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Hodgkin lymphoma (<jats:styled-content style=\"fixed-case\">HL<\/jats:styled-content>) mostly affects young adults. Data regarding <jats:styled-content style=\"fixed-case\">CRCI<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">HL<\/jats:styled-content> survivors (<jats:styled-content style=\"fixed-case\">HLS<\/jats:styled-content>) are scarce. The current study aimed to objectively assess <jats:styled-content style=\"fixed-case\">CRCI<\/jats:styled-content> incidence and characteristics in <jats:styled-content style=\"fixed-case\">HLS<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">HLS<\/jats:styled-content>, who completed first\u2010line (chemotherapy\u00a0\u00b1\u00a0radiation) therapy and remained in complete remission for 6\u00a0months to 5\u00a0years from therapy end, were evaluated. Age\u2010 and education\u2010matched healthy individuals served as controls (<jats:italic>n<\/jats:italic>\u00a0=\u00a014). Test results were compared to population norms and healthy controls. Study participants completed self\u2010reported questionnaires evaluating fatigue, depression, anxiety, quality of life and cognitive function. Subjects underwent neurocognitive evaluation, assessing processing speed, memory, attention, executive functions and intelligence domains. The present study included 51 <jats:styled-content style=\"fixed-case\">HLS<\/jats:styled-content> with a median age of 28\u00a0years, mean education of 14\u00b75\u00a0\u00b1\u00a02\u00b75\u00a0years. Complaints related to cognitive deterioration and fatigue were significantly more severe and frequent in <jats:styled-content style=\"fixed-case\">HLS<\/jats:styled-content> compared to healthy controls. Objective neurocognitive evaluation demonstrated that 30% of <jats:styled-content style=\"fixed-case\">HLS<\/jats:styled-content> were impaired in \u22652 cognitive domains. In conclusion, the present study demonstrates that fatigue and cognitive impairment, predominantly in executive functions and memory, constitute frequent and alarming findings in <jats:styled-content style=\"fixed-case\">HLS<\/jats:styled-content>. 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