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It is thus important to recognise the cumulative burden of the disease and treatment\u2010related toxicity in both the stable and active phases of myeloma, some of which is unlikely to be detected by routine monitoring. We summarise here the evidence for the key late effects in long\u2010term survivors of myeloma, including physical and psychosocial consequences (in Parts 1 and 2 respectively), and recommend the use of late\u2010effects screening protocols in detection and intervention. 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