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Once classically described as an acute hepatitis associated with waterborne outbreaks in areas of poor sanitation, <jats:styled-content style=\"fixed-case\">HEV<\/jats:styled-content> is now recognised to be endemic in Europe and is probably zoonotic in origin. Evidence for transfusion\u2010transmitted <jats:styled-content style=\"fixed-case\">HEV<\/jats:styled-content> has prompted the introduction of blood donor screening in a number of countries, but the risk to the haematology patient from food sources remains. The aim of this review therefore, is to equip the clinical haematologist with the knowledge required to diagnose <jats:styled-content style=\"fixed-case\">HEV<\/jats:styled-content> infection and to aid decision\u2010making in patient management. 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