{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T21:50:27Z","timestamp":1769550627324,"version":"3.49.0"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T00:00:00Z","timestamp":1649635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>Dosing and monitoring of argatroban for treatment of heparin\u2010induced thrombocytopenia (HIT) remain uncertain. Marchetti and colleagues critically and systematically reviewed their institutional experience using this direct thrombin inhibitor to treat patients with laboratory\u2010confirmed HIT, and have formulated several practical recommendations for managing this challenging clinical situation.<\/jats:p><jats:p>Commentary on: Marchetti <jats:italic>et al<\/jats:italic>. Managing argatroban in heparin\u2010induced thrombocytopenia: A retrospective analysis of 729 treatment days in 32 patients with confirmed heparin\u2010induced thrombocytopenia. <jats:italic>Br J Haematol<\/jats:italic>. 2022;197:766\u2010790<\/jats:p>","DOI":"10.1111\/bjh.18153","type":"journal-article","created":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T16:09:22Z","timestamp":1649693362000},"page":"653-655","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["How to dose and monitor argatroban for treatment of <scp>HIT<\/scp>"],"prefix":"10.1111","volume":"197","author":[{"given":"Theodore E.","family":"Warkentin","sequence":"first","affiliation":[{"name":"Department of Pathology and Molecular Medicine (Division of Transfusion Medicine) and Department of Medicine (Division of Hematology and Thromboembolism) McMaster University  Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,4,11]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(96)00258-6"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.20.2518"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2018024489"},{"key":"e_1_2_3_5_1","first-page":"356","volume-title":"Heparin\u2010Induced Thrombocytopenia","author":"Rice L","year":"2013"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12993"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-015-1109-0"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.14.1838"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.15.1849"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2011.1.143"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1291375"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2013.823946"},{"key":"e_1_2_3_13_1","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1111\/bjh.18120","article-title":"Managing argatroban in heparin\u2010induced thrombocytopenia: a retrospective analysis of 729 treatment days in 32 patients with confirmed HIT","volume":"197","author":"Marchetti M","year":"2022","journal-title":"Br J Haematol"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH15-11-0847"},{"key":"e_1_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.15.1849"}],"container-title":["British Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.18153","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bjh.18153","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.18153","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T03:10:06Z","timestamp":1692846606000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bjh.18153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,11]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1111\/bjh.18153"],"URL":"https:\/\/doi.org\/10.1111\/bjh.18153","archive":["Portico"],"relation":{},"ISSN":["0007-1048","1365-2141"],"issn-type":[{"value":"0007-1048","type":"print"},{"value":"1365-2141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,11]]},"assertion":[{"value":"2022-03-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}