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There are limited data focusing on host characteristics and their effect on survival among multiple myeloma (<jats:styled-content style=\"fixed-case\">MM<\/jats:styled-content>) patients and individuals with monoclonal gammopathy of undetermined significance (<jats:styled-content style=\"fixed-case\">MGUS<\/jats:styled-content>). Therefore, our aim was to evaluate the impact of parental longevity on survival of patients with <jats:styled-content style=\"fixed-case\">MM<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MGUS<\/jats:styled-content>. A total of 4675 patients with <jats:styled-content style=\"fixed-case\">MM<\/jats:styled-content>, 6812 <jats:styled-content style=\"fixed-case\">MGUS<\/jats:styled-content> patients and 13\u00a0398 population\u2010based controls for <jats:styled-content style=\"fixed-case\">MM<\/jats:styled-content> as well as 19\u00a0110 controls for <jats:styled-content style=\"fixed-case\">MGUS<\/jats:styled-content>, from 1988 to 2013, were included in the study. Longevity was defined as &gt;90\u00a0years of age. Among <jats:styled-content style=\"fixed-case\">MM<\/jats:styled-content> patients, parental longevity was associated with a decreased risk of death [hazard ratio (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>)\u00a0=\u00a00\u00b792, 95% confidence interval (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) 0\u00b784\u20130\u00b799] and the same was true for <jats:styled-content style=\"fixed-case\">MGUS<\/jats:styled-content> patients (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u00a0=\u00a00\u00b787, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0\u00b778\u20130\u00b796). Having one long lived parent significantly decreased the risk of death in both groups, but was not statistically significant when both parents exceeded 90\u00a0years of age. In conclusion, parental longevity decreases the risk of death for patients with <jats:styled-content style=\"fixed-case\">MM<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MGUS<\/jats:styled-content> which may reflect the importance of the host's genetic and environmental factors in relation to survival.<\/jats:p>","DOI":"10.1111\/bjh.15883","type":"journal-article","created":{"date-parts":[[2019,3,25]],"date-time":"2019-03-25T02:53:10Z","timestamp":1553482390000},"page":"37-44","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Parental longevity and survival among patients with multiple myeloma and monoclonal gammopathy of undetermined significance: a population\u2010based study"],"prefix":"10.1111","volume":"186","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2353-573X","authenticated-orcid":false,"given":"Ingiger\u00f0ur 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