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In this study, data from six US\u2010based cohorts (568\u2009717 individuals) were used to examine body size and risk of NHL. Over more than 20\u00a0years of follow\u2010up, 11\u2009263 NHLs were identified. Hazard ratios (HRs) and 95% confidence intervals (CI) estimated associations with NHLs for adult body mass index (BMI), height, weight change, waist circumference and predicted fat mass. Adult height was broadly associated with NHL, but most strongly with B\u2010cell NHLs among non\u2010White participants (e.g. HR\n                    <jats:sub>BLACK<\/jats:sub>\n                    \u00a0=\u00a02.06, 95% CI: 1.62\u20132.62). However, the strongest association among the anthropometric traits examined was for young adult BMI and risk of diffuse large B\u2010cell lymphoma (DLBCL), particularly those who maintained a higher BMI into later adulthood. Individuals with BMI over 30\u00a0kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    throughout adulthood had more than double the DLBCL risk (HR\u00a0=\u00a02.67, 95% CI: 1.71\u20134.17) compared to BMI 18.5\u201322.9\u00a0kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    . Other anthropometric traits were not associated with NHL after controlling for BMI. These results suggest that sustained high BMI is a major driver of DLBCL risk. If confirmed, we estimate that up to 23.5% of all DLBCLs (and 11.1% of all NHLs) may be prevented with avoidance of young adult obesity.\n                  <\/jats:p>","DOI":"10.1111\/bjh.18150","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T05:20:44Z","timestamp":1648531244000},"page":"714-727","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Body size and risk of\n                    <scp>non\u2010Hodgkin<\/scp>\n                    lymphoma by subtype: A pooled analysis from six prospective cohorts in the United States"],"prefix":"10.1111","volume":"197","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2419-8536","authenticated-orcid":false,"given":"Lauren R.","family":"Teras","sequence":"first","affiliation":[{"name":"Department of Population Science American Cancer Society  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly A.","family":"Bertrand","sequence":"additional","affiliation":[{"name":"Slone Epidemiology Center Boston University  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily L.","family":"Deubler","sequence":"additional","affiliation":[{"name":"Department of Population Science American Cancer Society  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun R.","family":"Chao","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California  Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"James V.","family":"Lacey","sequence":"additional","affiliation":[{"name":"Beckman Research Institute, City of Hope  Duarte California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alpa V.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Population Science American Cancer Society  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard A.","family":"Rosner","sequence":"additional","affiliation":[{"name":"Channing Division of Network Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Biostatistics Harvard TH Chan School of Public Health  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Hsiang","family":"Shu","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation Kaiser Permanente Southern California  Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Wang","sequence":"additional","affiliation":[{"name":"Channing Division of Network Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlie","family":"Zhong","sequence":"additional","affiliation":[{"name":"Beckman Research Institute, City of Hope  Duarte California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2597-9393","authenticated-orcid":false,"given":"Sophia S.","family":"Wang","sequence":"additional","affiliation":[{"name":"Beckman Research Institute, City of Hope  Duarte California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda M.","family":"Birmann","sequence":"additional","affiliation":[{"name":"Channing Division of Network Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"e_1_2_8_3_1","volume-title":"SEER cancer statistics review, 1975\u20132017","author":"Howlader NNA","year":"2020"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","unstructured":"TerasLR DeSantisCE CerhanJR MortonLM JemalA FlowersCRJCacjfc.2016 US lymphoid malignancy statistics by World Health Organization subtypes.2016;66:443\u201359.","DOI":"10.3322\/caac.21357"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/oso\/9780190238667.003.0040"},{"key":"e_1_2_8_6_1","doi-asserted-by":"crossref","unstructured":"WangY BeydounMA MinJ XueH KaminskyLA CheskinLJ.Has the prevalence of overweight obesity and central obesity levelled off in the United States? 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