{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T10:47:45Z","timestamp":1768992465390,"version":"3.49.0"},"reference-count":50,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,12,18]],"date-time":"2015-12-18T00:00:00Z","timestamp":1450396800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2016,3]]},"abstract":"Summary<\/jats:title>Comparative data regarding the distribution of non\u2010Hodgkin lymphoma (NHL<\/jats:styled-content>) subtypes in North Africa, the Middle East and India (NAF<\/jats:styled-content>\/ME<\/jats:styled-content>\/IN<\/jats:styled-content>) is scarce in the literature. In this study, we evaluated the relative frequencies of NHL<\/jats:styled-content> subtypes in this region. Five expert haematopathologists classified 971 consecutive cases of newly\u2010diagnosed NHL<\/jats:styled-content> from five countries in NAF<\/jats:styled-content>\/ME<\/jats:styled-content>\/IN<\/jats:styled-content>. After review, 890 cases (91\u00b77%) were confirmed to be NHL<\/jats:styled-content> and compared to 399 cases from North America (NA<\/jats:styled-content>). The male\u2010to\u2010female ratio was significantly higher in NAF<\/jats:styled-content>\/ME<\/jats:styled-content>\/IN<\/jats:styled-content> (1\u00b78) compared to NA<\/jats:styled-content> (1\u00b71; P<\/jats:italic><\u00a00\u00b705). The median ages of patients with low\u2010grade (LG<\/jats:styled-content>) and high\u2010grade (HG<\/jats:styled-content>) B\u2010NHL<\/jats:styled-content> in NAF<\/jats:styled-content>\/ME<\/jats:styled-content>\/IN<\/jats:styled-content> (56 and 52\u00a0years, respectively) were significantly lower than in NA<\/jats:styled-content> (64 and 68\u00a0years, respectively). In NAF<\/jats:styled-content>\/ME<\/jats:styled-content>\/IN<\/jats:styled-content>, a significantly lower proportion of LG<\/jats:styled-content> B\u2010NHL<\/jats:styled-content> (28\u00b74%) and a higher proportion of HG<\/jats:styled-content> B\u2010NHL<\/jats:styled-content> (58\u00b74%) were found compared to NA<\/jats:styled-content> (56\u00b71% and 34\u00b73%, respectively). Diffuse large B\u2010cell lymphoma was more common in NAF<\/jats:styled-content>\/ME<\/jats:styled-content>\/IN<\/jats:styled-content> (49\u00b74%) compared to NA<\/jats:styled-content> (29\u00b73%), whereas follicular lymphoma was less common in NAF<\/jats:styled-content>\/ME<\/jats:styled-content>\/IN<\/jats:styled-content> (12\u00b74%) than in NA<\/jats:styled-content> (33\u00b76%). In conclusion, we found significant differences in NHL<\/jats:styled-content> subtypes and clinical features between NAF<\/jats:styled-content>\/ME<\/jats:styled-content>\/IN<\/jats:styled-content> and NA<\/jats:styled-content>. Epidemiological studies are needed to better understand the pathobiology of these differences.<\/jats:p>","DOI":"10.1111\/bjh.13876","type":"journal-article","created":{"date-parts":[[2015,12,19]],"date-time":"2015-12-19T01:10:36Z","timestamp":1450487436000},"page":"699-708","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Relative frequency of non\u2010Hodgkin lymphoma subtypes in selected centres in North Africa, the middle east and India: a review of 971 cases"],"prefix":"10.1111","volume":"172","author":[{"given":"Anamarija M.","family":"Perry","sequence":"first","affiliation":[{"name":"Department of Pathology University of Manitoba Winnipeg MB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Diebold","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology and Cytology Hotel\u2010Dieu, University Denis Diderot Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bharat N.","family":"Nathwani","sequence":"additional","affiliation":[{"name":"Department of Pathology City of Hope National Medical Center Duarte CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth A.","family":"MacLennan","sequence":"additional","affiliation":[{"name":"Section\u00a0of Pathology and Leeds Institute of Molecular Medicine St. James University Hospital West Yorkshire UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans K.","family":"M\u00fcller\u2010Hermelink","sequence":"additional","affiliation":[{"name":"Institute of Pathology University of W\u00fcrzburg W\u00fcrzburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Bast","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Nebraska Medical Center Omaha NE USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene","family":"Boilesen","sequence":"additional","affiliation":[{"name":"Center for Collaboration on Research, Design and Analysis College of Public Health University of Nebraska Medical Center Omaha NE USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James O.","family":"Armitage","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Nebraska Medical Center Omaha NE USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis D.","family":"Weisenburger","sequence":"additional","affiliation":[{"name":"Department of Pathology City of Hope National Medical Center Duarte CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.cej.0000243858.91642.c9"},{"key":"e_1_2_6_3_1","first-page":"677","article-title":"Malignant lymphoma in Al\u2010Qassim, Saudi Arabia, reclassified according to the WHO classification","volume":"30","author":"Akhtar S.S.","year":"2009","journal-title":"Saudi Medical Journal"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22719"},{"key":"e_1_2_6_5_1","first-page":"609","article-title":"Non\u2010Hodgkin lymphoma in Jordan. 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