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We analyzed a pooled dataset of three randomized trials including FL patients with advanced disease, conducted by the Swiss Group for Clinical Cancer Research (SAKK). Overall, POD24 was observed in 27% of 318 patients, but rate variance among studies suggested that the rituximab schedule might affect POD24 rate. POD24 was associated with lower 10\u2010year overall survival rates than in the reference group (69% vs. 77%; hazard ratio, 3\u00b712; 95% confidence interval, 1\u00b773\u20135\u00b765). POD24 retains its prognostic validity in patients treated without chemotherapy and may represent a useful end\u2010point for future studies.<\/jats:p>","DOI":"10.1111\/bjh.17045","type":"journal-article","created":{"date-parts":[[2020,8,17]],"date-time":"2020-08-17T19:42:25Z","timestamp":1597693345000},"page":"1031-1034","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Prognostic value of POD24 validation in follicular lymphoma patients initially treated with chemotherapy\u2010free regimens in a pooled analysis of three randomized trials of the Swiss Group for Clinical Cancer Research (SAKK)"],"prefix":"10.1111","volume":"192","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8816-5464","authenticated-orcid":false,"given":"Alden Alberto","family":"Moccia","sequence":"first","affiliation":[{"name":"Clinic of Medical Oncology Oncology Institute of Southern Switzerland Bellinzona 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