{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T04:58:18Z","timestamp":1789016298575,"version":"build-2803163510"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T00:00:00Z","timestamp":1580688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Patients with mantle cell lymphoma progressing on Bruton\u2019s tyrosine kinase inhibitor (BTKi) have very poor prognosis and there is currently no standard of care. In this retrospective cohort study, patients progressing on BTKi received R\u2010BAC (rituximab, bendamustine, cytarabine). Overall response rate was 83% (complete response 60%) and 31% were bridged to allogeneic stem cell transplant (alloSCT). Median progression\u2010free survival was 10.1 months (95% confidence interval (CI) 6\u00b79\u201313\u00b73) and median overall survival was 12\u00b75 months (95% CI 11\u00b70\u201314\u00b70). In those consolidated with alloSCT only one patient relapsed. R\u2010BAC demonstrates a high response rate in the post\u2010BTKi setting and in transplant eligible patients is an effective bridge to alloSCT.<\/jats:p>","DOI":"10.1111\/bjh.16416","type":"journal-article","created":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T10:56:11Z","timestamp":1580727371000},"page":"684-688","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Efficacy of R\u2010BAC in relapsed, refractory mantle cell lymphoma post BTK inhibitor therapy"],"prefix":"10.1111","volume":"189","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0090-7174","authenticated-orcid":false,"given":"Rory","family":"McCulloch","sequence":"first","affiliation":[{"name":"Department of Haematology University Hospitals Plymouth NHS Trust Plymouth 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