{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T04:47:26Z","timestamp":1789015646416,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,11,4]],"date-time":"2019-11-04T00:00:00Z","timestamp":1572825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004720","name":"NCR","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004720","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>In this nationwide, population\u2010based study, we assessed trends in primary treatment and survival among 687 patients with nodular lymphocyte\u2010predominant Hodgkin lymphoma (75% males; median age, 40\u00a0years; and 74% stage\u2010I\/II disease) diagnosed in the Netherlands between 1993\u20132016. There were no noteworthy changes in the application of primary therapy over time among adult patients across the different disease stages and age groups. Survival among various subgroups of adult patients was largely comparable to the expected survival of the general population. A particularly encouraging finding was that young adult patients experienced virtually no excess mortality, as compared to the general population.<\/jats:p>","DOI":"10.1111\/bjh.16290","type":"journal-article","created":{"date-parts":[[2019,11,4]],"date-time":"2019-11-04T12:44:49Z","timestamp":1572871489000},"page":"117-121","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Primary therapy and survival among patients with nodular lymphocyte\u2010predominant Hodgkin lymphoma: a population\u2010based analysis in the Netherlands, 1993\u20132016"],"prefix":"10.1111","volume":"189","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8162-5982","authenticated-orcid":false,"given":"Hidde L. A.","family":"Posthuma","sequence":"first","affiliation":[{"name":"Department of Haematology Cancer Center Amsterdam Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9e M.","family":"Zijlstra","sequence":"additional","affiliation":[{"name":"Department of Haematology Cancer Center Amsterdam Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otto","family":"Visser","sequence":"additional","affiliation":[{"name":"Department of Registration Netherlands Comprehensive Cancer Organisation (IKNL) Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6735-8651","authenticated-orcid":false,"given":"Pieternella J.","family":"Lugtenburg","sequence":"additional","affiliation":[{"name":"Department of Haematology Erasmus MC Cancer Institute Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Jos\u00e9","family":"Kersten","sequence":"additional","affiliation":[{"name":"Department of Haematology Cancer Center Amsterdam Amsterdam UMC University of Amsterdam Amsterdam The Netherlands"},{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE) Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4767-6716","authenticated-orcid":false,"given":"Avinash G.","family":"Dinmohamed","sequence":"additional","affiliation":[{"name":"Department of Haematology Cancer Center Amsterdam Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands"},{"name":"Department of Haematology Cancer Center Amsterdam Amsterdam UMC University of Amsterdam Amsterdam The Netherlands"},{"name":"Department of Research Netherlands Comprehensive Cancer Organisation (IKNL) Utrecht The Netherlands"},{"name":"Department of Public Health Erasmus University Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1383"},{"key":"e_1_2_8_3_1","first-page":"1889","article-title":"European task force on Lymphoma project on lymphocyte predominance Hodgkin disease: histologic and immunohistologic analysis of submitted cases reveals 2 types of Hodgkin disease with a nodular growth pattern and abundant lymphocytes","volume":"96","author":"Anagnostopoulos I.","year":"2000","journal-title":"Blood"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-10-877761"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.24.0945"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2006.01677.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1597"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2017011031"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-12-820381"},{"key":"e_1_2_8_10_1","unstructured":"Ederer F.&Heise H.(1959)Instructions to IBM 650 Programmers in Processing Survival Computations Methodological Note No. 10. 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