{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T04:57:03Z","timestamp":1790139423856,"version":"4.0.1"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T00:00:00Z","timestamp":1582156800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Little is known about the incidence of late effects following non\u2010Hodgkin lymphoma (NHL) among adolescent and young adult (AYA, 15\u201339\u00a0years) survivors. Using data from the California Cancer Registry linked to hospital discharge, we estimated the cumulative incidence of late effects at 10\u00a0years among AYAs diagnosed with NHL during 1996\u20132012, who survived \u22652\u00a0years. Cox proportional\u2010hazards models were used to investigate the influence of sociodemographic and clinical factors on the occurrence of late effects. Of 4392 HIV\u2010uninfected patients, the highest incident diseases were: endocrine (18\u00b75%), cardiovascular (11\u00b77%), and respiratory (5\u00b70%), followed by secondary primary malignancy (SPM, 2\u00b76%), renal and neurologic (2\u00b72%), liver\/pancreatic (2\u00b70%), and avascular necrosis (1\u00b72%). Among the 425 HIV\u2010infected survivors, incidence was higher for all late effects, especially over threefold increased risk of SPM, compared to HIV\u2010uninfected patients (8\u00b71% vs. 2\u00b76%). In multivariable models for HIV\u2010uninfected patients, public or no health insurance (vs. private), residence in lower socioeconomic neighbourhoods (vs. higher), and receipt of a haematopoietic stem cell transplant were associated with a greater risk of most late effects. Our findings of substantial incidence of late effects among NHL AYA survivors emphasise the need for longterm follow\u2010up and appropriate survivorship care to reduce morbidity and mortality in this vulnerable population.<\/jats:p>","DOI":"10.1111\/bjh.16539","type":"journal-article","created":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T05:41:27Z","timestamp":1582263687000},"page":"371-384","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Chronic medical conditions and late effects following non\u2010Hodgkin lymphoma in HIV\u2010uninfected and HIV\u2010infected adolescents and young adults: a population\u2010based study"],"prefix":"10.1111","volume":"190","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1644-0313","authenticated-orcid":false,"given":"Renata","family":"Abrah\u00e3o","sequence":"first","affiliation":[{"name":"Center for Oncology Hematology Outcomes Research and Training (COHORT) Division of Hematology and Oncology University of California, Davis, School of Medicine Sacramento CA USA"},{"name":"Center for Healthcare Policy and Research University of California, Davis, School of Medicine Sacramento CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian W.","family":"Li","sequence":"additional","affiliation":[{"name":"Center for Oncology Hematology Outcomes Research and Training (COHORT) Division of Hematology and Oncology University of California, Davis, School of Medicine Sacramento CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcio H.","family":"Malogolowkin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Hematology and Oncology University of California, Davis, School of Medicine Sacramento CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elysia M.","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Center for Oncology Hematology Outcomes Research and Training (COHORT) Division of Hematology and Oncology University of California, Davis, School of Medicine Sacramento CA USA"},{"name":"Department of Pediatrics Division of Hematology and Oncology University of California, Davis, School of Medicine Sacramento CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul C.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Department of Oncology Division of Hematology and Oncology St. Jude Children's Research Hospital Memphis TN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ted","family":"Wun","sequence":"additional","affiliation":[{"name":"Center for Oncology Hematology Outcomes Research and Training (COHORT) Division of Hematology and Oncology University of California, Davis, School of Medicine Sacramento CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1961-4008","authenticated-orcid":false,"given":"Theresa H. 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