{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T22:38:18Z","timestamp":1765233498804,"version":"3.40.5"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T00:00:00Z","timestamp":1676419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Immune thrombocytopenia (ITP) was reported as a rare complication of COVID\u201019 vaccines. We conducted a retrospective single\u2010center analysis of all ITP cases detected in 2021 and compared the quantity with the pre\u2010vaccination years, from 2018 to 2020. In 2021, a two\u2010fold increase in ITP cases was identified compared to previous years; 11 of 40 cases (27.5%) were considered COVID\u201019\u2010vaccine related. Our study highlights an increase in ITP cases at our institution, probably related to COVID\u201019 vaccinations. Further studies are needed to investigate this finding globally.<\/jats:p>","DOI":"10.1111\/bjh.18686","type":"journal-article","created":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T05:54:00Z","timestamp":1676526840000},"page":"222-226","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Increased incidence of immune thrombocytopenia (<scp>ITP<\/scp>) in 2021 correlating with the ongoing vaccination campaign against <scp>COVID<\/scp>\u201019 in a tertiary center \u2013 A monocentric analysis"],"prefix":"10.1111","volume":"201","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6494-5105","authenticated-orcid":false,"given":"C.","family":"Schaefers","sequence":"first","affiliation":[{"name":"Department of Oncology, Hematology and Stem Cell Transplantation with Division of Pneumology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5603-1469","authenticated-orcid":false,"given":"F.\u2010O.","family":"Paulsen","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hematology and Stem Cell Transplantation with Division of Pneumology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Frenzel","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hematology and Stem Cell Transplantation with Division of Pneumology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Weisel","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hematology and Stem Cell Transplantation with Division of Pneumology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Bokemeyer","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hematology and Stem Cell Transplantation with Division of Pneumology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6023-6336","authenticated-orcid":false,"given":"C.","family":"Seidel","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hematology and Stem Cell Transplantation with Division of Pneumology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,15]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-021-01408-4"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00677-2"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n1088"},{"key":"e_1_2_12_5_1","unstructured":"EMA.COVID\u201019 vaccines safety update 2022. Available from:https:\/\/www.ema.europa.eu\/en\/documents\/covid\u201019\u2010vaccine\u2010safety\u2010update\/covid\u201019\u2010vaccines\u2010safety\u2010update\u201014\u2010july\u20102022_en.pdf."},{"key":"e_1_2_12_6_1","first-page":"996","article-title":"Immune thrombocytopenic purpura after vaccination with COVID\u201019 vaccine (ChAdOx1 nCov\u201019)","volume":"138","author":"Paulsen F\u2010O","year":"2021","journal-title":"Blood"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2021013411"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16368"},{"key":"e_1_2_12_9_1","unstructured":"MatzdorffA HolzhauerS K\u00fchneT MeyerO OstermannH Pabinger\u2010FaschingI RummelMJ SachsU W\u00f6rmannB.Leitlinie Immunthrombozytopenie (ITP).2021."},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-07-162503"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.32614\/RJ-2021-053"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2021006379"}],"container-title":["British Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.18686","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bjh.18686","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.18686","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T19:16:12Z","timestamp":1692558972000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bjh.18686"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,15]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1111\/bjh.18686"],"URL":"https:\/\/doi.org\/10.1111\/bjh.18686","archive":["Portico"],"relation":{},"ISSN":["0007-1048","1365-2141"],"issn-type":[{"type":"print","value":"0007-1048"},{"type":"electronic","value":"1365-2141"}],"subject":[],"published":{"date-parts":[[2023,2,15]]},"assertion":[{"value":"2022-10-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}