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We identified causes of death amongst 7289 adults diagnosed with incident first primary LPL (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a03108) or WM (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a04181) during 2000\u20132016 in 17 USA population\u2010based cancer registries. Based on 3132 deaths, 16\u2010year cumulative mortality was 23\u00b72% for lymphomas, 8\u00b74% for non\u2010lymphoma cancers and 14\u00b77% for non\u2010cancer causes for patients aged &lt;65\u00a0years at diagnosis of LPL\/WM,\n                    <jats:italic>versus<\/jats:italic>\n                    33\u00b74%, 11\u00b72% and 48\u00b77%, respectively, for those aged \u226575\u00a0years. Compared with the general population, patients with LPL\/WM had a 20% higher risk of death due to non\u2010cancer causes (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a01341 deaths, standardised mortality ratio [SMR] 1\u00b72, 95% confidence interval [CI] 1\u00b71\u20131\u00b72), most commonly from infectious (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0188; SMR 1\u00b78, 95% CI 1\u00b76\u20132\u00b71), respiratory (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0143; SMR 1\u00b72, 95% CI 1\u00b70\u20131\u00b74), and digestive (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a080; SMR 1\u00b78, 95% CI 1\u00b74\u20132\u00b72) diseases, but no excess mortality from cardiovascular diseases (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0477, SMR 1\u00b71, 95% CI 1\u00b70\u20131\u00b71). Risks were highest for non\u2010cancer causes within 1\u00a0year of diagnosis (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0239; SMR\n                    <jats:sub>&lt;1year<\/jats:sub>\n                    1\u00b73, 95% CI 1\u00b72\u20131\u00b75), declining thereafter (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0522; SMR\n                    <jats:sub>\u22655years<\/jats:sub>\n                    1\u00b71, 95% CI 1\u00b71\u20131\u00b72). Myelodysplastic syndrome\/acute myeloid leukaemia deaths were notably increased (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a046; SMR 4\u00b74, 95% CI 3\u00b72\u20135\u00b79), whereas solid neoplasm deaths were only elevated among \u22655\u2010year survivors (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0145; SMR\n                    <jats:sub>\u22655years<\/jats:sub>\n                    1\u00b73, 95% CI 1\u00b71\u20131\u00b75). This work identifies new areas for optimising care and reducing mortality for patients with LPL\/WM.\n                  <\/jats:p>","DOI":"10.1111\/bjh.16492","type":"journal-article","created":{"date-parts":[[2020,2,23]],"date-time":"2020-02-23T21:46:35Z","timestamp":1582494395000},"page":"1107-1118","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Cause\u2010specific mortality in individuals with lymphoplasmacytic lymphoma\/Waldenstr\u00f6m macroglobulinaemia, 2000\u20132016"],"prefix":"10.1111","volume":"189","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0627-3603","authenticated-orcid":false,"given":"Nicole H.","family":"Dalal","sequence":"first","affiliation":[{"name":"Department of Health and Human Services National Institutes of Health National Cancer Institute Division of Cancer Epidemiology and Genetics Bethesda MD USA"},{"name":"Duke University School of Medicine Durham NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3985-2935","authenticated-orcid":false,"given":"Gra\u00e7a M.","family":"Dores","sequence":"additional","affiliation":[{"name":"Department of Health and Human Services National Institutes of Health National Cancer Institute Division of Cancer Epidemiology and Genetics Bethesda MD USA"},{"name":"United States Food and Drug Administration Center for Biologics Evaluation and Research Silver Spring MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rochelle E.","family":"Curtis","sequence":"additional","affiliation":[{"name":"Department of Health and Human Services National Institutes of Health National Cancer Institute Division of Cancer Epidemiology and Genetics Bethesda MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1687-5587","authenticated-orcid":false,"given":"Martha S.","family":"Linet","sequence":"additional","affiliation":[{"name":"Department of Health and Human Services National Institutes of Health National Cancer Institute Division of Cancer Epidemiology and Genetics Bethesda MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9767-2310","authenticated-orcid":false,"given":"Lindsay M.","family":"Morton","sequence":"additional","affiliation":[{"name":"Department of Health and Human Services National Institutes of Health National Cancer Institute Division of Cancer Epidemiology and Genetics Bethesda MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hon.2607"},{"key":"e_1_2_8_3_1","volume-title":"Statistical methods in cancer research. 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