospital administrative data collected nationwide in Japan over 4\u00a0years. The research design was a retrospective cohort study. Subjects were 4369 patients diagnosed with <jats:styled-content style=\"fixed-case\">ATL<\/jats:styled-content> aged 18\u00a0years or older. The subjects were categorized into four treatment groups: no agent, chemotherapy, chemotherapy\u00a0+\u00a0steroids and steroids. We described the risks of <jats:styled-content style=\"fixed-case\">PCP<\/jats:styled-content> among <jats:styled-content style=\"fixed-case\">ATL<\/jats:styled-content> patients without prophylaxis. Risks of <jats:styled-content style=\"fixed-case\">PCP<\/jats:styled-content> were 3\u00b72% for the no agent group, 9\u00b77% for the chemotherapy group, 10\u00b70% for the chemotherapy\u00a0+\u00a0steroids group and 16\u00b76% for the steroids group. Logistic regression analyses showed that the chemotherapy, chemotherapy\u00a0+\u00a0steroids and steroids groups had significantly higher risk of <jats:styled-content style=\"fixed-case\">PCP<\/jats:styled-content> than did the no agent group [adjusted odds ratio (<jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content>) 3\u00b730 (1\u00b755\u20137\u00b702), <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7002 for the chemotherapy group; <jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content> 3\u00b735 (2\u00b718\u20135\u00b717), <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b7001 for the chemotherapy\u00a0+\u00a0steroids group; <jats:styled-content style=\"fixed-case\">AOR<\/jats:styled-content> 6\u00b712 (3\u00b799\u20139\u00b738), <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b7001 for the steroids group]. In conclusion, the chemotherapy, chemotherapy\u00a0+\u00a0steroids and steroids groups had significantly higher risks of <jats:styled-content style=\"fixed-case\">PCP<\/jats:styled-content>. Prophylaxis for <jats:styled-content style=\"fixed-case\">PCP<\/jats:styled-content> among <jats:styled-content style=\"fixed-case\">ATL<\/jats:styled-content> patients being treated with chemotherapy, chemotherapy\u00a0+\u00a0steroids and steroids is highly recommended.<\/jats:p>","DOI":"10.1111\/bjh.13154","type":"journal-article","created":{"date-parts":[[2014,9,30]],"date-time":"2014-09-30T05:45:36Z","timestamp":1412055936000},"page":"501-506","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Quantification of the effect of chemotherapy and steroids on risk of <i><scp>P<\/scp>neumocystis jiroveci<\/i> among hospitalized patients with adult <scp>T<\/scp>\u2010cell leukaemia"],"prefix":"10.1111","volume":"168","author":[{"given":"Toshiki","family":"Maeda","sequence":"first","affiliation":[{"name":"Department of Healthcare Administration and Management Graduate School of Healthcare Sciences Kyushu University Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Babazono","sequence":"additional","affiliation":[{"name":"Department of Healthcare Administration and Management Graduate School of Healthcare Sciences Kyushu University Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takumi","family":"Nishi","sequence":"additional","affiliation":[{"name":"Department of Healthcare Administration and Management Graduate School of Healthcare Sciences Kyushu University Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Community Health University of Occupational and Environmental Health Fukukoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyohide","family":"Fushimi","sequence":"additional","affiliation":[{"name":"Department of Health Policy and Informatics Graduate School of Medicine Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Fujimori","sequence":"additional","affiliation":[{"name":"Department of Health Administration and Policy Tohoku University Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/334519a0"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.4065\/82.9.1052"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2007.01016.x"},{"key":"e_1_2_8_6_1","first-page":"1","article-title":"Guidelines for prevention and treatment of opportunistic infections in HIV\u2010infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV 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