{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T19:50:00Z","timestamp":1788292200511,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T00:00:00Z","timestamp":1668729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    We conducted a Surveillance, Epidemiology, and End Results Program (SEER\u201018) registry analysis of classical Hodgkin lymphoma (cHL) patients more than 60\u2009years old and compared outcomes of those diagnosed between 2006 and 2010 (cohort 1) to those identified between 2011 and 2015 (cohort 2) based on treatment era and race. Cohort 1 had a median overall survival (OS) of 4\u2009years and cohort 2 had a median OS of 4.75\u2009years [hazard ratio (HR): 0.92 (0.85\u20131.00);\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u20090.052]. Non\u2010Hispanic blacks (NHBs) had a similar 5\u2010year OS compared to non\u2010Hispanic whites (NHWs) of 48.6% vs. 50.2% (HR: 0.95 [0.79\u20131.15];\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&gt;\u20090.99); on the contrary, Hispanics had worse 5\u2010year OS of 41.8% vs. 48.6% (HR: 1.24 [1.09\u20131.41];\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u20090.001). NHW was the only race that had improvement in 5\u2010year OS in 2011\u20132015 compared to 2006\u20132010 (51% vs. 46.5%,\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u20090.002). In the multivariable analysis, older age, male gender, stage III\u2013IV, unmarried status, Hispanic race, lack of chemotherapy, and diagnosis in 2006\u20132010 were associated with worse OS. Lymphoma was the most common cause of death in 60% of patients. In conclusion, elderly cHL patients diagnosed after 2010 had improved OS by nine months that was most prevalent in NHWs, and disparity in OS existed between NHWs and Hispanics throughout the study period.\n                  <\/jats:p>","DOI":"10.1111\/bjh.18564","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T21:45:32Z","timestamp":1668807932000},"page":"579-586","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A comprehensive SEER registry analysis of elderly patients with classical Hodgkin lymphoma based on treatment era and race"],"prefix":"10.1111","volume":"200","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6054-5238","authenticated-orcid":false,"given":"Harsh","family":"Shah","sequence":"first","affiliation":[{"name":"University of Utah\/Huntsman Cancer Center  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyejeong","family":"Jang","sequence":"additional","affiliation":[{"name":"Biostatistics and Bioinformatics Core Karmanos Cancer Institute  Detroit Michigan USA"},{"name":"Department of Oncology, School of Medicine Wayne State University  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seongho","family":"Kim","sequence":"additional","affiliation":[{"name":"Biostatistics and Bioinformatics Core Karmanos Cancer Institute  Detroit Michigan USA"},{"name":"Department of Oncology, School of Medicine Wayne State University  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad S.","family":"Halwani","sequence":"additional","affiliation":[{"name":"Huntsman Cancer Institute  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0000000000000464"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hon.2590"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.11.080"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3759"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-15-0756"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr578"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2014.983097"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2016.05.004"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-08-595801"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1510093"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.02.7243"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.16525"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2020-136356"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0b013e328348c6c1"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.00264"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1408648"},{"issue":"6","key":"e_1_2_10_18_1","first-page":"3035","article-title":"Effect of radiation therapy on survival in Hodgkin's lymphoma: a SEER data analysis","volume":"37","author":"Master S","year":"2017","journal-title":"Anticancer Res"}],"container-title":["British Journal of 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