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Seventeen <jats:styled-content style=\"fixed-case\">CHL<\/jats:styled-content> cases were tested and lymphoma\u2010specific sequences were identified in 12 of the primary tumour biopsies. In 11 of these patients whose paired <jats:styled-content style=\"fixed-case\">PB<\/jats:styled-content> samples were available, tumour\u2010specific clonotypes were detected in <jats:styled-content style=\"fixed-case\">PB<\/jats:styled-content> in eight patients. This data demonstrates the feasibility of detecting circulating tumour\u2010specific sequences, creating an unprecedented opportunity to optimize the future treatment and monitoring strategies for patients with <jats:styled-content style=\"fixed-case\">CHL<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/bjh.13349","type":"journal-article","created":{"date-parts":[[2015,3,30]],"date-time":"2015-03-30T03:14:59Z","timestamp":1427685299000},"page":"689-693","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Detection of classical Hodgkin lymphoma specific sequence in peripheral blood using a next\u2010generation sequencing approach"],"prefix":"10.1111","volume":"169","author":[{"given":"Yasuhiro","family":"Oki","sequence":"first","affiliation":[{"name":"Department of Lymphoma and Myeloma The University of Texas M.D. Anderson Cancer Center Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sattva S.","family":"Neelapu","sequence":"additional","affiliation":[{"name":"Department of Lymphoma and Myeloma The University of Texas M.D. Anderson Cancer Center Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Fanale","sequence":"additional","affiliation":[{"name":"Department of Lymphoma and Myeloma The University of Texas M.D. Anderson Cancer Center Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry W.","family":"Kwak","sequence":"additional","affiliation":[{"name":"Department of Lymphoma and Myeloma The University of Texas M.D. Anderson Cancer Center Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Fayad","sequence":"additional","affiliation":[{"name":"Department of Lymphoma and Myeloma The University of Texas M.D. Anderson Cancer Center Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria A.","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Lymphoma and Myeloma The University of Texas M.D. Anderson Cancer Center Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Wallace","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology The University of Texas M.D. Anderson Cancer Center Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Klinger","sequence":"additional","affiliation":[{"name":"Sequenta, Inc. 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