{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T20:09:13Z","timestamp":1789502953114,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Primary central nervous system (CNS) post\u2010transplant lymphoproliferative disorder (PTLD) in childhood is rare. Twenty\u2010five patients were retrieved from nine European Intergroup for Childhood Non\u2010Hodgkin\u2019s Lymphoma and\/or international Berlin\u2013Frankfurt\u2013M\u00fcnster Study Group members. Types of allografts included kidney (<jats:italic>n<\/jats:italic>\u00a0=\u00a011), liver (<jats:italic>n<\/jats:italic>\u00a0=\u00a04), heart (<jats:italic>n<\/jats:italic>\u00a0=\u00a05), bowel (<jats:italic>n<\/jats:italic>\u00a0=\u00a01) and haematopoietic stem cells (<jats:italic>n<\/jats:italic>\u00a0=\u00a04). Eighteen were male, 16\u00a0\u2265\u00a010\u00a0years old, 21 had monomorphic disease and 24 solid intracranial tumour masses. Four\u2010year event\u2010free and overall survival rates were 50%\u00a0\u00b1\u00a010% and 74%\u00a0\u00b1\u00a09% respectively. This report represents the largest paediatric series of CNS PTLD reported to date, showing favourable survival odds following systemic and intrathecal chemotherapy and rituximab administration.<\/jats:p>","DOI":"10.1111\/bjh.17398","type":"journal-article","created":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T15:08:59Z","timestamp":1616684939000},"page":"1178-1184","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Primary post\u2010transplant lymphoproliferative disorder of the central nervous system: characteristics, management and outcome in 25 paediatric patients"],"prefix":"10.1111","volume":"193","author":[{"given":"Mary M.","family":"Taj","sequence":"first","affiliation":[{"name":"Department of Pediatric Hematology and Oncology Royal Marsden Hospital NHS Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Britta","family":"Maecker\u2010Kolhoff","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology and Oncology Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Ling","sequence":"additional","affiliation":[{"name":"MRC Weatherall Institute of Molecular Medicine University of Oxford John Radcliffe Hospital Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Bomken","sequence":"additional","affiliation":[{"name":"Wolfson Childhood Cancer Research Center Translational and Clinical Research Institute Newcastle University Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1151-829X","authenticated-orcid":false,"given":"Birgit","family":"Burkhardt","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology and Oncology University of M\u00fcnster M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1089-5325","authenticated-orcid":false,"given":"Alan K. 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