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The percentage of NHL\u2010related deaths is highest among people aged 75\u201384 years, with a median age at death of 76 years from cases between 2014 and 2018. In light of these recent data, attending physicians of patients with NHL will recognize that the majority of their patients will be of advanced age, with many suffering from a spectrum of frailties. The excess rate of death among older adults with NHL may be related to a range of different factors such as more challenging biologic features, undertreatment received due to a patient\u2019s chronology and treatment\u2010related toxicity. The aim of this review is to provide an updated overview of the knowledge generated over recent years regarding epidemiology, prognosis and treatment options in older adults with lymphoma, focusing on Diffuse Large B\u2010cell Lymphoma (DLBCL) where the most robust evidence base is available.<\/jats:p>","DOI":"10.1111\/bjh.17384","type":"journal-article","created":{"date-parts":[[2021,3,13]],"date-time":"2021-03-13T18:01:20Z","timestamp":1615658480000},"page":"677-685","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The use of frailty assessments in treating older adults with aggressive lymphomas"],"prefix":"10.1111","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7654-8836","authenticated-orcid":false,"given":"Raul","family":"Cordoba","sequence":"first","affiliation":[{"name":"Lymphoma Unit Department of Hematology Fundacion Jimenez Diaz University Hospital Health Research Institute IIS\u2010FJD  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8446-2285","authenticated-orcid":false,"given":"Stefano","family":"Luminari","sequence":"additional","affiliation":[{"name":"Hematology Azienda USL IRCCS of Reggio Emilia  Reggio Emilia Italy"},{"name":"Chimomo Department University of Modena and Reggio Emilia  Reggio Emilia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6631-9749","authenticated-orcid":false,"given":"Toby A.","family":"Eyre","sequence":"additional","affiliation":[{"name":"Oxford Cancer and Haematology Centre Churchill Hospital  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,13]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21590"},{"key":"e_1_2_14_3_1","unstructured":"National Cancer Institute.Surveillance Epidemiology and End Results (SEER) program;2020.https:\/\/seer.cancer.gov\/statfacts\/html\/nhl.html. 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