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We compared mid\u2010treatment interim TARC (iTARC) with interim <jats:sup>18<\/jats:sup>F\u2010fluorodeoxyglucose positron\u2010emission tomography (iPET) imaging to predict modified progression\u2010free survival (mPFS) in a group of 95 patients with cHL. High iTARC levels were found in nine and positive iPET in 17 patients. The positive predictive value (PPV) of iTARC for a 5\u2010year mPFS event was 88% compared to 47% for iPET. The negative predictive value was comparable at 86% for iTARC and 85% for iPET. Serum iTARC levels more accurately reflect treatment response with a higher PPV compared to iPET.<\/jats:p>","DOI":"10.1111\/bjh.16514","type":"journal-article","created":{"date-parts":[[2020,2,27]],"date-time":"2020-02-27T23:56:01Z","timestamp":1582847761000},"page":"40-44","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Interim thymus and activation regulated chemokine <i>versus<\/i> interim <sup>18<\/sup>F\u2010fluorodeoxyglucose positron\u2010emission tomography in classical Hodgkin lymphoma response evaluation"],"prefix":"10.1111","volume":"190","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9828-9460","authenticated-orcid":false,"given":"Wouter J.","family":"Plattel","sequence":"first","affiliation":[{"name":"Department of Hematology University Medical Center Groningen University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia","family":"Visser","sequence":"additional","affiliation":[{"name":"Department of Pathology and Medical Biology University Medical Center Groningen  University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjan","family":"Diepstra","sequence":"additional","affiliation":[{"name":"Department of Pathology and Medical Biology University Medical Center Groningen  University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andor W. 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