{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:31:41Z","timestamp":1790688701919,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T00:00:00Z","timestamp":1600387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100010663","name":"H2020 European Research Council","doi-asserted-by":"publisher","award":["647047, Stand up to Cancer, Flemish Cancer Society, Research Foundation Flanders"],"award-info":[{"award-number":["647047, Stand up to Cancer, Flemish Cancer Society, Research Foundation Flanders"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>This cohort study of the International Network on Cancer, Infertility and Pregnancy (INCIP) reports the maternal and neonatal outcomes of 80 pregnant patients diagnosed with non\u2010Hodgkin lymphoma (NHL) between 1986 and 2019, focussing on 57 (71%) patients with diffuse large B\u2010cell lymphoma (DLBCL). Of all 80 patients, 54 (68%) pregnant patients received chemotherapy; mostly (89%) CHOP\u2010like (cyclophosphamide, doxorubicin, vincristine, and prednisone) regimens. Four early pregnancies were terminated. Among 76 ongoing pregnancies, there was one stillbirth (1\u00b73%). Overall, there was a high incidence of small for gestational age neonates (39%), preterm delivery (52%), obstetric (41%) and neonatal complications (12\u00b75%), and this could not exclusively be explained by the receipt of antenatal chemotherapy. Half of preterm deliveries (46%) were planned in order to tailor oncological treatment. The 3\u2010year progression\u2010free and overall survival for patients with DLBCL treated with rituximab\u2010CHOP was 83\u00b74% and 95\u00b77% for limited stage (<jats:italic>n<\/jats:italic>\u00a0=\u00a029) and 60\u00b76% and 73\u00b73% for advanced stage (<jats:italic>n<\/jats:italic>\u00a0=\u00a015). Of 36 pregnant patients who received rituximab, five (13%) cases with neonatal complications and three (8%) with maternal infections were reported. In conclusion, standard treatment for DLBCL can be offered to pregnant patients in obstetric centres that cater for high\u2010risk patients.<\/jats:p>","DOI":"10.1111\/bjh.17103","type":"journal-article","created":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T13:16:03Z","timestamp":1600434963000},"page":"52-62","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Maternal and neonatal outcomes in 80 patients diagnosed with non\u2010Hodgkin lymphoma during pregnancy: results from the International Network of Cancer, Infertility and Pregnancy"],"prefix":"10.1111","volume":"193","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7485-0839","authenticated-orcid":false,"given":"Charlotte","family":"Maggen","sequence":"first","affiliation":[{"name":"Department of Oncology KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8917-022X","authenticated-orcid":false,"given":"Daan","family":"Dierickx","sequence":"additional","affiliation":[{"name":"Department of Oncology KU Leuven Leuven Belgium"},{"name":"Department of Haematology University Hospitals Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elyce","family":"Cardonick","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Cooper University Health Care Camden NJ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina","family":"Mhallem Gziri","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Cliniques Universitaires St Luc UCL Sint\u2010Lambrechts\u2010Woluwe Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvaro","family":"Cabrera\u2010Garcia","sequence":"additional","affiliation":[{"name":"Hospital Regional de Alta Especialidad de Ixtapaluca (HRAEI) \u201cReference clinic for haemato\u2010oncological diseases during pregnancy CREHER\u201d, Estado de M\u00e9xico M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roman G.","family":"Shmakov","sequence":"additional","affiliation":[{"name":"National Medical Research Centre for Obstetrics Gynaecology and Perinatology named after Academician V.I. Kulakov of the Ministry of Healthcare of Russian Federation Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irit","family":"Avivi","sequence":"additional","affiliation":[{"name":"Tel Aviv Sourasky Medical Centre Tel Aviv Israel"},{"name":"Sackler Faculty of Medicine TA University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Masturzo","sequence":"additional","affiliation":[{"name":"Department Surgical Sciences University of Torino Torino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes J.","family":"Duvekot","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Erasmus MC Cancer Institute Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petronella B.","family":"Ottevanger","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Radboud University Nijmegen Medical Centre Nijmegen Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andie","family":"O\u2019Laughlin","sequence":"additional","affiliation":[{"name":"Cooper Medical School Rowan University Camden NJ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgeniya","family":"Polushkina","sequence":"additional","affiliation":[{"name":"National Medical Research Centre for Obstetrics Gynaecology and Perinatology named after Academician V.I. 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