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The TARGET survey examined real\u2010world management of CML patients compared with international recommendations. This online survey was completed in 2017. Results were discussed by a Steering Committee (SC) of eight international haematologists, challenges were identified and practical solutions developed. Of the 1008 haematologists invited (33 countries), 614 completed the survey. Gaps regarding treatment efficacy and molecular monitoring were identified. Half of the physicians did not perform three\u2010monthly testing of during the initial 12\u00a0months of treatment, citing cost as the major barrier, although they know it should be done. Treatment\u2010free remission was not considered a primary treatment goal or as a priority factor influencing treatment decisions. European Leukemia Net guidelines interpretation was generally acceptable, but awareness regarding management of persistent adverse events was poor. Practical solutions proposed by the SC were mostly focused on enhancing physician education and awareness, or encouraging hospitals to work with the government, in order to improve the quality of BCR\u2010ABL testing. Gaps in current CML management were identified compared with international recommendations, which the proposed practical solutions would help to address.<\/jats:p>","DOI":"10.1111\/bjh.16599","type":"journal-article","created":{"date-parts":[[2020,3,30]],"date-time":"2020-03-30T19:34:05Z","timestamp":1585596845000},"page":"869-876","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["TARGET: a survey of real\u2010world management of chronic myeloid leukaemia across 33 countries"],"prefix":"10.1111","volume":"190","author":[{"given":"Anna","family":"Turkina","sequence":"first","affiliation":[{"name":"National Research Center for Hematology Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9437-9151","authenticated-orcid":false,"given":"Jianxiang","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Hematology and Blood Disease Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9417-2353","authenticated-orcid":false,"given":"Vikram","family":"Mathews","sequence":"additional","affiliation":[{"name":"Department of Haematology Christian Medical College Vellore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guray","family":"Saydam","sequence":"additional","affiliation":[{"name":"Department of Hematology Ege University Hospital Bornova Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chul Won","family":"Jung","sequence":"additional","affiliation":[{"name":"Samsung Medical Center Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hani Hassan","family":"Al Hashmi","sequence":"additional","affiliation":[{"name":"Adult Hematology &amp; Hematopoietic Stem Cell Transplant Department Oncology Center King Fahad Specialist Hospital Dammam KSA Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Yassin","sequence":"additional","affiliation":[{"name":"National Center for Cancer Care and Research Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1060-8397","authenticated-orcid":false,"given":"Solenn","family":"Le Clanche","sequence":"additional","affiliation":[{"name":"KPL Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darko","family":"Miljkovic","sequence":"additional","affiliation":[{"name":"Novartis Hematology Emerging Growth Markets Novartis Pharma AG Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cassandra","family":"Slader","sequence":"additional","affiliation":[{"name":"Novartis Hematology Emerging Growth Markets Novartis Pharma AG Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0910-3730","authenticated-orcid":false,"given":"Timothy P.","family":"Hughes","sequence":"additional","affiliation":[{"name":"South Australian Health and Medical Research Institute Adelaide SA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,3,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-09-696013"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040258"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199904293401706"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-02-204693"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.66.2866"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200104053441402"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa022457"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-05-501569"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx219"},{"key":"e_1_2_10_11_1","unstructured":"National Comprehensive Cancer Network.NCCN Practice Guidelines in Oncology: Chronic myeloid leukemia. 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