{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T04:18:28Z","timestamp":1790050708088,"version":"4.0.1"},"reference-count":47,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,11,14]],"date-time":"2014-11-14T00:00:00Z","timestamp":1415923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Mature (peripheral) T\u2010cell lymphoma (\n                    <jats:styled-content style=\"fixed-case\">PTCL<\/jats:styled-content>\n                    ) other than anaplastic large cell lymphoma is a heterogeneous group of diseases and exceedingly rare in children and adolescents. Survival rates range between 46% and 85%. This study reports the disease characteristics, treatment and outcome of all patients with the diagnosis of mature\n                    <jats:styled-content style=\"fixed-case\">TCL<\/jats:styled-content>\n                    registered in the Berlin\u2010Frankfurt\u2010Munster non\u2010Hodgkin lymphoma database between 1986 and 2012. All diagnoses were centrally reviewed and revised by clinico\u2010pathological correlation according to the criteria of the current World Health Organization classification. Of the 69 patients originally registered as having\n                    <jats:styled-content style=\"fixed-case\">PTCL<\/jats:styled-content>\n                    , the diagnosis was confirmed in 38 of them. Most patients were treated with an anaplastic large cell lymphoma (\n                    <jats:styled-content style=\"fixed-case\">ALCL<\/jats:styled-content>\n                    )\u2010like therapy regimen. Patients with\n                    <jats:styled-content style=\"fixed-case\">PTCL<\/jats:styled-content>\n                    \u2010not otherwise specified comprised the largest group and showed a 5\u2010year event\u2010free survival rate of 61\u00a0\u00b1\u00a011%. Patients suffering from Natural Killer\/T\u2010cell\u2010 and hepatosplenic\n                    <jats:styled-content style=\"fixed-case\">TCL<\/jats:styled-content>\n                    had the poorest outcome. Our results suggest that the outcomes of children with mature\n                    <jats:styled-content style=\"fixed-case\">TCL<\/jats:styled-content>\n                    other than\n                    <jats:styled-content style=\"fixed-case\">ALCL<\/jats:styled-content>\n                    depend on the subtype and are worse than in all other paediatric lymphomas. The clinical experience presented in this largest study on paediatric mature\n                    <jats:styled-content style=\"fixed-case\">TCL<\/jats:styled-content>\n                    may serve as basis for future collaborative international prospective clinical trials.\n                  <\/jats:p>","DOI":"10.1111\/bjh.13216","type":"journal-article","created":{"date-parts":[[2014,11,14]],"date-time":"2014-11-14T00:26:27Z","timestamp":1415924787000},"page":"835-844","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Non\u2010anaplastic peripheral T\u2010cell lymphoma in children and adolescents \u2013 a retrospective analysis of the\n                    <scp>NHL<\/scp>\n                    \u2010\n                    <scp>BFM<\/scp>\n                    study group"],"prefix":"10.1111","volume":"168","author":[{"given":"Udo","family":"Kontny","sequence":"first","affiliation":[{"name":"Division of Paediatric Haematology, Oncology and Stem Cell Transplantation Department of Paediatrics and Adolescent Medicine University Medical Centre Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilske","family":"Oschlies","sequence":"additional","affiliation":[{"name":"Department of Pathology, Haematopathology Section and Lymph Node Registry University of Kiel Kiel Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willi","family":"Woessmann","sequence":"additional","affiliation":[{"name":"Department of Paediatric Haematology and Oncology NHL\u2010BFM\u2010Study Centre Justus Liebig University Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit","family":"Burkhardt","sequence":"additional","affiliation":[{"name":"Department of Paediatric Haematology and Oncology NHL\u2010BFM\u2010Study Centre University Children's Hospital M\u00fcnster 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