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Stage <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content> disease has had poor outcomes. In an attempt to improve the outcome for higher stage disease, anthracyclines were added to the existing protocol. The disease\u2010free (<jats:styled-content style=\"fixed-case\">DFS<\/jats:styled-content>) and overall survival (<jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content>) of 58 children with cytologically confirmed Burkitt lymphoma admitted during 2012\u20132014 and treated using this protocol were calculated. Six (10%) children had stage I disease, ten (17%) stage <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> and 42 stage <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content> (73%). Overall 12\u2010month <jats:styled-content style=\"fixed-case\">DFS<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content>) was 68\u00b75% (72\u00b79%); for stage I disease 100% (100%), stage <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> 56\u00b72% (60%), stage <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content> 66\u00b73% (72\u00b72%). The <jats:styled-content style=\"fixed-case\">DFS<\/jats:styled-content> was significantly improved from the previous protocol (<jats:italic>P<\/jats:italic>\u00a0=\u00a08\u00a0\u00d7\u00a010<jats:sup>\u22124<\/jats:sup>). The addition of doxorubicin to stage <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content> disease resulted in a markedly improved <jats:styled-content style=\"fixed-case\">DFS<\/jats:styled-content>. Anthracyclines are deliverable in resource\u2010poor settings and possibly improve the survival of children with Burkitt lymphoma.<\/jats:p>","DOI":"10.1111\/bjh.14440","type":"journal-article","created":{"date-parts":[[2016,11,28]],"date-time":"2016-11-28T07:03:02Z","timestamp":1480316582000},"page":"984-990","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["The use of anthracyclines in the treatment of endemic Burkitt lymphoma"],"prefix":"10.1111","volume":"177","author":[{"given":"Elizabeth","family":"Molyneux","sequence":"first","affiliation":[{"name":"Department of Paediatrics Queen Elizabeth Central Hospital and College of Medicine Blantyre Malawi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ed","family":"Schwalbe","sequence":"additional","affiliation":[{"name":"Department of Applied Sciences University of Northumbria Newcastle upon Tyne 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