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The adolescent and young adult (<jats:styled-content style=\"fixed-case\">AYA<\/jats:styled-content>) population presents a specific set of characteristics and challenges. The most common diseases occurring in adolescents and young adults include Burkitt lymphoma, lymphoblastic lymphoma, diffuse large B\u2010cell lymphoma, anaplastic large cell lymphoma and primary mediastinal B\u2010cell lymphoma. There is also a higher incidence of primary central nervous system lymphoma in <jats:styled-content style=\"fixed-case\">AYA<\/jats:styled-content> patients. Cure rates largely depend on risk\u2010stratification, and are generally superior to outcomes in comparison to older adult data but less than in younger children. Here, we review the unique clinical and biological characteristics of <jats:styled-content style=\"fixed-case\">NHL<\/jats:styled-content> occurring in the <jats:styled-content style=\"fixed-case\">AYA<\/jats:styled-content> population with a focus on how to achieve similar curative outcomes in <jats:styled-content style=\"fixed-case\">AYA<\/jats:styled-content> that have been established in younger cohorts.<\/jats:p>","DOI":"10.1111\/bjh.14074","type":"journal-article","created":{"date-parts":[[2016,4,13]],"date-time":"2016-04-13T06:51:34Z","timestamp":1460530294000},"page":"637-650","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Adolescent and young adult non\u2010Hodgkin lymphoma"],"prefix":"10.1111","volume":"173","author":[{"given":"Jessica","family":"Hochberg","sequence":"first","affiliation":[{"name":"Department of Pediatrics New York Medical College Valhalla NY 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