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The latter displayed longer survival (median 78 months), compared to MS with synchronous intramedullary AML (<jats:italic>n<\/jats:italic>\u00a0=\u00a032; median 16 months) and <jats:italic>de novo<\/jats:italic> AML without MS (<jats:italic>n<\/jats:italic>\u00a0=\u00a0729; median 22 months; <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b713). However, the difference in survival was no longer apparent after accounting for bone marrow cytogenetic risk status (<jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b767). Treatment\u2010induced MS tumour resolution was not affected by the presence of intramedullary disease (<jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b761). The current study clarifies the prognosis of <jats:italic>de novo<\/jats:italic> isolated MS, in the context of AML.<\/jats:p>","DOI":"10.1111\/bjh.17742","type":"journal-article","created":{"date-parts":[[2021,8,4]],"date-time":"2021-08-04T03:19:40Z","timestamp":1628047180000},"page":"413-416","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["<i>De novo<\/i> isolated myeloid sarcoma: comparative analysis of survival in 19 consecutive cases"],"prefix":"10.1111","volume":"195","author":[{"given":"Kebede H.","family":"Begna","sequence":"first","affiliation":[{"name":"Division of Hematology Department of Internal Medicine Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaya","family":"Kittur","sequence":"additional","affiliation":[{"name":"Division of Hematology Department of Internal Medicine Mayo Clinic Rochester Minnesota 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