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The quality of response at transplantation is the most relevant prognostic aspect, as patients in complete response can obtain better outcomes. Therefore, first\u2010line salvage treatments applied before transplantation need to produce high quality responses without excessive myelotoxicity and without affecting peripheral blood stem cell mobilisation. In this sense, the incorporation of new agents active in Hodgkin lymphoma, such as brentuximab vedotin and anti\u2010programmed\u00a0death 1 antibodies, in conventional regimens, may help to enhance complete remission rates. Working on conditioning regimen and applying a post\u2010autologous consolidation treatment (for example with brentuximab vedotin) are two ways for improving transplant outcomes, particularly in patients displaying high\u2010risk features for early relapse or progression. Allogeneic transplantation maintains its curative potential also in the era of new drugs, although its most correct timing and the most suitable sequence of post\u2010autologous\u00a0salvage treatments still remain to be determined.<\/jats:p>","DOI":"10.1111\/bjh.15639","type":"journal-article","created":{"date-parts":[[2018,11,8]],"date-time":"2018-11-08T16:15:03Z","timestamp":1541693703000},"page":"93-104","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["The role of transplantation in Hodgkin lymphoma"],"prefix":"10.1111","volume":"184","author":[{"given":"Alessandro","family":"Broccoli","sequence":"first","affiliation":[{"name":"Institute of Haematology \u201cL. e A. 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