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Most CNS lymphomas are of the diffuse large B\u2010cell lymphoma (DLBCL) subtype for which treatment strategies, particularly the use of high\u2010dose methotrexate\u2010based protocols and consolidation with autologous stem cell transplantation, are well established. Other histopathological subtypes of CNS lymphoma are comparatively less common with published data on these rare lymphomas dominated by smaller case series and retrospective reports. Consequently, there exists little clinical consensus on the optimal methods to diagnose and manage these clinically and biologically heterogeneous CNS lymphomas. In this review article, we focus on rarer CNS lymphomas, summarising the available clinical data on incidence, context, diagnostic features, reported management strategies, and clinical outcomes.<\/jats:p>","DOI":"10.1111\/bjh.18128","type":"journal-article","created":{"date-parts":[[2022,3,16]],"date-time":"2022-03-16T07:58:19Z","timestamp":1647417499000},"page":"662-678","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Rare central nervous system lymphomas"],"prefix":"10.1111","volume":"197","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1649-563X","authenticated-orcid":false,"given":"Furqaan Ahmed","family":"Kaji","sequence":"first","affiliation":[{"name":"Clinical Haematology Nottingham University Hospitals NHS Trust Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicol\u00e1s","family":"Martinez\u2010Calle","sequence":"additional","affiliation":[{"name":"Clinical Haematology 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