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Qi <jats:italic>et al.<\/jats:italic> show that hypoxia\u2010inducible factor\u20101\u03b1 (HIF\u20101\u03b1) may be a previously unrecognized driver of this endothelial injury syndrome.<\/jats:p><jats:p>Commentary on Qi <jats:italic>et al<\/jats:italic>. Upregulation of HIF\u20101\u03b1 contributes to complement activation in transplantation\u2010associated thrombotic microangiopathy. <jats:italic>Br J Haematol<\/jats:italic>. 2022 199:603\u2013615.<\/jats:p>","DOI":"10.1111\/bjh.18402","type":"journal-article","created":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T07:34:27Z","timestamp":1660030467000},"page":"477-479","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["What complements complement in transplant\u2010associated thrombotic microangiopathy?"],"prefix":"10.1111","volume":"199","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3652-0003","authenticated-orcid":false,"given":"Anthony","family":"Sabulski","sequence":"first","affiliation":[{"name":"Division of Bone Marrow Transplantation and Immune Deficiency Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati  Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonata","family":"Jodele","sequence":"additional","affiliation":[{"name":"Division of Bone Marrow Transplantation and Immune Deficiency Cincinnati Children's Hospital Medical Center  Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati  Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,9]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood\u20102014\u201003\u2010564997"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019004218"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtct.2022.04.019"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2020003988"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/17474086.2021.1960816"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2019.00133"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2020001515"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood\u20102017\u201005\u2010782870"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.18377"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2008.12"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood\u20102015\u201008\u2010663435"}],"container-title":["British Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.18402","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bjh.18402","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.18402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T05:34:25Z","timestamp":1692682465000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bjh.18402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,9]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1111\/bjh.18402"],"URL":"https:\/\/doi.org\/10.1111\/bjh.18402","archive":["Portico"],"relation":{},"ISSN":["0007-1048","1365-2141"],"issn-type":[{"value":"0007-1048","type":"print"},{"value":"1365-2141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,9]]},"assertion":[{"value":"2022-07-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}